Abstract: The invention relates to tonoplast proton/sugar antiporter proteins, more particularly tonoplast proton/saccharose antiporter proteins, the nucleotide sequences which encode them and uses thereof for producing transgenic plants with an increased saccharose concentration. The invention also includes methods for producing transgenic plants with an increased saccharose concentration, methods for increasing the saccharose concentration in plants, and for identifying plants which are suitable for creating a higher saccharose concentration.

Abstract: Electronic system including an inhaler device for dispensing a medicament formulation in aerosol or dry powder form and an external device which is configured to receive data communicated from the inhaler device. The inhaler device includes a mouthpiece and a flow rate sensor for sensing a flow rate of an inhalation flow which is caused by a patient upon inhalation through the mouthpiece and in which the medicament formulation is entrained or dispensed. The inhaler device further comprises an actuation sensing device having at least one actuation sensor which is configured to sense preparatory steps of the inhaler device in order to prepare a use of the inhaler device and/or to sense the actuation of the inhaler device in order to dispense the medicament formulation. The actuation sensor and the flow rate sensor are configured to generate sensor signals.

Abstract: A technology is described for a certification system for tracking bulk dental material as it becomes a dental restoration. The bulk dental material, such as yttria stabilized zirconia, is used to form multiple different dental restorations. A trackable code is associated with and carried with the bulk dental material. The trackable code is associated with bulk information of the bulk dental material, such as yttria content and source of origin. A plurality of certificates is associated with and carried with the bulk dental material. Each certificate has a different distinguishable code associable with restoration information of a different one of the multiple different dental restorations. Each certificate is separable from the bulk dental material and associable with a different one of the multiple different dental restorations. Each certificate can be a single monolithic certificate with a partition separable into two parts including a dentist part and a patient part.

Abstract: An inhalation system including a metered dose inhaler and a separate computing device. The inhaler includes a flow rate sensor for detecting an inhalation flow through the actuator housing upon patient inhalation and a transmitting unit for transmitting a signal of the at least first switch as well as of the flow rate sensor to the computing device. The computing device generates visual and/or acoustic messages independently of the signals of the at least one switch and the flow rate sensor in order to guide the patient through multiple steps. The computing device further evaluates the use of the inhaler by comparing the transmitted signals of the at least first switch and of the flow rate sensor with the visual and/or acoustic messages. The transmitting unit transmits the signals of the at least first switch and the flow rate sensor to the computing device after the use of the inhaler.

Abstract: An electronic system (1) comprises an electronic device (2) for gathering data from an inhaler (3) which is configured to dispense doses of a pharmaceutical formulation stored in a medicament reservoir. The system (1) further comprises an evaluation unit (9) being configured to receive and evaluate the gathered data in order to determine adherence to prescription data and/or to determine the number of doses having been dispensed or remaining in the inhaler (3) and a display (8) for visualizing the evaluated data. The electronic device (2) comprises a wireless interface (4) for receiving wireless data from the inhaler (3) via a wireless connection an input interface (5) for receiving manual input data and an acoustic or visual interface (6, 7) for receiving acoustic or visual data of the inhaler (3).

Abstract: A consumption unit for an inhaler comprises a liquid reservoir, a vaporizer device arranged in the liquid reservoir, and a vent having a flow channel extending in the liquid reservoir to a flow connection of the flow channel to the environment. The liquid reservoir comprises a filling opening, which is closed by means of a first closure part.

Abstract: The invention relates to tonoplast proton/sugar antiporter proteins, more particularly tonoplast proton/saccharose antiporter proteins, the nucleotide sequences which encode them and uses thereof for producing transgenic plants with an increased saccharose concentration. The invention also includes methods for producing transgenic plants with an increased saccharose concentration, methods for increasing the saccharose concentration in plants, and for identifying plants which are suitable for creating a higher saccharose concentration.

Abstract: The invention relates to a metered dose inhaler (1) for dispensing aerosol doses with an actuation housing (2) and a canister (5) with an aerosol. A triggering unit (8) comprises one single trigger member (21) on a flexible member (22) for activating a switch (19) of a circuit assembly. The flexible member (22) is configured to interact with the canister (5) in such a way that the trigger member (21) is moved in a lateral direction by the canister (5) so that the trigger member (21) engages the switch (19).

Abstract: Electronic system including an inhaler device for dispensing a medicament formulation in aerosol or dry powder form and an external device which is configured to receive data communicated from the inhaler device. The inhaler device includes a mouthpiece and a flow rate sensor for sensing a flow rate of an inhalation flow which is caused by a patient upon inhalation through the mouthpiece and in which the medicament formulation is entrained or dispensed. The inhaler device further comprises an actuation sensing device having at least one actuation sensor which is configured to sense preparatory steps of the inhaler device in order to prepare a use of the inhaler device and/or to sense the actuation of the inhaler device in order to dispense the medicament formulation. The actuation sensor and the flow rate sensor are configured to generate sensor signals.

Abstract: The invention relates to tonoplast proton/sugar antiporter proteins, more particularly tonoplast proton/saccharose antiporter proteins, the nucleotide sequences which encode them and uses thereof for producing transgenic plants with an increased saccharose concentration. The invention also includes methods for producing transgenic plants with an increased saccharose concentration, methods for increasing the saccharose concentration in plants, and for identifying plants which are suitable for creating a higher saccharose concentration.

Abstract: A metered dose inhaler (1) for dispensing aerosol doses comprises an actuation housing (2) adapted to receive a canister (4). The canister (4) is configured to move from a rest position to an activation position in which a valve (7) of the canister (4), positioned at a valve end (8) of the canister (4), is depressed against a bottom portion of the actuation housing such that an aerosol dose is released. The inhaler (1) further comprises a mechanical dose (10) counter comprising an indicator member which is constructed and arrangement to undergo a predetermined count-indicating motion when an aerosol dose is released. Moreover, the inhaler (1) comprises a triggering unit (11) for triggering at least one electrical switch (12) when the canister (4) is moved from the rest position to the activation position whereby an electrical signal is generated. Also part of the inhaler (1) is a processing unit for processing the signal generated by the switch (12) upon being triggered.

Abstract: A computer device for providing evidence of goods delivered and services performed. The computer device can include one or more processors and non-transitory computer-readable media storing computer-readable instructions executable by the one or more processors to perform operations. The operations can include storing video media recorded by a provider, the video media being at least a portion of a performance by a provider providing one of goods and services in the home of a customer, and delivering at least a portion of the video media to the customer. The delivered portion of the video media can be a receipt for the one of goods and services performed.

Abstract: An inhalation system comprising a metered dose inhaler (2) for dispensing an aerosol dose during use and a separate computing device for computing signals received from the metered dose inhaler. The metered dose inhaler (2) comprises a flow rate sensor (16) for detecting an inhalation flow through the actuator housing (4) during use of the metered dose inhaler (2) upon inhalation by a patient and a transmitting unit (20) for transmitting a signal of the at least first switch (10a) as well as of the flow rate sensor (16) to the computing device (3). The computing device (3) is configured to generate visual and/or acoustic messages independently of the signals of the at least one switch (10a) and the flow rate sensor (16) in order to guide the patient through multiple steps of the use of the metered dose inhaler (2).

Abstract: The invention relates to a metered dose inhaler (1) for dispensing aerosol doses with an actuation housing (2) and a canister (5) with an aerosol. A triggering unit (8) comprises one single trigger member (21) on a flexible member (22) for activating a switch (19) of a circuit assembly. The flexible member (22) is configured to interact with the canister (5) in such a way that the trigger member (21) is moved in a lateral direction by the canister (5) so that the trigger member (21) engages the switch (19).

Abstract: A metered dose inhaler (1) for dispensing aerosol doses comprises an actuation housing (2) adapted to receive a canister (4). The canister (4) is configured to move from a rest position to an activation position in which a valve (7) of the canister (4), positioned at a valve end (8) of the canister (4), is depressed against a bottom portion of the actuation housing such that an aerosol dose is released. The inhaler (1) further comprises a mechanical dose (10) counter comprising an indicator member which is constructed and arrangement to undergo a predetermined count-indicating motion when an aerosol dose is released. Moreover, the inhaler (1) comprises a triggering unit (11) for triggering at least one electrical switch (12) when the canister (4) is moved from the rest position to the activation position whereby an electrical signal is generated. Also part of the inhaler (1) is a processing unit for processing the signal generated by the switch (12) upon being triggered.

Abstract: The invention relates to tonoplast proton/sugar antiporter proteins, more particularly tonoplast proton/saccharose antiporter proteins, the nucleotide sequences which encode them and uses thereof for producing transgenic plants with an increased saccharose concentration. The invention also includes methods for producing transgenic plants with an increased saccharose concentration, methods for increasing the saccharose concentration in plants, and for identifying plants which are suitable for creating a higher saccharose concentration.

Abstract: A method for noninvasive on-line secondary path modeling for the filtered-X LMS algorithm actively controls periodic noise. The method, based in the frequency domain, uses the concept of linear independence of two equations/two unknowns to arrive at the secondary path estimate. Linear independence of the two equations is achieved by adjusting the control filter output via the filter coefficients prior to the acquisition of the second set of data corresponding to the second equation.

Abstract: A method for noninvasive on-line secondary path modeling for the filtered-X LMS algorithm actively controls periodic noise. The method, based in the frequency domain, uses the concept of linear independence of two equations/two unknowns to arrive at the secondary path estimate. Linear independence of the two equations is achieved by adjusting the control filter output via the filter coefficients prior to the acquisition of the second set of data corresponding to the second equation.