Patents by Inventor Benjamin Michael Shykind

Benjamin Michael Shykind has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC NUCLEIC ACIDS INCLUDING ASTROCYTE-DIRECTED PROMOTER CONSTRUCTS AND METHODS OF USING THE SAME
    Publication number: 20240156988
    Abstract: Synthetic nucleic acids are described that can be used for astrocyte-directed expression of heterologous nucleotide sequences. Also described are methods of using the same for astrocyte-directed expression of such nucleotide sequences for the treatment of neurodegenerative diseases.
    Type: Application
    Filed: November 10, 2023
    Publication date: May 16, 2024
    Inventors: Edmund Ching Schwartz, Benjamin Michael Shykind
  • GENE THERAPY FOR TREM2-ASSOCIATED DISEASES AND DISORDERS
    Publication number: 20240131192
    Abstract: Nucleic acids are described that encode for triggering receptor expressed on myeloid cells 2 (TREM2) and that can be used in expression constructs, vectors and gene therapies. Also described are methods of using the same for the treatment of TREM2-associated diseases and disorders, especially neurological diseases such as Alzheimer's Disease (AD), Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia (ALSP) or Nasu-Hakola Disease (NHD).
    Type: Application
    Filed: October 2, 2023
    Publication date: April 25, 2024
    Inventors: Sitharthan Kamalakaran, Priyam Raut, Anindya Kumar Sen, Benjamin Michael Shykind, Jessica Ruth Willen, Neda Masoudi