Patents by Inventor Benjamin Julius RAUCH

Benjamin Julius RAUCH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EFFECTOR PROTEINS, EFFECTOR PARTNERS, COMPOSITIONS, SYSTEMS AND METHODS OF USE THEREOF
    Publication number: 20240131187
    Abstract: Provided herein are compositions, systems, and methods comprising effector proteins, effector partners, and uses thereof. These effector proteins may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure may leverage the activities of these effector proteins for the modification, detection, and/or engineering of nucleic acids.
    Type: Application
    Filed: September 17, 2023
    Publication date: April 25, 2024
    Inventors: Timothy Robert ABBOTT, Aaron DELOUGHERY, David PAEZ-ESPINO, Benjamin Julius RAUCH
  • Effector proteins and methods of use
    Patent number: 11814620
    Abstract: Provided herein are compositions, systems, and methods comprising effector proteins and uses thereof. These effector proteins are shown to be active with guide RNAs and may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure leverage the activities of these effector proteins for the modification, detection, and engineering of nucleic acids.
    Type: Grant
    Filed: May 17, 2022
    Date of Patent: November 14, 2023
    Assignee: Mammoth Biosciences, Inc.
    Inventors: Benjamin Julius Rauch, Aaron DeLoughery, William Douglass Wright, David Paez-Espino, Clarissa Oriel Rhines, Lucas Benjamin Harrington, Wiputra Jaya Hartono
  • PROGRAMMABLE NUCLEASES AND METHODS OF USE
    Publication number: 20230357735
    Abstract: Provided herein, in certain embodiments, are programmable nucleases, guide nucleic acids, and complexes thereof. Certain programmable nucleases provided herein comprise a RuvC domain. Also provided herein are nucleic acids encoding said programmable nucleases and guide nucleic acids. Also provided herein are methods of genome editing, methods of regulating gene expression, and methods of detecting nucleic acids with said programmable nucleases and guide nucleic acids.
    Type: Application
    Filed: June 3, 2021
    Publication date: November 9, 2023
    Inventors: Lucas Benjamin HARRINGTON, William Douglass WRIGHT, Pei-Qi LIU, Benjamin Julius RAUCH, Wiputra Jaya HARTONO, Bridget Ann Paine MCKAY, Danuta Sastre PHIPPS, Yuxuan ZHENG, Nerea SANVISENS, Sean CHEN, David PAEZ-ESPINO
  • EFFECTOR PROTEINS AND METHODS OF USE
    Publication number: 20230323406
    Abstract: Provided herein are compositions, systems, and methods comprising effector proteins and uses thereof. These effector proteins are shown to be active with guide RNAs and may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure leverage the activities of these effector proteins for the modification, detection, and engineering of nucleic acids.
    Type: Application
    Filed: June 12, 2023
    Publication date: October 12, 2023
    Inventors: Aaron DELOUGHERY, Matan DRORY RETWITZER, Lucas Benjamin HARRINGTON, Wiputra Jaya HARTONO, Alexander Richard NECKELMANN, David PAEZ-ESPINO, Benjamin Julius RAUCH, Clarissa Oriel RHINES, Stepan TYMOSHENKO, Fnu YUNANDA, William Douglass WRIGHT
  • EFFECTOR PROTEINS AND METHODS OF USE
    Publication number: 20230257739
    Abstract: Provided herein are compositions, systems, and methods comprising effector proteins and uses thereof. These effector proteins are shown to be active with guide RNAs and may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure leverage the activities of these effector proteins for the modification, detection, and engineering of nucleic acids.
    Type: Application
    Filed: September 23, 2022
    Publication date: August 17, 2023
    Inventors: Aaron DELOUGHERY, David PAEZ-ESPINO, Benjamin Julius RAUCH, Clarissa Oriel RHINES, Stepan TYMOSHENKO, Fnu YUNANDA, Matan DRORY RETWITZER, Lucas Benjamin HARRINGTON, Wiputra Jaya HARTONO, William Douglass WRIGHT, Alexander Richard NECKELMANN
  • EFFECTOR PROTEINS AND METHODS OF USE
    Publication number: 20230203481
    Abstract: Provided herein are compositions, systems, and methods comprising effector proteins and uses thereof. These effector proteins are shown to be active with guide RNAs and may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure leverage the activities of these effector proteins for the modification, detection, and engineering of nucleic acids.
    Type: Application
    Filed: November 7, 2022
    Publication date: June 29, 2023
    Inventors: Rohan GROVER, Clarissa Oriel RHINES, Aaron DELOUGHERY, Benjamin Julius RAUCH, William Douglass WRIGHT, David PAEZ-ESPINO, Lucas Benjamin HARRINGTON
  • PROGRAMMABLE NUCLEASES AND METHODS OF USE
    Publication number: 20230167454
    Abstract: Provided herein, in certain embodiments, are programmable nucleases, guide nucleic acids, and complexes thereof. Certain programmable nucleases provided herein comprise a RuvC domain. Also provided herein are nucleic acids encoding said programmable nucleases and guide nucleic acids. Also provided herein are methods of genome editing, methods of regulating gene expression, and methods of detecting nucleic acids with said programmable nucleases and guide nucleic acids.
    Type: Application
    Filed: August 11, 2022
    Publication date: June 1, 2023
    Inventors: Lucas Benjamin HARRINGTON, William Douglass WRIGHT, Pei-Qi LIU, Benjamin Julius RAUCH, Wiputra Jaya HARTONO, Bridget Ann Paine MCKAY, Danuta Sastre PHIPPS, Yuxuan ZHENG, Nerea SANVISENS, Sean CHEN, David PAEZ-ESPINO
  • EFFECTOR PROTEINS AND METHODS OF USE
    Publication number: 20230068771
    Abstract: Provided herein are compositions, systems, and methods comprising effector proteins and uses thereof. These effector proteins are shown to be active with guide RNAs and may be characterized as CRISPR-associated (Cas) proteins. Various compositions, systems, and methods of the present disclosure leverage the activities of these effector proteins for the modification, detection, and engineering of nucleic acids.
    Type: Application
    Filed: May 17, 2022
    Publication date: March 2, 2023
    Inventors: Benjamin Julius RAUCH, Aaron DELOUGHERY, William Douglass WRIGHT, David PAEZ-ESPINO, Clarissa Oriel RHINES, Lucas Benjamin HARRINGTON, Wiputra Jaya HARTONO