Abstract: A method of operating an aircraft including a gas turbine engine and a fuel tank arranged to provide fuel to the gas turbine engine. The method includes: determining at least one fuel characteristic of the fuel arranged to be provided to the gas turbine engine; and proposing or initiating a change to a flight profile of the aircraft based on the at least one fuel characteristic. For example, intended route and/or altitude of the aircraft may be changed based on the one or more fuel characteristics.

Abstract: This document relates to methods and materials involved in identifying and/or treating mammals having membranous nephropathy (e.g., membranous nephropathy with an elevated level of a Semaphorin 3B polypeptide in the glomerular basement membrane (GBM)). For example, methods and materials for administering one or more immunosuppressive agents (e.g., corticosteroids, cyclosporine, or a B-cell reduction or depletion agent such as Rituximab) to treat a mammal (e.g., a human) having membranous nephropathy are provided.

Abstract: This document relates to methods and materials involved in identifying and/or treating mammals having membranous nephropathy (e.g., membranous nephropathy with an elevated level of a PCDH7 polypeptide in the glomerular basement membrane (GBM)). For example, methods and materials for administering one or more immunosuppressive agents (e.g., corticosteroids, cyclosporine, or a B-cell reduction or depletion agent such as Rituximab) to treat a mammal (e.g., a human) having membranous nephropathy are provided.

Abstract: This document relates to methods and materials involved in identifying and/or treating mammals having membranous nephropathy (e.g., membranous nephropathy with an elevated level of a neural epidermal growth factor (EGF)-like 1 (NELL-1) polypeptide in the glomerular basement membrane (GBM)). For example, methods and materials for administering one or more immunosuppressive agents (e.g., corticosteroids, cyclosporine, or a B-cell reduction or depletion agent such as Rituximab) to treat a mammal (e.g., a human) having membranous nephropathy are provided.

Abstract: A perimeter light blockout system for minimizing light leakage between light gaps such as, for example, between the sides of a covering (e.g., shade) of an architectural-structure covering and the interior side surfaces of a window frame, or between the covering and the outer surface of an interior wall is disclosed. The perimeter light blockout system including a light blocking device and a mounting element for coupling the light blocking device to the interior side surface of the window frame, or the outer surface of the interior wall. The light blocking device may include rear and front channel members. The mounting element may be a mounting extrusion. Alternatively, the mounting element may be a spring clip. In use, the light blocking device may be adapted and configured so as not to contact the covering as the covering moves between extended and retracted positions. The mounting element may include a degree of adjustment so that the light blocking device may be aligned with an out-of-skew window frame.

Abstract: This document provides methods and materials involved in identifying and treating mammals (e.g., humans) having membranous nephropathy. For example, methods and materials for detecting the presence of autoantibodies specific for an EXT1 and/or EXT2 polypeptide as well as methods and materials for detecting the presence of kidney tissue having an elevated level of an EXT1 and/or EXT2 polypeptide are provided. In addition, methods and materials for treating membranous nephropathy by administering an immunosuppressant are provided.

Abstract: A perimeter light blockout system for minimizing light leakage between light gaps such as, for example, between the sides of a covering (e.g., shade) of an architectural-structure covering and the interior side surfaces of a window frame, or between the covering and the outer surface of an interior wall is disclosed. The perimeter light blockout system including a light blocking device and a mounting element for coupling the light blocking device to the interior side surface of the window frame, or the outer surface of the interior wall. The light blocking device may include rear and front channel members. The mounting element may be a mounting extrusion. Alternatively, the mounting element may be a spring clip. In use, the light blocking device may be adapted and configured so as not to contact the covering as the covering moves between extended and retracted positions. The mounting element may include a degree of adjustment so that the light blocking device may be aligned with an out-of-skew window frame.

Abstract: A perimeter light blockout system for minimizing light leakage between light gaps such as, for example, between the sides of a covering (e.g., shade) of an architectural-structure covering and the interior side surfaces of a window frame, or between the covering and the outer surface of an interior wall is disclosed. The perimeter light blockout system including a light blocking device and a mounting element for coupling the light blocking device to the interior side surface of the window frame, or the outer surface of the interior wall. The light blocking device may include rear and front channel members. The mounting element may be a mounting extrusion. Alternatively, the mounting element may be a spring clip. In use, the light blocking device may be adapted and configured so as not to contact the covering as the covering moves between extended and retracted positions. The mounting element may include a degree of adjustment so that the light blocking device may be aligned with an out-of-skew window frame.

Abstract: A perimeter light blockout system for minimizing light leakage between light gaps such as, for example, between the sides of a covering (e.g., shade) of an architectural-structure covering and the interior side surfaces of a window frame, or between the covering and the outer surface of an interior wall is disclosed. The perimeter light blockout system including a light blocking device and a mounting element for coupling the light blocking device to the interior side surface of the window frame, or the outer surface of the interior wall. The light blocking device may include rear and front channel members. The mounting element may be a mounting extrusion. Alternatively, the mounting element may be a spring clip. In use, the light blocking device may be adapted and configured so as not to contact the covering as the covering moves between extended and retracted positions. The mounting element may include a degree of adjustment so that the light blocking device may be aligned with an out-of-skew window frame.