Patents by Inventor Benjamin Minkoff

Benjamin Minkoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250380729
    Abstract: A composition of matter including dried whole eggs and/or lyophilized whole eggs dissolved in a solvent comprising formic acid, nitric acid, or a combination of formic and nitric acid, and a method of making the same.
    Type: Application
    Filed: June 23, 2023
    Publication date: December 18, 2025
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Michael Sussman, Jamison Wolfer, Heather Burch, Benjamin Minkoff
  • Publication number: 20250353876
    Abstract: A method of attaching an azide moiety to a biomolecule. The method comprises contacting a biomolecule in a solution with an azide and a copper, for a time wherein at least one azide moiety is covalently bonded to the biomolecule to yield an azidylated biomolecule. The copper is copper (I), and can be generated from copper (II) by a reductant. The solution further comprises a copper ligand for reducing degradation of the biomolecule. The azilylated biomolecule can be attached to a reagent comprising an alkyne via a copper-catalyzed azide-alkyne cycloaddition (“CuAAC”) reaction or a strain-promoted alkyne-azide cycloaddition (“SPAAC”) reaction.
    Type: Application
    Filed: May 13, 2025
    Publication date: November 20, 2025
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Michael Sussman, Benjamin Minkoff, Jamison Wolfer, Yun Hu, Jennifer Schomaker
  • Publication number: 20250059228
    Abstract: A method of attaching an azide moiety to a biomolecule. The method entails contacting a biomolecule in a solution with an azide and an oxidizing agent, for a time and at a temperature wherein at least one azide moiety is covalently bonded to the biomolecule to yield an azidylated biomolecule. The method can be used to identify hydrophobic microenvironments in soluble proteins. Also, a method of attaching a reagent comprising an alkyne to a biomolecule. The method comprises reacting a biomolecule in a solution with an azide and a reagent comprising an alkyne, for a time and at a temperature wherein at least one reagent comprising an alkyne is covalently bonded to the biomolecule via triazole linkage.
    Type: Application
    Filed: December 22, 2022
    Publication date: February 20, 2025
    Applicant: Wisconsin Alumni Research Foundation
    Inventors: Michael Sussman, Benjamin Minkoff, Jamison Wolfer, Heather Burch