Abstract: In part, the present disclosure relates methods for treating heterotopic ossification or one or more complications of heterotopic ossification. In particular, the disclosure provided methods for treating heterotopic ossification by administering to a patient in need thereof one or more TGF? antagonists, optionally in combination with one or more additional active agents or supportive therapies for treating heterotopic ossification. For example, in some embodiments, the disclosure provided methods for treating heterotopic ossifications by administering to a patient in need thereof an effective amount of a T?RII polypeptide.

Abstract: A short wave infrared (SWIR) imaging system and method of using the same is provided for assessing a tissue damage depth and/or readiness for reconstruction and/or debridement. The SWIR imaging system includes a light source for illuminating the wound or burn, an image light-registering camera system having at least one narrow-band SWIR filter to image the wound or burn and output imaging information, and a detection system for receiving the imaging information and processing the imaging information to determine a tissue damage depth and/or readiness for reconstruction and/or debridement assessment.

Abstract: In part, the present disclosure relates methods for treating heterotopic ossification or one or more complications of heterotopic ossification. In particular, the disclosure provided methods for treating heterotopic ossification by administering to a patient in need thereof one or more TGF? antagonists, optionally in combination with one or more additional active agents or supportive therapies for treating heterotopic ossification. For example, in some embodiments, the disclosure provided methods for treating heterotopic ossifications by administering to a patient in need thereof an effective amount of a T?RII polypeptide.

Abstract: The invention provides a method of treating heterotopic ossification in a subject in need thereof. The method comprises administering a hypoxia inducible factor-1? (Hif-1?) inhibitor to the subject. In various embodiments, the Hif-1? inhibitor is PX-478, rapamycin, or digoxin.

Abstract: The invention is a wearable breast pump system including a housing shaped at least in part to fit inside a bra and a piezo air-pump. The piezo air-pump is fitted in the housing and forms part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm is removably mounted on a breast shield.

Abstract: A short wave infrared (SWIR) imaging system and method of using the same is provided for assessing a tissue damage depth and/or readiness for reconstruction and/or debridement. The SWIR imaging system includes a light source for illuminating the wound or burn, an image light-registering camera system having at least one narrow-band SWIR filter to image the wound or burn and output imaging information, and a detection system for receiving the imaging information and processing the imaging information to determine a tissue damage depth and/or readiness for reconstruction and/or debridement assessment.

Abstract: The invention provides a method of treating heterotopic ossification in a subject in need thereof. The method comprises administering a hypoxia inducible factor-1? (Hif-1?) inhibitor to the subject. In various embodiments, the Hif-1? inhibitor is PX-478, rapamycin, or digoxin.

Abstract: The invention provides a method of treating heterotopic ossification in a subject in need thereof. The method comprises administering a hypoxia inducible factor-1? (Hif-1?) inhibitor to the subject. In various embodiments, the Hif-1? inhibitor is PX-478, rapamycin, or digoxin.

Abstract: The presently disclosed subject matter includes a method, apparatus and computer storage device for reducing dispersion of a rocket caused by jet-stream misalignment, the rocket comprising a rocket engine. Information indicative of a division of total operation time of the rocket engine into a first time period and a second time period is obtained; wherein an impulse which is generated during the first time period is at least approximately the same as an impulse generated during the second time period; a period of time which equals to the first time period starting from time of activation of the rocket engine is measured; upon termination of the period of time, the rocket is rotated around the rocket's longitudinal axis; and the angle of rotation measured; and the rotation is stopped once a 180° rotation is completed.

Abstract: Systems and methods for managing a network are described. A view of current state of the network is maintained where the current state of the network characterizes network topology and network constituents, including network entities and network elements residing in or on the network. Events are announced that correspond to changes in the state of the network and one or more network elements can be configured accordingly. Methods for managing network traffic are described that ensure forwarding and other actions taken by network elements implement globally declared network policy and refer to high-level names, independently of network topology and the location of network constituents. Methods for discovering network constituents are described, whereby are automatically configured. Routing may be performed using ACL and packets can be intercepted to permit host to continue in sleep mode. The methods are applicable to virtual environments.

Abstract: The presently disclosed subject matter includes a laser system and a respective method of detecting a signal reflected from a target illuminated by a modulated CW light source configured to generate a modulated laser signal at a predefined modulation frequency. A signal comprising true laser signal portions reflected from said target, and noise is received; the signal is filtered for selecting laser signal portions at a modulation frequency band; and the true signal portions in the signal are detected, if the energy at the modulation frequency band is greater than a given threshold.

Abstract: The present disclosure provides methods to transfer a pressurized slurry of plant-based biomass into a reactor vessel. The methods allow for the transfer of practical-sized pieces of biomass in a slurry pressurized to above about 300 psi.

Abstract: The invention provides a method of treating heterotopic ossification in a subject in need thereof. The method comprises administering a hypoxia inducible factor-1? (Hif-1?) inhibitor to the subject. In various embodiments, the Hif-1? inhibitor is PX-478, rapamycin, or digoxin.

Abstract: Systems and methods for managing a network are described. A view of current state of the network is maintained where the current state of the network characterizes network topology and network constituents, including network entities and network elements residing in or on the network. Events are announced that correspond to changes in the state of the network and one or more network elements can be configured accordingly. Methods for managing network traffic are described that ensure forwarding and other actions taken by network elements implement globally declared network policy and refer to high-level names, independently of network topology and the location of network constituents. Methods for discovering network constituents are described, whereby are automatically configured. Routing may be performed using ACL and packets can be intercepted to permit host to continue in sleep mode. The methods are applicable to virtual environments.

Abstract: Provided herein is technology relating to compositions comprising apyrase and particularly, but not exclusively, to compositions comprising apyrase, methods of treating with apyrase, and uses of apyrase related to treating a subject, e.g., a subject suffering from a microbial infection, a subject who has a wound or burn and is in need of an antimicrobial treatment, and/or a subject in need of treatment for heterotopic ossification.

Abstract: The presently disclosed subject matter includes a method and system for enabling detection of signal reflection from a target designated by a pulse laser spot generated by a low-power laser designator. A signal comprising true signal portions reflected from said target and noise is received and sampled and a first value or a second value is assigned to each sample. The assigned (ith) values in K pulse rate intervals are summed to obtain respective summed values. One or more candidate clusters are identified from among the summed values and a final candidate cluster is selected from among said one or more candidate clusters. The final candidate cluster is located with respective samples of an incoming pulse rate interval, thereby detecting an area within said signal which comprises the true signal portions.

Abstract: Systems and methods for managing a network are described. A view of current state of the network is maintained where the current state of the network characterizes network topology and network constituents, including network entities and network elements residing in or on the network. Events are announced that correspond to changes in the state of the network and one or more network elements can be configured accordingly. Methods for managing network traffic are described that ensure forwarding and other actions taken by network elements implement globally declared network policy and refer to high-level names, independently of network topology and the location of network constituents. Methods for discovering network constituents are described, whereby are automatically configured. Routing may be performed using ACL and packets can be intercepted to permit host to continue in sleep mode. The methods are applicable to virtual environments.

Abstract: In general, the present invention relates to a virtual platform in which one or more distributed virtual switches can be created for use in virtual networking. According to some aspects, the distributed virtual switch according to the invention provides the ability for virtual and physical machines to more readily, securely, and efficiently communicate with each other even if they are not located on the same physical host and/or in the same subnet or VLAN. According other aspects, the distributed virtual switches of the invention can support integration with traditional IP networks and support sophisticated IP technologies including NAT functionality, stateful firewalling, and notifying the IP network of workload migration. According to further aspects, the virtual platform of the invention creates one or more distributed virtual switches which may be allocated to a tenant, application, or other entity requiring isolation and/or independent configuration state.

Abstract: The present disclosure provides methods to transfer a pressurized slurry of plant-based biomass into a reactor vessel. The methods allow for the transfer of practical-sized pieces of biomass in a slurry pressurized to above about 300 psi.

Abstract: A projectile (100) is provided for operating at least in a launch phase and in a post-launch phase. The projectile includes a projectile body (10), a projectile head (50), and a support structure (80). The projectile head is non-rigidly mounted to the projectile body via a joint structure (70). The support structure is configured for selectively supporting the projectile head with respect to the projectile body in a load bearing relationship independently of the joint structure during at least a portion of the launch phase, and for selectively terminating the support during at least a portion of the post-launch phase. A method for operating a projectile and a method for retrofitting a projectile are also provided.