Patents by Inventor BENJAMIN LIOU

BENJAMIN LIOU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL PHARMACOLOGICAL THERAPY FOR NEURONOPATHIC GAUCHER DISEASE
    Publication number: 20200345808
    Abstract: The instant disclosure relates to methods and compositions for the treatment of Gaucher disease, particularly type II and III neuronopathic Gaucher disease (nGD). The methods include the step of administering to an individual in need thereof an effective amount of a ryanodine receptor inhibitor or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: July 20, 2020
    Publication date: November 5, 2020
    Inventors: Ying Sun, Benjamin Liou
  • Pharmacological therapy for neuronopathic Gaucher disease
    Patent number: 10751387
    Abstract: The instant disclosure relates to methods and compositions for the treatment of Gaucher disease, particularly type II and III neuronopathic Gaucher disease (nGD). The methods include the step of administering to an individual in need thereof an effective amount of a ryanodine receptor inhibitor or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: August 25, 2020
    Assignee: Children's Hospital Medical Center
    Inventors: Ying Sun, Benjamin Liou
  • NOVEL PHARMACOLOGICAL THERAPY FOR NEURONOPATHIC GAUCHER DISEASE
    Publication number: 20170319651
    Abstract: The instant disclosure relates to methods and compositions for the treatment of Gaucher disease, particularly type II and III neuronopathic Gaucher disease (nGD). The methods include the step of administering to an individual in need thereof an effective amount of a ryanodine receptor inhibitor or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 26, 2017
    Publication date: November 9, 2017
    Inventors: Ying Sun, Benjamin Liou
  • Lysosomal protein targeting sequence and therapeutic applications of same
    Patent number: 9738880
    Abstract: The present disclosure relates to methods of treating diseases states such as lysosomal storage diseases and/or neurodegenerative diseases. Also disclosed are one or more compositions that may be useful for one or more of the disclosed methods, including compositions that may comprise acid ?-glucosidase (GCase) protein comprising one or more mutations, peptides of acid ?-glucosidase, and DNA vectors and cell lines related to acid ?-glucosidase peptides or proteins.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: August 22, 2017
    Assignee: Children's Hospital Medical Center
    Inventors: Gregory A. Grabowski, Benjamin Liou
  • LYSOSOMAL PROTEIN TARGETING SEQUENCE AND THERAPEUTIC APPLICATIONS OF SAME
    Publication number: 20170114335
    Abstract: The present disclosure relates to methods of treating diseases states such as lysosomal storage diseases and/or neurodegenerative diseases. Also disclosed are one or more compositions that may be useful for one or more of the disclosed methods, including compositions that may comprise acid ?-glucosidase (GCase) protein comprising one or more mutations, peptides of acid ?-glucosidase, and DNA vectors and cell lines related to acid ?-glucosidase peptides or proteins.
    Type: Application
    Filed: January 5, 2017
    Publication date: April 27, 2017
    Inventors: Gregory A. Grabowski, Benjamin Liou
  • Lysosomal protein targeting sequence and therapeutic applications of same
    Patent number: 9574184
    Abstract: The present disclosure relates to methods of treating diseases states such as lysosomal storage diseases and/or neurodegenerative diseases. Also disclosed are one or more compositions that may be useful for one or more of the disclosed methods, including compositions that may comprise acid ?-glucosidase (GCase) protein comprising one or more mutations, peptides of acid ?-glucosidase, and DNA vectors and cell lines related to acid ?-glucosidase peptides or proteins.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: February 21, 2017
    Assignee: Children's Hospital Medical Center
    Inventors: Gregory A. Grabowski, Benjamin Liou
  • LYSOSOMAL PROTEIN TARGETING SEQUENCE AND THERAPEUTIC APPLICATIONS OF SAME
    Publication number: 20160237414
    Abstract: The present disclosure relates to methods of treating diseases states such as lysosomal storage diseases and/or neurodegenerative diseases. Also disclosed are one or more compositions that may be useful for one or more of the disclosed methods, including compositions that may comprise acid ?-glucosidase (GCase) protein comprising one or more mutations, peptides of acid ?-glucosidase, and DNA vectors and cell lines related to acid ?-glucosidase peptides or proteins.
    Type: Application
    Filed: September 23, 2014
    Publication date: August 18, 2016
    Inventors: GREGORY A. GRABOWSKI, BENJAMIN LIOU