Abstract: Described herein are compositions and methods for treating a lung disorder associated with dysregulated VEGF signaling. The PR1P peptide (DRVQRQTTTVVA, SEQ ID NO: 1) and variants thereof are able to enhance VEGF signaling in the lungs and reduce lung cell apoptosis (e.g., induced by toxicity or injury), thus treating the disorder.

Abstract: A flake measurement system of an oilseed crush operation includes a sampling system to collect an oilseed flake from the oilseed crush operation and place the oilseed flake on a supporting surface, and an imaging system to determine a thickness of the oilseed flake, with the imaging system including an imaging device to capture an image of a surface of the oilseed flake, the imaging system to process the image to identify a local minima region of the surface of the oilseed flake, and the imaging system to determine the thickness of the oilseed flake based on displacement of the local minima region relative to the supporting surface.

Abstract: A circuit includes a current sensor circuit having inputs and an output. The current sensor inputs are adapted to be coupled to inductor terminals a power converter. The current sensor circuit includes a tunable time constant circuit coupled between the current sensor inputs and the current sensor output. A time constant control circuit is coupled to a tunable time constant circuit, and is configured to tune the time constant circuit responsive to the current sensor output and another signal representative of inductor current. An adjustable gain circuit has a first input coupled to the current sensor output. A direct current resistance (DCR) control circuit has an output coupled to a second input of the adjustable gain circuit, and the DCR control circuit is configured to provide a gain adjust signal at the output thereof responsive to an average current of the inductor and a current command signal for the power converter.

Abstract: The present invention relates to a photochemical process for the manufacturing of a C-terminal ?-amide, which are a class of compounds that represent up to half of all biologically relevant peptide hormones. The invention provides mild, broad in scope, economically efficient process, which is suitable for large scale manufacturing.

Abstract: Methods and systems are provided for predicting reward liability data of reward programs. A method includes accessing, by a server system, historical reward related data associated with one or more reward programs administered by a reward program provider of reward program providers. The historical reward related data includes past redeemed reward points for each reward program aggregated on a particular time basis. Method includes identifying first seasonality patterns and second seasonality patterns associated with the historical reward related data. Method includes training a reward liability prediction model based on first and second seasonality patterns, wherein the trained time-series prediction model is configured to predict future reward liability data associated with the one or more reward programs.

Abstract: The system obtains an indication of a configuration update to perform on a component of a network and an indication of the component associated with the network. The configuration update is performed in multiple stages, including a pre-check stage, a configuration stage, and a verification stage. In the pre-check stage, the system obtains a parameter and an expected value of the parameter associated with the component. The system determines whether the component satisfies the expected value of the parameter by obtaining a value of the parameter associated with the component and comparing the obtained value to the expected value. Upon determining that the component satisfies the expected value of the parameter, the system performs the configuration stage. Upon performing the configuration update, the system performs the verification stage by testing whether the component is functioning. Upon determining that the component is functioning, the system provides the configuration update to UEs.

Abstract: A circuit includes a current sensor circuit having inputs and an output. The current sensor inputs are adapted to be coupled to inductor terminals a power converter. The current sensor circuit includes a tunable time constant circuit coupled between the current sensor inputs and the current sensor output. A time constant control circuit is coupled to a tunable time constant circuit, and is configured to tune the time constant circuit responsive to the current sensor output and another signal representative of inductor current. An adjustable gain circuit has a first input coupled to the current sensor output. A direct current resistance (DCR) control circuit has an output coupled to a second input of the adjustable gain circuit, and the DCR control circuit is configured to provide a gain adjust signal at the output thereof responsive to an average current of the inductor and a current command signal for the power converter.

Abstract: The invention provides an engineered carboxylic acid reductase (CAR) enzyme, a nucleic acid encoding the CAR enzyme, and a non-naturally occurring microbial organism comprising an exogenous nucleic acid encoding the CAR, an engineered transaminase (TA) enzyme, and/or a hexamethylenediamine (HMD) transaminase (TA2) enzyme. The invention provides a non-naturally occurring microbial organism that has a 1,6-hexanediol (HDO) pathway with a HDO pathway enzyme expressed in sufficient amounts to produce 6 aminocaproate semialdehyde, HDO, or both. The invention further provides a non-naturally occurring microbial organism that has an HMD pathway with a HMD pathway enzyme expressed in sufficient amounts to produce 6-aminocaproate semialdehyde, HMD, or both. The invention additionally provides bioderived HMD, 6-aminocaproate semialdehyde, and/or HDO and methods for producing bioderived HMD, 6-aminocaproate semialdehyde, and/or HDO.

Abstract: Techniques for selecting TV user interface (UI) transition characteristics are described. In accordance with various embodiments, a transition characteristics selection method is performed at a device (e.g., a cloud UI engine on a server) with one or more processors and a non-transitory memory. The UI engine receives a request for transitioning from a first screen to a second screen on a client device while in a real-time content presentation mode. In response to receiving the request and while in the real-time content presentation mode, the UI engine obtains one or more presentation conditions of the client device and selects one or more transition characteristics for transitioning from the first screen to the second screen based on costs associated with the one or more transition characteristics and the one or more presentation conditions.

Abstract: A circuit includes a current sensor circuit having inputs and an output. The current sensor inputs are adapted to be coupled to inductor terminals a power converter. The current sensor circuit includes a tunable time constant circuit coupled between the current sensor inputs and the current sensor output. A time constant control circuit is coupled to a tunable time constant circuit, and is configured to tune the time constant circuit responsive to the current sensor output and another signal representative of inductor current. An adjustable gain circuit has a first input coupled to the current sensor output. A direct current resistance (DCR) control circuit has an output coupled to a second input of the adjustable gain circuit, and the DCR control circuit is configured to provide a gain adjust signal at the output thereof responsive to an average current of the inductor and a current command signal for the power converter.

Abstract: In some implementations, a device includes one or more processors and a non-transitory memory. In some implementations, a method includes obtaining a request for a sequence of video frames that corresponds to a user interface operation being performed at a client device. In some implementations, the sequence of video frames is to be presented at the client device at a first frame rate. In some implementations, the method includes determining an availability of computing resources associated with providing the sequence of video frames to the client device. In some implementations, the method includes generating, based on the availability of computing resources, the sequence of video frames at a second frame rate that is greater than the first frame rate. In some implementations, the method includes triggering the client device to present the sequence of video frames at the first frame rate.

Abstract: Techniques for selecting TV user interface (UI) transition characteristics are described. In accordance with various embodiments, a transition characteristics selection method is performed at a device (e.g., a cloud UI engine on a server) with one or more processors and a non-transitory memory. The UI engine receives a request for transitioning from a first screen to a second screen on a client device while in a real-time content presentation mode. In response to receiving the request and while in the real-time content presentation mode, the UI engine obtains one or more presentation conditions of the client device and selects one or more transition characteristics for transitioning from the first screen to the second screen based on costs associated with the one or more transition characteristics and the one or more presentation conditions.

Abstract: A system includes a sensor configured to generate thoracic impedance data associated with a patient for a period of time, a memory storing machine-readable instructions, and a control system communicatively coupled to the sensor. The control system is arranged to provide control signals to one or more electronic devices and including one or more processors configured to execute the machine-readable instructions to analyze the generated thoracic impedance data associated with the patient; determine, based at least in part on the analysis, respiratory function signals and cardiac function signals, and whether the respiratory function signals and cardiac function signals satisfies a predetermined threshold, and cause an operation of the one or more electronic devices to be modified in response to determining the respiratory function signals and cardiac function signals satisfies the predetermined threshold.

Abstract: Methods, systems, and devices for electric machine drive calibration, verification, and efficiency improvement are disclosed herein. One electric machine controller for calibration includes a processor and memory and instructions that are stored in the memory and executable by the processor to identify a vehicle and/or electric machine frequency response during operation of the vehicle and use the electronic machine and a dynamic motor drive converter to provide source excitations based on the identified frequency response.

Abstract: The invention provides an engineered carboxylic acid reductase (CAR) enzyme, a nucleic acid encoding the CAR enzyme, and a non-naturally occurring microbial organism comprising an exogenous nucleic acid encoding the CAR, an engineered transaminase (TA) enzyme, and/or a hexamethylenediamine (HMD) transaminase (TA2) enzyme. The invention provides a non-naturally occurring microbial organism that has a 1,6-hexanediol (HDO) pathway with a HDO pathway enzyme expressed in sufficient amounts to produce 6 aminocaproate semi aldehyde, HDO, or both. The invention further provides a non-naturally occurring microbial organism that has an HMD pathway with a HMD pathway enzyme expressed in sufficient amounts to produce 6-aminocaproate semialdehyde, HMD, or both. The invention additionally provides bioderived HMD, 6-aminocaproate semialdehyde, and/or HDO and methods for producing bioderived HMD, 6-aminocaproate semialdehyde, and/or HDO.

Abstract: A light detection device for alerting an external monitoring system is disclosed herein. In an example, a photosensor apparatus is configured to use one or more photosensors to detect when light is emitted from an indicator lamp of a laboratory instrument. An output from the photosensor(s) is configured to cause a change in a relay switch, which sends a signal to a processor of a system monitor, which may be communicatively coupled to a network. After receiving a signal, the processor is configured to cause the system monitor to generate an alert or alarm indicative that at least one platelet sample within the laboratory instrument has tested positive for bacteria. The system monitor may display the alert or alarm via a user interface and/or may transmit one or more messages to client devices indicative of the light illumination.

Abstract: Yeast cells are genetically modified to disrupt a native metabolic pathway from dihydroxyacetone to glycerol. In certain aspects, the yeast cell is of the genera Kluyveromyces, Candida or Issatchenkia. In other aspects, the yeast cell is capable of producing at least one organic acid, such as lactate. The yeast cells produce significantly less glycerol than the wild-type strains, and usually produce greater yields of desired fermentation products. Yeast cells of the invention often grow well when cultivated, despite their curtailed glycerol production.

Abstract: The system obtains an indication of a configuration update to perform on a component of a network and an indication of the component associated with the network. The configuration update is performed in multiple stages, including a pre-check stage, a configuration stage, and a verification stage. In the pre-check stage, the system obtains a parameter and an expected value of the parameter associated with the component. The system determines whether the component satisfies the expected value of the parameter by obtaining a value of the parameter associated with the component and comparing the obtained value to the expected value. Upon determining that the component satisfies the expected value of the parameter, the system performs the configuration stage. Upon performing the configuration update, the system performs the verification stage by testing whether the component is functioning. Upon determining that the component is functioning, the system provides the configuration update to UEs.

Abstract: The disclosed system obtains an indication of a configuration update to perform on a component of a network and an indication of the component associated with the network. The configuration update is performed in multiple stages, including a pre-check stage, a configuration stage, and a verification stage. In the pre-check stage, the system obtains a parameter and an expected value of the parameter associated with the component. The system determines whether the component satisfies the expected value of the parameter by obtaining a value of the parameter associated with the component and comparing the obtained value to the expected value. Upon determining that the component satisfies the expected value of the parameter, the system performs the configuration stage. Upon performing the configuration update, the system performs the verification stage by testing whether the component is functioning. Upon determining that the component is functioning, the system provides the configuration update to UEs.

Abstract: A method for facilitating transactions by tenants in a multi-tenant architecture system is discussed. The method includes generating, with a multi-tenant computer system, a first representation of an entity in a first hierarchical data structure associated with an entity interface tenant of the multi-tenant computer system. The method includes receiving, with the multi-tenant computer system, a set of entity-specific policies useable to generate requests to individual ones of a plurality of transaction processing computer systems. The method includes generating, with the multi-tenant computer system, a second representation of the entity in a second hierarchical data structure associated with a particular transaction processing service tenant of a plurality of transaction processing service tenants of the multi-tenant computer system.