Patents by Inventor Benjamin J. Moga
Benjamin J. Moga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8986250Abstract: A drug delivery platform is provided for delivering a controlled infusion of a drug to an individual. The drug delivery platform includes a reservoir for receiving the drug therein and a pressure source engageable with the reservoir. The pressure source is movable between a first configuration and a second configuration wherein the pressure source exerts a pressure on the reservoir to urge the drug therefrom. An output conduit is provided for transmitting the drug into the individual. An actuation mechanism is operatively connected to the pressure source and the output conduit. The actuation mechanism is movable between a non-actuated position and an actuated position wherein pressure source moves from the first configuration to the second configuration and wherein the input of the output conduit communicates with the drug and the output end of the output conduit is receivable in the individual.Type: GrantFiled: August 1, 2008Date of Patent: March 24, 2015Assignees: Wisconsin Alumni Research Foundation, Ration, Inc.Inventors: David J. Beebe, Benjamin J. Moga, Tony Escarcega, Kent Chase
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Patent number: 8888757Abstract: An active microneedle array and method are provided for penetrating an outer layer of an epidermis. The active microneedle array includes a base having first and second sides. The first side of the base is engageable with the epidermis. A microneedle projects from the first side of the base. The microneedle is moveable between a first initial configuration and a second deformed configuration in response to engagement with the epidermis so as to form a passageway therein.Type: GrantFiled: May 27, 2009Date of Patent: November 18, 2014Assignee: Wisconsin Alumni Research FoundationInventors: Benjamin J. Moga, David J. Beebe
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Patent number: 8795259Abstract: A drug delivery platform is provided for delivering a controlled infusion of a drug to an individual. The drug delivery platform includes a reservoir for receiving the drug therein and a hydrogel engageable with the reservoir. The hydrogel is movable between a first configuration and a second configuration wherein the hydrogel exerts a pressure on the reservoir to urge the drug therefrom in response to a predetermined stimulus. A flow guide distributes the predetermined stimulus over the hydrogel in response to activation by an individual.Type: GrantFiled: August 1, 2008Date of Patent: August 5, 2014Assignee: Wisconsin Alumni Research FoundationInventors: David J. Beebe, Benjamin J. Moga, Tony Escarcega, Kent Chase
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Patent number: 8328757Abstract: A bladder arrangement is provided for a microneedle-based drug delivery device. The bladder arrangement includes a flexible membrane having an inner surface, an outer surface and an outer periphery. A bladder member, having a rigidity greater than the flexible membrane, includes an inner surface, an outer surface and an outer periphery. The inner surface of the flexible membrane and the inner surface of the bladder member define a chamber for receiving a drug therein. At least one microneedle is operatively connected to the bladder member. The at least one microneedle has an input and an output receivable within the individual. A valve operatively connects the input of the at least one microneedle and the chamber.Type: GrantFiled: January 8, 2010Date of Patent: December 11, 2012Assignee: Wisconsin Alumni Research FoundationInventors: David J. Beebe, Benjamin J. Moga, Kent B. Chase, Garrick D. S. Smith, Jake W. Myre
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Publication number: 20110172638Abstract: An apparatus for delivering a drug to a subject is provided. The apparatus includes a housing, a microneedle coupled to the housing and configured to extend from the housing when activated, an activation control coupled to the housing and an outer shell. The outer shell includes a top wall having an inner surface and a sidewall extending from the top wall, the sidewall having an inner surface. The outer shell includes a first attachment structure configured to attach to the housing. The outer shell covers the activation control when the first attachment structure is attached to the housing. The outer shell includes a second attachment structure configured to attach to the housing. The outer shell covers the activated microneedle when the second attachment structure is attached to the housing.Type: ApplicationFiled: January 8, 2010Publication date: July 14, 2011Inventors: Benjamin J. Moga, Kent Chase, Garrick D.S. Smith
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Publication number: 20110172609Abstract: A device for delivering a drug to a subject is provided. The device includes a drug reservoir, a conduit coupled to the drug reservoir and a microneedle component. The microneedle component includes a body, an engagement structure coupling the microneedle component to the conduit, a hollow microneedle extending from the body, and a handling feature located on the body. The microneedle component is configured to be releasably coupled to an assembly tool via the handling feature during assembly of the device.Type: ApplicationFiled: January 8, 2010Publication date: July 14, 2011Inventors: Benjamin J. Moga, Kent Chase, Garrick D.S. Smith
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Publication number: 20110172637Abstract: A drug delivery device for delivering a drug to a subject includes a microneedle configured to facilitate delivery of the drug to the subject. The microneedle includes a tip portion and is moveable from an inactive position to an activated position. When the microneedle is moved to the activated position, the tip portion of the microneedle is configured to penetrate the skin of the subject. The drug delivery device includes a tissue support structure that includes a channel and an engagement element. The channel has a first end and a second end and is in axial alignment with the microneedle. At least the tip portion of the microneedle extends past the second end of the channel in the activated position.Type: ApplicationFiled: January 8, 2010Publication date: July 14, 2011Inventors: Benjamin J. Moga, Kent Chase, Garrick D.S. Smith
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Publication number: 20110172639Abstract: A device for delivering a drug into the skin of a subject is provided. The device includes a drug reservoir and a microneedle having a tip, a length, and a tip sharpness. The microneedle is coupled to the reservoir. The device includes a microneedle actuator coupled to the microneedle configured to drive the microneedle into the skin of the subject upon activation. The tip sharpness and the actuator allow the microneedle to pass through an outer layer of the skin upon activation, and the length is limited such that the tip does not extend past a desired depth below the surface of the skin of the subject, wherein the desired depth is located in the papillary dermis or the reticular dermis.Type: ApplicationFiled: January 8, 2010Publication date: July 14, 2011Inventors: Benjamin J. Moga, Kent B. Chase, Garrick D.S. Smith
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Publication number: 20110172645Abstract: A drug delivery device for delivering a drug to a subject is provided. The drug delivery device includes a housing, a drug reservoir supported by the housing containing the drug and a hollow microneedle supported by the housing. The hollow microneedle is moveable from an inactive position to an activated position, wherein, when the hollow microneedle is moved to the activated position, the tip portion of the hollow microneedle is configured to penetrate the skin of the subject. The drug delivery device includes a channel having an input in communication with the drug reservoir and an output in communication with the hollow microneedle. The channel provides fluid communication between the drug reservoir and the hollow microneedle, such that the drug is permitted to flow from the drug reservoir through the channel and through the hollow microneedle.Type: ApplicationFiled: January 8, 2010Publication date: July 14, 2011Inventors: Benjamin J. Moga, Kent B. Chase, Garrick D.S. Smith
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Publication number: 20110172601Abstract: A bladder arrangement is provided for a microneedle-based drug delivery device. The bladder arrangement includes a flexible membrane having an inner surface, an outer surface and an outer periphery. A bladder member, having a rigidity greater than the flexible membrane, includes an inner surface, an outer surface and an outer periphery. The inner surface of the flexible membrane and the inner surface of the bladder member define a chamber for receiving a drug therein. At least one microneedle is operatively connected to the bladder member. The at least one microneedle has an input and an output receivable within the individual. A valve operatively connects the input of the at least one microneedle and the chamber.Type: ApplicationFiled: January 8, 2010Publication date: July 14, 2011Inventors: David J. Beebe, Benjamin J. Moga, Kent B. Chase, Garrick D.S. Smith, Jake W. Myre
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Publication number: 20100305518Abstract: An active microneedle array and method are provided for penetrating an outer layer of the epidermis. The active microneedle array includes a base having first and second sides. The first side of the base is engageable with the epidermis. A microneedle projects from the first side of the base. The microneedle is moveable between a first initial configuration and a second deformed configuration in response to engagement with the epidermis so as to form a passageway therein.Type: ApplicationFiled: May 27, 2009Publication date: December 2, 2010Inventors: Benjamin J. Moga, David J. Beebe
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Publication number: 20100151564Abstract: A biological work station for culturing and monitoring cells includes a laminar flow bench and an incubator disposed on the bench. The bench includes a work surface adjacent the incubator that allows experiments and other manipulations to be performed within the confines of the laminar flow bench. An imaging system, such as a stereoscope, may be mounted to the bench so that images may be captured of a culture without removal of the culture from the incubator.Type: ApplicationFiled: December 12, 2008Publication date: June 17, 2010Inventors: David J. Beebe, Kathryn M. Haubert, Benjamin J. Moga
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Publication number: 20100030156Abstract: A drug delivery platform is provided for delivering a controlled infusion of a drug to an individual. The drug delivery platform includes a reservoir for receiving the drug therein and a hydrogel engageable with the reservoir. The hydrogel is movable between a first configuration and a second configuration wherein the hydrogel exerts a pressure on the reservoir to urge the drug therefrom in response to a predetermined stimulus. A flow guide distributes the predetermined stimulus over the hydrogel in response to activation by an individual.Type: ApplicationFiled: August 1, 2008Publication date: February 4, 2010Inventors: David J. Beebe, Benjamin J. Moga, Tony Escarcega, Kent Chase
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Publication number: 20100030198Abstract: A drug delivery platform is provided for delivering a controlled infusion of a drug to an individual. The drug delivery platform includes a reservoir for receiving the drug therein and a pressure source engageable with the reservoir. The pressure source is movable between a first configuration and a second configuration wherein the pressure source exerts a pressure on the reservoir to urge the drug therefrom. An output conduit is provided for transmitting the drug into the individual. An actuation mechanism is operatively connected to the pressure source and the output conduit. The actuation mechanism is movable between a non-actuated position and an actuated position wherein pressure source moves from the first configuration to the second configuration and wherein the input of the output conduit communicates with the drug and the output end of the output conduit is receivable in the individual.Type: ApplicationFiled: August 1, 2008Publication date: February 4, 2010Inventors: David J. Beebe, Benjamin J. Moga, Tony Escarcega, Kent Chase
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Patent number: D619245Type: GrantFiled: January 8, 2010Date of Patent: July 6, 2010Assignees: Ratio, Inc., FluGen, Inc.Inventors: Benjamin J. Moga, Kent B. Chase, Garrick D. S. Smith
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Patent number: D638534Type: GrantFiled: January 8, 2010Date of Patent: May 24, 2011Assignees: Ratio, Inc., FluGen, Inc.Inventors: Benjamin J. Moga, Kent B. Chase, Garrick D. S. Smith