Patents by Inventor Benjamin Metcalf

Benjamin Metcalf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10871612
    Abstract: A universal interferometer (100) for coupling modes of electromagnetic radiation according to a transformation has N inputs and N outputs for inputting and outputting N modes of electromagnetic radiation into and from the interferometer. Waveguides (101, 102, 103, 104, 105) pass through the interferometer to connect the N inputs to the N outputs and to carry the N modes of electromagnetic radiation. The waveguides provide crossing points between pairs of waveguides and a reconfigurable beam splitter (107) implements a reconfigurable reflectivity and a reconfigurable phase shift at each crossing point. The waveguides and crossing points are arranged such that each of the N modes of electromagnetic radiation is capable of coupling with each of the other modes of electromagnetic radiation at respective reconfigurable beam splitters.
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: December 22, 2020
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: William Clements, Peter Humphreys, Benjamin Metcalf, Steven Kolthammer, Ian Walmsley
  • Publication number: 20200278494
    Abstract: A universal interferometer (100) for coupling modes of electromagnetic radiation according to a transformation has N inputs and N outputs for inputting and outputting N modes of electromagnetic radiation into and from the interferometer. Waveguides (101, 102, 103, 104, 105) pass through the interferometer to connect the N inputs to the N outputs and to carry the N modes of electromagnetic radiation. The waveguides provide crossing points between pairs of waveguides and a reconfigurable beam splitter (107) implements a reconfigurable reflectivity and a reconfigurable phase shift at each crossing point. The waveguides and crossing points are arranged such that each of the N modes of electromagnetic radiation is capable of coupling with each of the other modes of electromagnetic radiation at respective reconfigurable beam splitters.
    Type: Application
    Filed: March 11, 2020
    Publication date: September 3, 2020
    Inventors: William Clements, Peter Humphreys, Benjamin Metcalf, Steven Kolthammer, Ian Walmsley
  • Patent number: 10641954
    Abstract: A universal interferometer (100) for coupling modes of electromagnetic radiation according to a transformation has N inputs and N outputs for inputting and outputting N modes of electromagnetic radiation into and from the interferometer. Waveguides (101, 102, 103, 104, 105) pass through the interferometer to connect the N inputs to the N outputs and to carry the N modes of electromagnetic radiation. The waveguides provide crossing points between pairs of waveguides and a reconfigurable beam splitter (107) implements a reconfigurable reflectivity and a reconfigurable phase shift at each crossing point. The waveguides and crossing points are arranged such that each of the N modes of electromagnetic radiation is capable of coupling with each of the other modes of electromagnetic radiation at respective reconfigurable beam splitters.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: May 5, 2020
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: William Clements, Peter Humphreys, Benjamin Metcalf, Steven Kolthammer, Ian Walmsley
  • Publication number: 20190086610
    Abstract: A universal interferometer (100) for coupling modes of electromagnetic radiation according to a transformation has N inputs and N outputs for inputting and outputting N modes of electromagnetic radiation into and from the interferometer. Waveguides (101, 102, 103, 104, 105) pass through the interferometer to connect the N inputs to the N outputs and to carry the N modes of electromagnetic radiation. The waveguides provide crossing points between pairs of waveguides and a reconfigurable beam splitter (107) implements a reconfigurable reflectivity and a reconfigurable phase shift at each crossing point. The waveguides and crossing points are arranged such that each of the N modes of electromagnetic radiation is capable of coupling with each of the other modes of electromagnetic radiation at respective reconfigurable beam splitters.
    Type: Application
    Filed: February 24, 2017
    Publication date: March 21, 2019
    Inventors: William Clements, Peter Humphreys, Benjamin Metcalf, Steven Kolthammer, Ian Walmsley
  • Publication number: 20070253964
    Abstract: The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from neisserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
    Type: Application
    Filed: April 16, 2004
    Publication date: November 1, 2007
    Inventors: Gary Zlotnick, Leah Fletcher, John Farley, Liesel Bernfield, Robert Zagursky, Benjamin Metcalf
  • Publication number: 20070082007
    Abstract: The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
    Type: Application
    Filed: December 14, 2006
    Publication date: April 12, 2007
    Inventors: Gary Zlotnick, Leah Fletcher, John Farley, Liesel Bernfield, Robert Zagursky, Benjamin Metcalf
  • Publication number: 20070082006
    Abstract: The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
    Type: Application
    Filed: December 14, 2006
    Publication date: April 12, 2007
    Inventors: Gary Zlotnick, Leah Fletcher, John Farley, Liesel Bernfield, Robert Zagursky, Benjamin Metcalf
  • Publication number: 20070082866
    Abstract: The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
    Type: Application
    Filed: December 14, 2006
    Publication date: April 12, 2007
    Inventors: Gary Zlotnick, Leah Fletcher, John Farley, Liesel Bernfield, Robert Zagursky, Benjamin Metcalf
  • Publication number: 20070053927
    Abstract: The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia pneumoniae, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication process or in virulence, polypeptides encoded by such sequences, as well as vectors including the said sequences and cells or animals transformed with these vectors. The invention also relates to transcriptional gene products of the Chlamydia pneumoniae genome, such as, for example, antisense and ribozyme molecules, which can be used to control growth of the microorganism. The invention also relates to methods of detecting these nucleic acids or polypeptides and kits for diagnosing Chlamydia pneumoniae infection. The invention also relates to a method of selecting compounds capable of modulating bacterial infection and a method for the biosynthesis or biodegradation of molecules of interest using the said nucleotide sequences or the said polypeptides.
    Type: Application
    Filed: March 2, 2006
    Publication date: March 8, 2007
    Applicant: Serono Genetics Institute S.A.
    Inventors: Remy Griffais, Susan Hoiseth, Robert Zagursky, Benjamin Metcalf, Joel Peek, Banumathi Sankaran, Leah Fletcher
  • Publication number: 20060257413
    Abstract: The present invention relates to Neisseria ORF2086 proteins, crossreactive immunogenic proteins which can be isolated from nesserial strains or prepared recombinantly, including immunogenic portions thereof, biological equivalents thereof, antibodies that immunospecifically bind to the foregoing and nucleic acid sequences encoding each of the foregoing, as well as the use of same in immunogenic compositions that are effective against infection by Neisseria meningitidis serogroup B.
    Type: Application
    Filed: October 11, 2002
    Publication date: November 16, 2006
    Inventors: Gary Zlotnick, Leah Fletcher, John Farley, Liesel Bernfield, Robert Zagursky, Benjamin Metcalf
  • Publication number: 20060234260
    Abstract: The subject of the invention is the genomic sequence and the nucleotide sequences encoding polypeptides of Chlamydia trachomatis, such as cellular envelope polypeptides, which are secreted or specific, or which are involved in metabolism, in the replication process or in virulence, polypeptides encoded by such sequences, as well as vectors including the said sequences and cells or animals transformed with these vectors. The invention also relates to transcriptional gene products of the Chlamydia trachomatis genome, such as, for example, antisense and ribozyme molecules, which can be used to control growth of the microorganism. The invention also relates to methods of detecting these nucleic acids or polypeptides and kits for diagnosing Chlamydia trachomatis infection. The invention also relates to a method of selecting compounds capable of modulating bacterial infection and a method for the biosynthesis or biodegradation of molecules of interest using the said nucleotide sequences or the said polypeptides.
    Type: Application
    Filed: March 2, 2006
    Publication date: October 19, 2006
    Applicant: Serono Genetics Institute S.A.
    Inventors: Remy Griffais, Susan Hoiseth, Robert Zagursky, Benjamin Metcalf, Joel Peek, Banumathi Sankaran, Leah Fletcher