Patents by Inventor Benjamin N. Wang

Benjamin N. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High throughput separations based analysis systems
    Patent number: 7169277
    Abstract: Devices, systems and methods for use in separating sample materials into different fractions that employ bulk fluid flow for loading of samples followed by electrophoretic separation of the sample material. Devices employ configurations that optionally allow bulk sample loading with some or no displacement of a separation matrix within a separation conduit. Methods of using these devices, and systems that incorporate these devices are also envisioned.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: January 30, 2007
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Walter Ausserer, Luc J. Bousse, Robert S. Dubrow, Steven A. Sundberg, Andrea W. Chow, Benjamin N. Wang
  • Microfluidic viscometer
    Patent number: 7040144
    Abstract: Microfluidic devices, systems, and methods measure viscosity, flow times, and/or pressures, other flow characteristics within the channels, and the measured flow characteristics can be used to generate a desired flow. Multi-reservoir pressure modulator and pressure controller systems, electrokinetic systems and/or other fluid transport mechanisms can generate the flow, controllably mix fluids, and the like.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: May 9, 2006
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Michael Spaid, Andrea W. Chow, Benjamin N. Wang, Ring-Ling Chien, J. Wallace Parce, Anne R. Kopf-Sill, Josh Molho, Anubhav Tripathi, Matthew B. Kerby
  • Continuous flow methods for monitoring time dependent reactions
    Patent number: 7001716
    Abstract: Methods for monitoring time dependent reactions that comprise providing a flow channel, typically microscale in dimension, flowing at least two reagents into the flow channel and varying the flow rate of the mixture through the flow channel. By increasing and/or decreasing the flow rate of the reagent mixture from the point of mixing to the point of detection, one alters the amount of reaction time, allowing monitoring reaction kinetics over time.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: February 21, 2006
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Samuel D. H. Chan, Ring-Ling Chien, Andrea W. Chow, Benjamin N. Wang
  • Microfluidic viscometer
    Patent number: 6990851
    Abstract: Microfluidic devices, systems, and methods measure viscosity, flow times, and/or other flow characteristics within the channels, and the measured flow characteristics can be used to generate a desired flow. Multi-reservoir pressure modulator and pressure controller systems, electrokinetic systems and/or other fluid transport mechanisms can generate the flow, controllably mix fluids, and the like.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: January 31, 2006
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Michael Spaid, Andrea W. Chow, Benjamin N. Wang, Ring-Ling Chien, J. Wallace Parce, Anne R. Kopf-Sill
  • Microfluidic viscometer
    Publication number: 20040123649
    Abstract: Microfluidic devices, systems, and methods measure viscosity, flow times, and/or other flow characteristics within the channels, and the measured flow characteristics can be used to generate a desired flow. Multi-reservoir pressure modulator and pressure controller systems, electrokinetic systems and/or other fluid transport mechanisms can generate the flow, controllably mix fluids, and the like.
    Type: Application
    Filed: December 5, 2003
    Publication date: July 1, 2004
    Applicant: Caliper Technologies Corp.
    Inventors: Michael Spaid, Andrea W. Chow, Benjamin N. Wang, Ring-Ling Chien, J. Wallace Parce, Anne R. Kopf-Sill
  • Microfluidic methods, devices and systems for in situ material concentration
    Patent number: 6695009
    Abstract: Methods of concentrating materials within microfluidic channel networks by moving materials into regions in which overall velocities of the material are reduced, resulting in stacking of the material within those reduced velocity regions. These methods, devices and systems employ static fluid interfaces to generate the differential velocities, as well as counter-current flow methods, to concentrate materials within microscale channels.
    Type: Grant
    Filed: October 30, 2001
    Date of Patent: February 24, 2004
    Assignee: Caliper Technologies Corp.
    Inventors: Ring-Ling Chien, Benjamin N. Wang
  • Microfluidic viscometer
    Patent number: 6681616
    Abstract: Microfluidic devices, systems, and methods measure viscosity, flow times, and/or other flow characteristics within the channels, and the measured flow characteristics can be used to generate a desired flow. Multi-reservoir pressure modulator and pressure controller systems, electrokinetic systems and/or other fluid transport mechanisms can generate the flow, controllably mix fluids, and the like.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: January 27, 2004
    Assignee: Caliper Technologies Corp.
    Inventors: Michael Spaid, Andrea W. Chow, Benjamin N. Wang, Ring-Ling Chien, J. Wallace Parce, Anne R. Kopf-Sill
  • Methods, devices, and systems for monitoring time dependent reactions
    Publication number: 20030203353
    Abstract: Methods for monitoring time dependent reactions that comprise providing a flow channel, typically microscale in dimension, flowing at least two reagents into the flow channel and varying the flow rate of the mixture through the flow channel. By increasing and/or decreasing the flow rate of the reagent mixture from the point of mixing to the point of detection, one alters the amount of reaction time, allowing monitoring reaction kinetics over time.
    Type: Application
    Filed: May 20, 2003
    Publication date: October 30, 2003
    Applicant: Caliper Technologies Corp.
    Inventors: Samuel D.H. Chan, Ring-Ling Chien, Andrea W. Chow, Benjamin N. Wang
  • Microfluidic viscometer
    Publication number: 20030182991
    Abstract: Microfluidic devices, systems, and methods measure viscosity, flow times, and/or other flow characteristics within the channels, and the measured flow characteristics can be used to generate a desired flow. Multi-reservoir pressure modulator and pressure controller systems, electrokinetic systems and/or other fluid transport mechanisms can generate the flow, controllably mix fluids, and the like.
    Type: Application
    Filed: October 9, 2001
    Publication date: October 2, 2003
    Applicant: Caliper Technologies Corp.
    Inventors: Michael A. Spaid, Andrea W. Chow, Benjamin N. Wang, Ring-Ling Chien, J. Wallace Parce, Anne R. Kopf-Sill
  • Focusing of microparticles in microfluidic systems
    Patent number: 6592821
    Abstract: Methods and systems for particle focusing to increase assay throughput and sensitivity in microscale systems are provided. The invention includes methods for providing substantially uniform flow velocity to flowing particles in microfluidic devices. Methods of sorting members of particle populations, such as cells and various subcellular components are also provided. Integrated systems in which particles are focused and/or sorted are additionally included.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: July 15, 2003
    Assignee: Caliper Technologies Corp.
    Inventors: H. Garrett Wada, Anne R. Kopf-Sill, Marja Liisa Alajoki, J. Wallace Parce, Benjamin N. Wang, Andrea W. Chow, Robert S. Dubrow, Yevgeny Yurkovetsky, Javier Anibal Farinas
  • Methods, devices, and systems for monitoring time dependent reactions
    Patent number: 6589729
    Abstract: Methods for monitoring time dependent reactions that comprise providing a flow channel, typically microscale in dimension, flowing at least two reagents into the flow channel and varying the flow rate of the mixture through the flow channel. By increasing and/or decreasing the flow rate of the reagent mixture from the point of mixing to the point of detection, one alters the amount of reaction time, allowing monitoring reaction kinetics over time.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: July 8, 2003
    Assignee: Caliper Technologies Corp.
    Inventors: Samuel D. H. Chan, Ring-Ling Chien, Andrea W. Chow, Benjamin N. Wang
  • Microfluidic methods, devices and systems for in situ material concentration
    Publication number: 20030057092
    Abstract: Methods of concentrating materials within microfluidic channel networks by moving materials into regions in which overall velocities of the material are reduced, resulting in stacking of the material within those reduced velocity regions. These methods, devices and systems employ static fluid interfaces to generate the differential velocities, as well as counter-current flow methods, to concentrate materials within microscale channels.
    Type: Application
    Filed: July 26, 2002
    Publication date: March 27, 2003
    Applicant: Caliper Technologies Corp.
    Inventors: Ring-Ling Chien, Benjamin N. Wang, Persefoni Kechagia
  • Microfluidic viscometer
    Publication number: 20030041652
    Abstract: Microfluidic devices, systems, and methods measure viscosity, flow times, and/or pressures. other flow characteristics within the channels, and the measured flow characteristics can be used to generate a desired flow. Multi-reservoir pressure modulator and pressure controller systems, electrokinetic systems and/or other fluid transport mechanisms can generate the flow, controllably mix fluids, and the like.
    Type: Application
    Filed: July 26, 2002
    Publication date: March 6, 2003
    Applicant: Caliper Technologies Corp.
    Inventors: Michael Spaid, Andrea W. Chow, Benjamin N. Wang, Ring-Ling Chien, J. Wallace Parce, Anne R. Kopf-Sill, Josh Molho, Anubhav Tripathi, Matthew B. Kerby
  • Focusing of microparticles in microfluidic systems
    Patent number: 6506609
    Abstract: Methods and systems for particle focusing to increase assay throughput in microscale systems are provided. The invention includes methods for providing substantially uniform flow velocity to flowing particles in microfluidic devices. Methods of sorting members of particle populations, such as cells and various subcellular components are also provided. Integrated systems in which particles are focused and/or sorted are additionally included.
    Type: Grant
    Filed: May 11, 2000
    Date of Patent: January 14, 2003
    Assignee: Caliper Technologies Corp.
    Inventors: H. Garrett Wada, Anne R. Kopf-Sill, Marja Liisa Alajoki, J. Wallace Parce, Benjamin N. Wang, Andrea W. Chow, Robert S. Dubrow
  • Microfluidic methods, devices and systems for in situ material concentration
    Publication number: 20020079008
    Abstract: Methods of concentrating materials within microfluidic channel networks by moving materials into regions in which overall velocities of the material are reduced, resulting in stacking of the material within those reduced velocity regions. These methods, devices and systems employ static fluid interfaces to generate the differential velocities, as well as counter-current flow methods, to concentrate materials within microscale channels.
    Type: Application
    Filed: October 30, 2001
    Publication date: June 27, 2002
    Applicant: Caliper Technologies Corp.
    Inventors: Ring-Ling Chien, Benjamin N. Wang
  • High throughput separations based analysis systems
    Publication number: 20020033337
    Abstract: Devices, systems and methods for use in separating sample materials into different fractions that employ bulk fluid flow for loading of samples followed by electrophoretic separation of the sample material. Devices employ configurations that optionally allow bulk sample loading with some or no displacement of a separation matrix within a separation conduit. Methods of using these devices, and systems that incorporate these devices are also envisioned.
    Type: Application
    Filed: July 31, 2001
    Publication date: March 21, 2002
    Inventors: Walter Ausserer, Luc J. Bousse, Robert S. Dubrow, Steven A. Sundberg, Andrea W. Chow, Benjamin N. Wang
  • Methods, devices, and systems for monitoring time dependent reactions
    Publication number: 20010051338
    Abstract: Methods for monitoring time dependent reactions that comprise providing a flow channel, typically microscale in dimension, flowing at least two reagents into the flow channel and varying the flow rate of the mixture through the flow channel. By increasing and/or decreasing the flow rate of the reagent mixture from the point of mixing to the point of detection, one alters the amount of reaction time, allowing monitoring reaction kinetics over time.
    Type: Application
    Filed: January 31, 2001
    Publication date: December 13, 2001
    Inventors: Samuel D.H. Chan, Ring-Ling Chien, Andrea W. Chow, Benjamin N. Wang