Patents by Inventor Benjamin J. Feldman
Benjamin J. Feldman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240080647Abstract: A system for interoperating and communicating data from a device having a communications gateway and at least one tactical device connected to an electrified rail providing electrical power. The system includes at least one processor, and at least one non-transitory computer-readable data storage device storing data instructions that, when executed by the at least one processor, cause the system to receive an event from the device, determine whether the event triggers a workflow, and execute an action on the device in response to the workflow being triggered.Type: ApplicationFiled: February 28, 2023Publication date: March 7, 2024Applicant: T-Worx Holdings, LLCInventors: Jeffrey R. Musa, Wayne J. Taylor, Gary W. Callsen, Tyler J. Miller, Joseph D. Ellena, Benjamin F. Feldman
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Patent number: 11918355Abstract: Apparatus, methods, and systems for detecting alcohol concentrations of an individual, and in particular in vivo alcohol concentrations of an individual. Alcohol sensing compositions include at least one alcohol-responsive active area comprising a concerted enzyme system having at least a first enzyme and second enzyme capable of acting in concert to facilitate the detection of alcohol. At least one of the enzymes in the concerted enzyme system is a ketoreductase.Type: GrantFiled: August 28, 2020Date of Patent: March 5, 2024Assignee: Abbott Diabetes Care Inc.Inventors: Benjamin J. Feldman, Tianmei Ouyang, Ahmed Hisham Wali
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Publication number: 20240027390Abstract: Analyte sensor comprises a substrate having an upper surface including a first portion and a second exposed portion, an electrode layer disposed on the first portion and having an elongate body comprising a proximal end and a distal end, the electrode layer including an active working electrode area having a surface area of between 0.15 mm2 to 0.25 mm2, at least one sensing spot with at least one analyte responsive enzyme disposed on the active working electrode area. Additional analyte sensors are disclosed.Type: ApplicationFiled: July 18, 2023Publication date: January 25, 2024Applicant: ABBOTT DIABETES CARE INC.Inventors: Udo Hoss, Max Garbett, Andrew James Bull, Stephen Oja, Benjamin J. Feldman, Lam N. Tran, Jean-Pierre Babka, Mark Stephen Yahnke, Tahir S. Khan, Adrian Petyt, Mark Alan Schulz, Andrew McGibbon, Owen Daniel Reynolds
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Publication number: 20230337976Abstract: Systems, devices and methods are provided for the monitoring and management of an individual's wellness and nutrition using analyte data from an in vivo analyte sensor. Generally, a sensor control device is provided for wear on the body. The sensor control device can include an in vivo analyte sensor for measuring an analyte level in a bodily fluid, an accelerometer for measuring the physical activity level of the subject, as well as communications circuitry for wirelessly transmitting data to a reader device. Furthermore, disclosed herein are embodiments of various graphical user interfaces for displaying analyte metrics on a reader device, comparing the analyte response of various foods and/or meals, modifying daily nutrient recommendations based on analyte metrics and physical activity level measurements, and other features described herein. Additionally, the embodiments disclosed herein can be used to monitor various types of analytes.Type: ApplicationFiled: June 22, 2023Publication date: October 26, 2023Inventors: Jean-Pierre COLE, Benjamin J. FELDMAN, Udo HOSS, Namvar KIAIE, Frederic T. ARBOGAST
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Publication number: 20230248271Abstract: Analyte sensors are being increasingly employed for monitoring various analytes in vivo. Analyte sensors configured to monitor multiple analytes are also in development. Sufficient sensitivity for low-abundance analytes and multiple analytes having differing membrane permeability values may complicate analyte detection in some cases. Analyte sensors may feature enhancements to address one or both of these issues. Some analyte sensors may comprise a carbon working electrode comprising a dielectric substrate, one or more apertures extending through the dielectric substrate and filled with a carbon conductor pillar, a carbon conductor coating on a first face of the dielectric substrate in direct contact with each carbon conductor pillar, and one or more active areas on a second face of the dielectric substrate in electrical communication with the carbon conductor pillars.Type: ApplicationFiled: May 13, 2021Publication date: August 10, 2023Inventors: Zenghe LIU, Cade B. FOX, Jonathan D. MCCANLESS, Benjamin J. FELDMAN
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Publication number: 20230157596Abstract: The present disclosure provides an analyte sensor for use in detecting glutamate. In certain embodiments, a glutamate-responsive active site of a presently disclosed analyte sensor includes a glutamate oxidase and a redox mediator disposed upon a surface of a working electrode. The present disclosure further provides methods for detecting glutamate using the disclosed analyte sensors.Type: ApplicationFiled: November 14, 2022Publication date: May 25, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Rifat Emrah OZEL, Stephen OJA, Benjamin J. FELDMAN
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Publication number: 20230128038Abstract: Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.Type: ApplicationFiled: December 19, 2022Publication date: April 27, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. FELDMAN, Mark K. SLOAN, Ashwin KUMAR, Namvar KIAIE, Michael R. LOVE
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Publication number: 20230121367Abstract: Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.Type: ApplicationFiled: December 19, 2022Publication date: April 20, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. FELDMAN, Mark K. SLOAN, Ashwin KUMAR, Namvar KIAIE, Michael R. LOVE
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Publication number: 20230119512Abstract: Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.Type: ApplicationFiled: December 20, 2022Publication date: April 20, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. FELDMAN, Mark K. SLOAN, Ashwin KUMAR, Namvar KIAIE, Michael R. LOVE
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Publication number: 20230121101Abstract: Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.Type: ApplicationFiled: December 20, 2022Publication date: April 20, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. FELDMAN, Mark K. SLOAN, Ashwin KUMAR, Namvar KIAIE, Michael R. LOVE
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Publication number: 20230122702Abstract: Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.Type: ApplicationFiled: December 20, 2022Publication date: April 20, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. FELDMAN, Mark K. SLOAN, Ashwin KUMAR, Namvar KIAIE, Michael R. LOVE
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Publication number: 20230118818Abstract: Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.Type: ApplicationFiled: December 20, 2022Publication date: April 20, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. FELDMAN, Mark K. SLOAN, Ashwin KUMAR, Namvar KIAIE, Michael R. LOVE
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Publication number: 20230123384Abstract: Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.Type: ApplicationFiled: December 20, 2022Publication date: April 20, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. FELDMAN, Mark K. SLOAN, Ashwin KUMAR, Namvar KIAIE, Michael R. LOVE
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Publication number: 20230121769Abstract: Glucose and ketones may be dysregulated singularly or concurrently in certain physiological conditions and may be advantageously assayed together using an analyte sensor capable of detecting both analytes. Certain analyte sensors capable of dual detection may comprise a first working electrode and a second working electrode, a ketones-responsive active area disposed upon a surface of the first working electrode, a glucose-responsive active area comprising a glucose-responsive enzyme disposed upon a surface of the second working electrode, a membrane having a first portion overcoating the ketones-responsive active area and a second portion overcoating the glucose-responsive active area, in which the first portion and the second portion have different compositions. The ketones-responsive active area comprises an enzyme system comprising at least two enzymes that are capable of acting in concert to facilitate detection of ketones.Type: ApplicationFiled: December 19, 2022Publication date: April 20, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Benjamin J. FELDMAN, Mark K. SLOAN, Ashwin KUMAR, Namvar KIAIE, Michael R. LOVE
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Publication number: 20230079165Abstract: Systems, devices and methods are provided for the monitoring and management of an individual's wellness and nutrition using analyte data from an in vivo analyte sensor. Generally, a sensor control device is provided for wear on the body. The sensor control device can include an in vivo analyte sensor for measuring an analyte level in a bodily fluid, an accelerometer for measuring the physical activity level of the subject, as well as communications circuitry for wirelessly transmitting data to a reader device. Furthermore, disclosed herein are embodiments of various graphical user interfaces for displaying analyte metrics on a reader device, comparing the analyte response of various foods and/or meals, modifying daily nutrient recommendations based on analyte metrics and physical activity level measurements, and other features described herein. Additionally, the embodiments disclosed herein can be used to monitor various types of analytes.Type: ApplicationFiled: November 10, 2022Publication date: March 16, 2023Inventors: Jean-Pierre COLE, Benjamin J. FELDMAN, Udo HOSS, Namvar KIAIE, Frederic T. Arbogast
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Publication number: 20230080107Abstract: NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P)+) or derivative thereof; an NAD(P)+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.Type: ApplicationFiled: August 11, 2022Publication date: March 16, 2023Applicant: Abbott Diabetes Care Inc.Inventors: Tianmei OUYANG, Benjamin J. FELDMAN
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Publication number: 20230054564Abstract: NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P)+) or derivative thereof; an NAD(P)+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.Type: ApplicationFiled: August 11, 2022Publication date: February 23, 2023Applicant: ABBOTT DIABETES CARE INC.Inventors: Tianmei OUYANG, Benjamin J. FELDMAN
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Publication number: 20220395202Abstract: NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P)+) or derivative thereof; an NAD(P)+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.Type: ApplicationFiled: August 8, 2022Publication date: December 15, 2022Applicant: ABBOTT DIABETES CARE INC.Inventors: Tianmei OUYANG, Benjamin J. FELDMAN
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Publication number: 20220396820Abstract: NADP-dependent oxidoreductase compositions, and electrodes, sensors and systems that include the same. Analyte sensors include an electrode having a sensing layer disposed thereon, the sensing layer comprising a polymer and an enzyme composition distributed therein. The enzyme composition includes nicotinamide adenine dinucleotide phosphate (NAD(P)+) or derivative thereof; an NAD(P)+-dependent dehydrogenase; an NAD(P)H oxidoreductase; and an electron transfer agent comprising a transition metal complex.Type: ApplicationFiled: August 10, 2022Publication date: December 15, 2022Applicant: ABBOTT DIABETES CARE INC.Inventors: Tianmei OUYANG, Benjamin J. FELDMAN
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Publication number: 20220386906Abstract: An analyte sensor including an antiglycolytic agent or a precursor thereof and a chelating agent that stabilizes the antiglycolytic agent positioned proximate to the working electrode of the sensor. Also provided are systems and methods of using the electrochemical analyte sensors in analyte monitoring.Type: ApplicationFiled: August 5, 2022Publication date: December 8, 2022Applicant: Abbott Diabetes Care, Inc.Inventors: Tianmei OUYANG, Zenghe LIU, Hyun CHO, Benjamin J. FELDMAN