Abstract: A catheter stabilization device for stabilizing an inserted catheter penetrating a surface at a catheter insertion site, including: a base that is coupleable to the surface and includes a channel defining a longitudinal opening that receives a portion of the catheter, and a frame that forms at least a partial perimeter around the catheter insertion site with a plurality of anchoring points; and a catheter fitting, coupled to the base, that secures the catheter in the channel. The base couples to the surface at the plurality of anchoring points distributed around the catheter insertion site, thereby stabilizing the catheter. The method of using the device includes positioning the base over the catheter, receiving a portion of the catheter in the channel through the longitudinal opening, securing the catheter within the channel, and coupling the base to the surface at the plurality of anchoring points distributed around the insertion site.