Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.

Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.

Abstract: An apparatus for measuring a performance metric of a heart includes a housing, a tactile sensor, a finger clamp, a linear actuator, and a controller. The tactile sensor measures blood pressure pulsatility in a digital artery of a finger via applanation tonometry and outputs pulsatility signals indicative of the blood pressure pulsatility. The finger clamp extends from the housing to clamp the finger against the tactile sensor with the digital artery aligned over the tactile sensor. The linear actuator drives the finger clamp with a clamping force directed along a linear path. The controller is coupled to the tactile sensor and the linear actuator to control the clamping force and to generate pulsatility data, based upon the pulsatility signals, from which the performance metric of the heart may be determined.

Abstract: The present disclosure relates to mapping catheters, and in particular to mapping catheters having thin film electrodes used in sensing electrical activity within a patient. Particularly, aspects of the present disclosure are directed to a medical device having a hollow core, a balloon disposed over at least a portion of the hollow core, and a flexible framework having one or more thin film elements formed on at least a portion of the balloon. The one or more thin film elements comprise a plurality of mapping electrodes.

Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a main body, a first plug extending from the main body, a flexible bridge extending from the main body or the first plug, and a second plug extending from the flexible bridge. This structure allows for the main body, the first plug, and the second plug to be arranged in tandem on a longitudinal axis of the main body, which enables the connector to be passed through a narrow diameter cannula. This structure also allows for the first plug and the second plug to be arranged in a spread out orientation, which enables the connector to be electrically connected with a neurostimulator.

Abstract: Provided is a biomonitoring device that measures a parameter of a material expelled during use of a toilet by a user. Also provided is a biomonitoring mirror device that identifies a user, detects a febrile illness in a user, dispenses medications/supplements, connects to electrical device accessories in the bathroom, and provides an interactive user interface. Additionally provided is a system for measuring a parameter of a material expelled during use of a toilet by a user. Further provided is a method of determining a physiological parameter of a user.

Abstract: The present disclosure relates to connectors for high density neural interfaces and methods of microfabricating the connectors. Particularly, aspects of the present disclosure are directed to a connector having a core and a supporting structure wrapped around at least a portion of the core. The supporting structure may have a first layer of a high temperature liquid crystal polymer, and the second layer of a low temperature liquid crystal polymer that is reflowed to attach the supporting structure to the core. Conductive traces are buried between the first layer and the second layer, and the conductive traces terminate at conductive contacts formed on a surface of the first layer. The connector may have a predetermined shape or profile, which facilitates alignment and insertion of the connector into a header of a neurostimulator.

Abstract: Provided is a biomonitoring device that measures a parameter of a material expelled during use of a toilet by a user. Also provided is a biomonitoring mirror device that identifies a user, detects a febrile illness in a user, dispenses medications/supplements, connects to electrical device accessories in the bathroom, and provides an interactive user interface. Additionally provided is a system for measuring a parameter of a material expelled during use of a toilet by a user. Further provided is a method of determining a physiological parameter of a user.

Abstract: A method of surgical dissection of tissue with a dissector comprising: an elongate shaft comprising a proximal portion and a distal portion, wherein the distal portion comprises a plurality of segments that articulate with respect to one another and the plurality of segments includes a distal segment having a distal end; and a handle attached to the proximal portion of the shaft, wherein the handle comprises controls for articulating the plurality of segments of the distal portion of the shaft with respect to one another, comprising the steps of: positioning the distal end of the dissector in a body; advancing the distal end through the body to dissect tissue; and simultaneously articulating the plurality of segments with respect to one another. A method of surgical dissection of tissue and guiding a second device to a desired physiological location with a first device.

Abstract: The present disclosure relates to laparoscopic surgery, and in particular to laparoscopic ports for facilitating the implant of medical systems such as a neuromodulation system into the body of a patient. Particularly, aspects are directed to a cannula assembly having a cannula housing and a cannula sleeve comprising a sleeve body extending from a distal end of the cannula housing. The cannula sleeve has a semi-rectangular cross section including: (i) a rounded rectangular portion configured to accommodate feeding the neuromodulation system through the cannula assembly, and (ii) a circular portion configured to accommodate insertion of the one or more surgical instruments through the cannula assembly.

Abstract: The present disclosure relates to laparoscopic surgery, and in particular to laparoscopic ports for facilitating the implant of medical systems such as a neuromodulation system into the body of a patient. Particularly, aspects are directed to a cannula assembly having a cannula housing and a cannula sleeve comprising a sleeve body extending from a distal end of the cannula housing. The cannula sleeve has a semi-rectangular cross section including: (i) a rounded rectangular portion configured to accommodate feeding the neuromodulation system through the cannula assembly, and (ii) a circular portion configured to accommodate insertion of the one or more surgical instruments through the cannula assembly.

Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.

Abstract: The present disclosure relates to devices and methods for partly isolating a target biological structure. The device may include a main body comprising a front face and a rear face, the main body having a proximal end and a distal end. The distal end may be arcuate in a first state and may be substantially planar in a second state. The device may further include one or more balloons disposed on the distal end of the main body. Each of the one or more balloons is deflated in the first state and each of the one or more balloons is inflated in the second state. The distal end of the main body is configured to deform to be substantially planar when each of the one or more balloons are inflated in the second state.

Abstract: The present disclosure relates to devices and methods for partly isolating a target biological structure. The device may include a main body comprising a front face and a rear face, the main body having a proximal end and a distal end. The distal end may be arcuate in a first state and may be substantially planar in a second state. The device may further include one or more balloons disposed on the distal end of the main body. Each of the one or more balloons is deflated in the first state and each of the one or more balloons is inflated in the second state. The distal end of the main body is configured to deform to be substantially planar when each of the one or more balloons are inflated in the second state.

Abstract: Dispensing devices and systems for oral transmucosal administration of small volume drug dosage forms to the oral mucosa are provided. The dispensing device may be a single dose applicator (SDA), or an electromechanical device comprising a means for patient identification such as a wrist worn RFID tag and annular bidirectional antenna together with a lock-out feature.

Abstract: The present disclosure relates to a method for installing a cuff around a target biological structure. The method may include inserting a guidewire through an incision in a patient underneath an exterior surface of a target biological structure, guiding a ramp device over the guidewire to a position underneath the target biological structure such that the target biological structure is partly supported by the ramp device, guiding a cuff deployment tool over the guidewire to the ramp device, the cuff deployment tool comprising an interior volume and a cuff positioned within the interior volume, and causing the cuff from the cuff deployment tool to deploy such that the cuff moves from within the interior volume to an extended position. At least part of the cuff is positioned between the ramp device and the target biological structure in the extended position.

Abstract: An access device places a medical article within a body space of a patient. The device has a needle that includes an elongated body and a needle hub. The device further includes a dilator disposed on and slideable along the elongated body of the needle and a medical article. The medical article is disposed on and slideable along the dilator. A track extends in a proximal direction from the dilator. The needle hub slides along at least a portion of the track between a first position and a second position. The device further includes a locking mechanism operably disposed between the track and the needle hub so as to inhibit further axial movement of the needle in the proximal direction when the needle hub is in the second position.

Abstract: An access device places a medical article within a body space of a patient. The device has a needle that includes an elongated body and a needle hub. The device further includes a dilator disposed on and slideable along the elongated body of the needle and a medical article. The medical article is disposed on and slideable along the dilator. A track extends in a proximal direction from the dilator. The needle hub slides along at least a portion of the track between a first position and a second position. The device further includes a locking mechanism operably disposed between the track and the needle hub so as to inhibit further axial movement of the needle in the proximal direction when the needle hub is in the second position.

Abstract: An access device places a medical article within a body space of a patient. The device has a needle section that includes an elongated body and a needle hub. The device further includes a dilator portion that has a dilator and a dilator hub. The dilator is coaxially disposed and slideable over the elongated body of the needle section. The device further includes a sheath section that has a sheath and a sheath hub. The sheath is coaxially disposed and slideable over the dilator. The device further includes a first locking mechanism operably disposed between the needle hub and the dilator hub to inhibit at least unintentional axial movement between the needle section and the dilator portion and a second locking mechanism operably disposed between the dilator hub and the sheath hub to inhibit at least unintentional axial movement between the dilator portion and the sheath section.