Abstract: Systems, methods, and media for multiple beam optical coherence tomography are provided which, in some embodiments, include: a light source; a splitter that outputs a fraction of light to various waveguides; optical components that receive light from the waveguides and direct the light as beams that simultaneously impinge a sample at different lateral positions, and collect backscattered light from the lateral positons; another splitter that outputs a fraction of light to waveguides of a reference arm as reference light samples; a mixer that receives the backscattered light samples and the reference light samples, and combines each backscattered sample with a corresponding reference sample such that the mixer outputs fringes; and a detector that receives the fringes, and outputs OCT signals, each indicative of a structure of the sample at a respective lateral position.

Abstract: A method of forming a crystalline core/crystalline clad (C4) optical fiber. The method comprises coextruding a cladding mixture of a plasticizer and a binder with a yttrium aluminum garnet (YAG) core. The coextrusion dynamically clads a polycrystalline cladding onto the YAG core to yield a green C4 optical fiber. The C4 optical fiber is then densified, preferably in two steps sintering and hot isostatic pressing. The resulting optical C4 fiber has greater power capacity than a glass fiber labor host.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a system includes a display and a controller. The display includes: a backplane having a plurality of circuits and a plurality of display elements arranged on the backplane. The plurality of display elements form an irregular pattern. Each of the plurality of display elements is coupled to a respective circuit of the plurality of circuits. The controller is coupled to the display and configured to transmit at least one control signal to at least one display element of the display for modulating at least one property of the at least one display element.

Abstract: A tri-layer optical fiber. The fiber has a core which is preferably a single crystal and outer cladding, to reduce signal loss. The cladding process begins with high porosity particles, and is known to introduce porosity in the cladding and at the core/cladding interface. The porosity increases refraction and signal loss. The invention interposes a film layer intermediate the core and cladding. The film layer is sputter coated and preferably of the of same material as the cladding. The film prevents diffusion of the porous cladding into the core, minimizing porosity and improving signal transmission.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, an optical device includes: an optical guiding device configured to guide light to propagate along a first direction within the optical guiding device; an in-coupling diffractive structure configured to diffract the light to propagate in the optical guiding device; and out-coupling diffractive structures configured to diffract at least part of the light out of the optical guiding device along a second direction different from the first direction. The out-coupling diffractive structures are configured to have gradually increased diffraction efficiencies for the light along the first direction away from the in-coupling diffractive structure.

Abstract: Systems, methods, and media for multiple beam optical coherence tomography are provided which, in some embodiments, include: a light source; a splitter that outputs a fraction of light to various waveguides; optical components that receive light from the waveguides and direct the light as beams that simultaneously impinge a sample at different lateral positions, and collect backscattered light from the lateral positons; another splitter that outputs a fraction of light to waveguides of a reference arm as reference light samples; a mixer that receives the backscattered light samples and the reference light samples, and combines each backscattered sample with a corresponding reference sample such that the mixer outputs fringes; and a detector that receives the fringes, and outputs OCT signals, each indicative of a structure of the sample at a respective lateral position.

Abstract: The present disclosure is drawn to compositions and methods for treating CNS disorders. In one embodiment, an oral pharmaceutical composition can comprise a therapeutically effective amount of pregn-4-ene-3,20-dione; and a pharmaceutically acceptable carrier that provides formation of either 3?-OH-5?-pregnan-20-one, or 3?-OH-5?-pregnan-20-one, or both in an amount sufficient to treat a CNS disorder when orally administered to a subject. In another embodiment, a method of treating a CNS disorder can comprise orally administering to a subject, a therapeutically effective amount of pregn-4-ene-3,20-dione that provides an amount of GABA receptor binding pregn-4-ene-3,20-dione metabolites that is sufficient to treat the CNS disorder.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a system includes: a display having a plurality of display elements and a driving device coupled to the driving device and configured to: obtain a hologram for the display, wherein the hologram comprises, for each display element of the plurality of display elements, a respective sum of electromagnetic (EM) field contributions of a plurality of primitives corresponding to at least one object to the display element; and generate, for each display element of the plurality of display elements, a respective modulation control signal based on the respective sum of EM field contributions of the plurality of primitives to the display element.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a system includes a display and a controller. The display includes: a backplane having a plurality of circuits and a plurality of display elements arranged on the backplane. The plurality of display elements form an irregular pattern. Each of the plurality of display elements is coupled to a respective circuit of the plurality of circuits. The controller is coupled to the display and configured to transmit at least one control signal to at least one display element of the display for modulating at least one property of the at least one display element.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a system includes a display and a controller. The display includes: a backplane having a plurality of circuits and a plurality of display elements arranged on the backplane. The plurality of display elements form an irregular pattern. Each of the plurality of display elements is coupled to a respective circuit of the plurality of circuits. The controller is coupled to the display and configured to transmit at least one control signal to at least one display element of the display for modulating at least one property of the at least one display element.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a system includes a display and a controller. The display includes: a backplane having a plurality of circuits and a plurality of display elements arranged on the backplane. The plurality of display elements form an irregular pattern. Each of the plurality of display elements is coupled to a respective circuit of the plurality of circuits. The controller is coupled to the display and configured to transmit at least one control signal to at least one display element of the display for modulating at least one property of the at least one display element.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a system includes a display and a controller. The display includes: a backplane having a plurality of circuits and a plurality of display elements arranged on the backplane. The plurality of display elements form an irregular pattern. Each of the plurality of display elements is coupled to a respective circuit of the plurality of circuits. The controller is coupled to the display and configured to transmit at least one control signal to at least one display element of the display for modulating at least one property of the at least one display element.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a computer-implemented method of manipulating data of a plurality of primitives corresponding to at least one object includes: for each of a plurality of vertices of the plurality of primitives, associating a respective vertex identifier of the vertex with respective vertex data of the vertex, and storing the association between the respective vertex identifier and the respective vertex data of the vertex in a memory; and for each of the plurality of primitives, associating a respective primitive identifier of the primitive with one or more respective vertex identifiers of one or more vertices of the primitive in the memory, and storing an association between the respective primitive identifier and the one or more respective vertex identifiers for the primitive in the memory.

Abstract: Methods, apparatus, devices, subsystems, and systems for holographically displaying three-dimensional objects are provided. In one aspect, a system includes a display and a controller. The display includes: a backplane having a plurality of circuits and a plurality of display elements arranged on the backplane. The plurality of display elements form an irregular pattern. Each of the plurality of display elements is coupled to a respective circuit of the plurality of circuits. The controller is coupled to the display and configured to transmit at least one control signal to at least one display element of the display for modulating at least one property of the at least one display element.

Abstract: Systems and methods are presented for detecting users within a range of a media device. A detection region may be defined that is within the range of the media device and smaller than the range. The detection region may be stored. It may be determined whether a user is within the detection region. The media device may be activated and settings associated with the user may be applied when a user is within the detection region. In some embodiments, settings associated with a user may be compared to provided media content when the user is within the detection region. The content may change when the settings conflict with the media content. Reminders may be provided to or directed to a plurality of users within the range of the media device.

Abstract: Systems and methods are presented for detecting users within a range of a media device. A detection region may be defined that is within the range of the media device and smaller than the range. The detection region may be stored. It may be determined whether a user is within the detection region. The media device may be activated and settings associated with the user may be applied when a user is within the detection region. In some embodiments, settings associated with a user may be compared to provided media content when the user is within the detection region. The content may change when the settings conflict with the media content. Reminders may be provided to or directed to a plurality of users within the range of the media device.

Abstract: Systems and related methods of providing seamless transactions, including payments and promotion redemptions, are discussed herein. Some embodiments may provide for a system including a communication beacon and one or more servers. The communication beacon may be configured to communicate with consumer devices via a direct wireless connection when the consumer devices are within a wireless direct communicable range of the communication beacon. The one or more servers may be configured to associate the communication with a merchant and receive consumer presence data from the communication beacon such that consumer presence at the merchant may be determined. In response, the one or more servers may be configured to perform a seamless transaction on behalf the consumer that allows the consumer to provide payments or redeem promotions, among other things, simply by self-identifying with the merchant while carrying the consumer device.

Abstract: Systems and related methods of providing seamless transactions, including payments and promotion redemptions, are discussed herein. Some embodiments may provide for a system including a communication beacon and one or more servers. The communication beacon may be configured to communicate with consumer devices via a direct wireless connection when the consumer devices are within a wireless direct communicable range of the communication beacon. The one or more servers may be configured to associate the communication with a merchant and receive consumer presence data from the communication beacon such that consumer presence at the merchant may be determined. In response, the one or more servers may be configured to perform a seamless transaction on behalf the consumer that allows the consumer to provide payments or redeem promotions, among other things, simply by self-identifying with the merchant while carrying the consumer device.

Abstract: Systems and related methods of providing promotions to consumers based on proximity to communication beacons are discussed herein. Some embodiments may provide for a system including a communication beacon and a central system. The communication beacon may be associated with a merchant and located at a merchant shop. Based on receiving consumer presence data from the communication beacon indicating that a consumer device and the communication beacon has formed a direct wireless connection, the server may be configured to provide merchant information, promotions, or other messages to the consumer device. In some embodiments, messages may be generated by the merchant and targeted to consumers based on consumer device location, consumer demographics, among other things. Furthermore, the server may provide consumer information to a merchant device to facilitate consumer service, point-of-sale, and seamless transactions and promotion redemptions.

Abstract: Systems and methods are presented for detecting users within a range of a media device. A detection region may be defined that is within the range of the media device and smaller than the range. The detection region may be stored. It may be determined whether a user is within the detection region. The media device may be activated and settings associated with the user may be applied when a user is within the detection region. In some embodiments, settings associated with a user may be compared to provided media content when the user is within the detection region. The content may change when the settings conflict with the media content. Reminders may be provided to or directed to a plurality of users within the range of the media device.