Abstract: Systems and methods for monitoring blood products using portable storage units (“PSUs”) are disclosed. A PSU can be configured to communicate with a blood product management server for monitoring blood products. In many embodiments, a PSU can include a cooling mechanism to control the internal temperature of the PSU, a RFID reader configured to scan at least one RFID tag associated with at least one blood product, a processor, and a memory containing a PSU application, wherein the PSU application configures the processor to: determine a temperature profile for the at least one blood product, generate health status information for the at least one blood product based upon the blood product's temperature profile, generate a user interface that includes information regarding the at least one blood product's health status information, and transmit the at least one blood product's health status information to the blood product management server.