Patents by Inventor Benjamin Mann

Benjamin Mann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10678868
    Abstract: An exemplary method may comprise receiving a matrix for a set of documents, each cell of the matrix including a frequency value indicating a number of instances of a corresponding text segment in a corresponding document, receiving an indication of a relationship between two text segments, each of the two text segments associated with a first column and a second column, respectively, of the matrix, adjusting, for each document, a frequency value of the second column based on the frequency value of the first column, projecting each frequency value into a reference space to generate a set of projection values, identifying a plurality of subsets of the reference space, clustering, for each subset of the plurality of subsets, at least some documents that correspond to projection values, and generating a graph of nodes, each of the nodes identifying one or more of the documents corresponding to each cluster.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: June 9, 2020
    Assignee: Ayasdi AI LLC
    Inventors: Gunnar Carlsson, Anthony Bak, Jennifer Kloke, Benjamin Mann, Harlan Sexton
  • Publication number: 20190005036
    Abstract: An exemplary method may comprise receiving a matrix for a set of documents, each cell of the matrix including a frequency value indicating a number of instances of a corresponding text segment in a corresponding document, receiving an indication of a relationship between two text segments, each of the two text segments associated with a first column and a second column, respectively, of the matrix, adjusting, for each document, a frequency value of the second column based on the frequency value of the first column, projecting each frequency value into a reference space to generate a set of projection values, identifying a plurality of subsets of the reference space, clustering, for each subset of the plurality of subsets, at least some documents that correspond to projection values, and generating a graph of nodes, each of the nodes identifying one or more of the documents corresponding to each cluster.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Applicant: Ayasdi, Inc.
    Inventors: Gunnar Carlsson, Anthony Bak, Jennifer Kloke, Benjamin Mann, Harlan Sexton
  • Patent number: 10114823
    Abstract: An exemplary method may comprise receiving a matrix for a set of documents, each cell of the matrix including a frequency value indicating a number of instances of a corresponding text segment in a corresponding document, receiving an indication of a relationship between two text segments, each of the two text segments associated with a first column and a second column, respectively, of the matrix, adjusting, for each document, a frequency value of the second column based on the frequency value of the first column, projecting each frequency value into a reference space to generate a set of projection values, identifying a plurality of subsets of the reference space, clustering, for each subset of the plurality of subsets, at least some documents that correspond to projection values, and generating a graph of nodes, each of the nodes identifying one or more of the documents corresponding to each cluster.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: October 30, 2018
    Assignee: Ayasdi, Inc.
    Inventors: Gunnar Carlsson, Anthony Bak, Jennifer Kloke, Benjamin Mann, Harlan Sexton
  • Publication number: 20150127650
    Abstract: An exemplary method may comprise receiving a matrix for a set of documents, each cell of the matrix including a frequency value indicating a number of instances of a corresponding text segment in a corresponding document, receiving an indication of a relationship between two text segments, each of the two text segments associated with a first column and a second column, respectively, of the matrix, adjusting, for each document, a frequency value of the second column based on the frequency value of the first column, projecting each frequency value into a reference space to generate a set of projection values, identifying a plurality of subsets of the reference space, clustering, for each subset of the plurality of subsets, at least some documents that correspond to projection values, and generating a graph of nodes, each of the nodes identifying one or more of the documents corresponding to each cluster.
    Type: Application
    Filed: November 4, 2014
    Publication date: May 7, 2015
    Inventors: Gunnar Carlsson, Anthony Bak, Jennifer Kloke, Benjamin Mann, Harlan Sexton
  • Patent number: 7718400
    Abstract: DNA sequences comprising nucleic acids encoding fusion proteins comprising an Fc portion of an antibody attached at the N-terminus of an OB protein moiety, vectors comprising such DNA sequences, host cells comprising such vectors or DNA sequences, and processes for preparing such fusion proteins, and pharmaceutical compositions comprising such fusion proteins, are described.
    Type: Grant
    Filed: March 16, 2007
    Date of Patent: May 18, 2010
    Assignee: Amylin Pharmaceuticals, Inc.
    Inventors: Mary Ann Pelleymounter, Christopher Francis Toombs, Michael Benjamin Mann
  • Patent number: 7524940
    Abstract: The present invention provides methods and compositions for treating excess weight by administering OB protein in a form for constant supply, at a dosage of less than or equal to about 1 mg protein/kg body weight/day. Compositions and methods used for production of recombinant murine and human OB protein are also provided. Compositions and methods for preparing recombinant murine methionyl OB protein and recombinant human methionyl OB protein, including DNA sequences, vectors, host cells, methods of fermentation, and methods of purification are provided herein.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: April 28, 2009
    Assignee: Amgen, Inc.
    Inventors: Mary Ann Pelleymounter, Randy Ira Hecht, Michael Benjamin Mann
  • Publication number: 20090082275
    Abstract: The present invention provides methods and compositions for, for example, effecting weight loss and treating excess weight by administering OB protein, or a derivative thereof, in a form for constant supply, for example, continuous administration, at a dosage of less than or equal to about 1 mg protein/kg body weight/day. Compositions and methods used for production of recombinant murine and human OB protein are also provided. Compositions and methods for preparing recombinant murine methionyl OB protein and recombinant human methionyl OB protein, including DNA sequences, vectors, host cells, methods of fermentation, and methods of purification are provided herein.
    Type: Application
    Filed: November 12, 2008
    Publication date: March 26, 2009
    Applicant: AMGEN, INC.
    Inventors: Mary Ann Pelleymounter, Randy Ira Hecht, Michael Benjamin Mann
  • Patent number: 7208577
    Abstract: The present invention provides methods of creating and using OB protein compositions with an antibody constant region or portion thereof fused to an OB protein. The fusion protein is created by attaching the polyamino acids to the OB protein moiety. The fusion proteins can then be used for various therapeutic uses.
    Type: Grant
    Filed: January 11, 2005
    Date of Patent: April 24, 2007
    Assignee: Amgen, Inc.
    Inventors: Mary Ann Pelleymounter, Christopher Francis Toombs, Michael Benjamin Mann
  • Publication number: 20030203837
    Abstract: The present invention teaches compositions and methods relating to leptin fusion proteins comprising an antibody constant regions optionally attached to the N-terminus of the OB proteins. The compositions of the present invention may be used for treating obesity, diabetes, increasing lean muscle mass or for control of body composition.
    Type: Application
    Filed: May 30, 2003
    Publication date: October 30, 2003
    Inventors: Mary Ann Pelleymounter, Christopher Francis Toombs, Michael Benjamin Mann
  • Publication number: 20030054997
    Abstract: The present invention provides methods and compositions for treating excess weight by administering OB protein in a form for constant supply, at a dosage of less than or equal to about 1 mg protein/kg body weight/day. Compositions and methods used for production of recombinant murine and human OB protein are also provided. Compositions and methods for preparing recombinant murine methionyl OB protein and recombinant human methionyl OB protein, including DNA sequences, vectors, host cells, methods of fermentation, and methods of purification are provided herein.
    Type: Application
    Filed: August 5, 2002
    Publication date: March 20, 2003
    Applicant: Amgen Inc.
    Inventors: Mary Ann Pelleymounter, Randy Ira Hecht, Michael Benjamin Mann
  • Publication number: 20030040467
    Abstract: The present invention stems from the observation that administration of OB protein to non-obese as well as obese animals results in an increase of lean tissue mass. Thus, OB protein has the capacity to act, in addition to acting as a weight reducing agent, as an agent affecting lean tissue mass. As such, numerous lean tissue-mass increasing therapies are contemplated, even for patients who would not necessarily benefit from weight reduction. Thus, one aspect of the present invention is the use of OB protein (or analogs or derivatives thereof) for increasing lean tissue mass.
    Type: Application
    Filed: June 15, 1998
    Publication date: February 27, 2003
    Inventors: MARY ANN PELLEYMOUNTER, CHRISTOPHER FRANCIS TOOMBS, MICHAEL BENJAMIN MANN
  • Publication number: 20020115601
    Abstract: The present invention provides methods of creating and using OB protein compositions with an antibody constant region or portion thereof fused to an OB protein. The fusion protein is created by attaching the polyamino acids to the OB protein moiety. The fusion proteins can then be used for various therapeutic uses.
    Type: Application
    Filed: May 16, 2001
    Publication date: August 22, 2002
    Inventors: Mary Ann Pelleymounter, Christopher Francis Toombs, Michael Benjamin Mann
  • Publication number: 20020009798
    Abstract: The present invention provides methods and compositions for treating excess weight by administering OB protein in a form for constant supply, at a dosage of less than or equal to about 1 mg protein/kg body weight/day. Compositions and methods used for production of recombinant murine and human OB protein are also provided. Compositions and methods for preparing recombinant murine methionyl OB protein and recombinant human methionyl OB protein, including DNA sequences, vectors, host cells, methods of fermentation, and methods of purification are provided herein.
    Type: Application
    Filed: August 2, 1999
    Publication date: January 24, 2002
    Inventors: MARY ANN PELLEYMOUNTER, RANDY IRA HECHT, MICHAEL BENJAMIN MANN
  • Patent number: 6056136
    Abstract: A closure for press-on application to, and rotational removal from, a container having a cylindrical neck which includes a plurality of vertically spaced helical threads formed in the outer surface thereof in generally parallel relationship to each other. A flexible cylindrical skirt, preferably composed of a polyolefin such as polypropylene, includes a plurality of radially inwardly projecting spaced lugs that are circumferentially disposed around the inner cylindrical skirt surface and axially spaced therefrom for engagement with the threads on the cylindrical neck of the container. The lugs are composed of a deformable plastic material and are sized so that when the closure is applied to the container, an interference fit is provided between at least some of the lugs and at least some of the threads.
    Type: Grant
    Filed: November 30, 1995
    Date of Patent: May 2, 2000
    Assignee: White Cap, Inc.
    Inventors: James Taber, Benjamin Mann, Mark Petersen