Patents by Inventor Benjamin MAISER

Benjamin MAISER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR TRANSFERRING A BATCH PRODUCTION PROCESS TO A CONTINUOUS PRODUCTION PROCESS
    Publication number: 20220073560
    Abstract: Described herein is a method for transferring of batch production process for a monoclonal antibody to a continuous production process for the same monoclonal antibody.
    Type: Application
    Filed: January 8, 2020
    Publication date: March 10, 2022
    Applicant: Bayer Aktiengesellschaft
    Inventors: Bastian BUDDE, Peter SCHWAN, Sven-Oliver BORCHERT, Benjamin MAISER, Sven CLASSEN, Jürgen LENZ, Laura DAVID, Martin LOBEDANN
  • Validation of continuous viral clearance
    Patent number: 10894991
    Abstract: Disclosed herein is a method for validation of continuous viral clearance comprising the steps of providing a probe to be validated, spiking the probe in a valid manner, performing viral clearance, sampling the spiked probe and analyzing the sample of the spiked probe of step d).
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: January 19, 2021
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Benjamin Maiser, Peter Schwan, Laura David, Martin Lobedann
  • Modular system and process for the continuous, microbe-reduced production and/or processing of a product
    Patent number: 10696940
    Abstract: The invention provides a method for the continuous, microbe-reduced production and/or processing of a biopharmaceutical, biological macromolecular product from a heterogeneous cell culture-fluid mixture, comprising the steps of: (a) providing a particle-free fluid from a heterogeneous cell culture-fluid mixture containing the product, in the form of a product stream, (b) at least one filtration, providing a filtrate, (c) at least two chromatography steps for purifying the product, (d) at least one virus depletion, (e) at least one ultrafiltration and/or at least one diafiltration of the product stream of steps (b), (c) and/or (d), characterized in that the at least two chromatography steps from (c) comprise a purification via at least two chromatography columns and/or membrane adsorbers in each case and that the process is carried out in a closed and modular manner The invention further provides a corresponding modular system for carrying out said method.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: June 30, 2020
    Assignee: BAYER AKTIENGESELLSCHAFT
    Inventors: Benjamin Maiser, Peter Schwan, Martin Lobedann, Volker Möhrle
  • VALIDATION OF CONTINUOUS VIRAL CLEARANCE
    Publication number: 20190316213
    Abstract: Disclosed herein is a method for validation of continuous viral clearance comprising the steps of providing a probe to be validated, spiking the probe in a valid manner, performing viral clearance, sampling the spiked probe and analyzing the sample of the spiked probe of step d).
    Type: Application
    Filed: October 20, 2017
    Publication date: October 17, 2019
    Inventors: Benjamin MAISER, Peter SCHWAN, Laura DAVID, Martin LOBEDANN
  • MODULAR SYSTEM AND PROCESS FOR THE CONTINUOUS, MICROBE-REDUCED PRODUCTION AND/OR PROCESSING OF A PRODUCT
    Publication number: 20180135006
    Abstract: The invention provides a method for the continuous, microbe-reduced production and/or processing of a biopharmaceutical, biological macromolecular product from a heterogeneous cell culture-fluid mixture, comprising the steps of: (a) providing a particle-free fluid from a heterogeneous cell culture-fluid mixture containing the product, in the form of a product stream, (b) at least one filtration, providing a filtrate, (c) at least two chromatography steps for purifying the product, (d) at least one virus depletion, (e) at least one ultrafiltration and/or at least one diafiltration of the product stream of steps (b), (c) and/or (d), characterized in that the at least two chromatography steps from (c) comprise a purification via at least two chromatography columns and/or membrane adsorbers in each case and that the process is carried out in a closed and modular manner The invention further provides a corresponding modular system for carrying out said method.
    Type: Application
    Filed: April 29, 2016
    Publication date: May 17, 2018
    Inventors: Benjamin MAISER, Peter SCHWAN, Martin LOBEDANN, Volker MÖHRLE