Patents by Inventor BENJAMIN K. ESTEP

BENJAMIN K. ESTEP has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PEPTIDE AMPHIPHILES WITH MODIFIED DEGRADING SEQUENCES AND METHODS OF USE THEREOF
    Publication number: 20240218017
    Abstract: Disclosed are peptide amphiphiles comprising a hydrophilic peptide sequence and a hydrophobic tail, wherein the hydrophobic tail comprises a moiety having a substituted C16 alkyl chain, wherein the hydrophilic peptide sequence comprises a degrading sequence (DS), wherein the degrading sequence (DS) comprises the amino acid sequence GTAGLIGQ (SEQ ID NO:1) wherein the DS comprises one or more amino acid substitutions. Also disclosed are compositions, liposomes, gels, and medical devices comprising the peptide amphiphiles and methods of use thereof.
    Type: Application
    Filed: October 6, 2023
    Publication date: July 4, 2024
    Inventors: HO-WOOK JUN, BRIGITTA BROTT, XIXI ZHANG, JUN CHEN, BENJAMIN K. ESTEP, JENNIFER SHERWOOD, PATRICK HWANG