Patents by Inventor Benjamin Pang-hsien Tu

Benjamin Pang-hsien Tu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIPARTITE MOLECULES AND USES THEREOF IN TREATING DISEASES ASSOCIATED WITH ABNORMAL PROTEIN AGGREGATES
    Publication number: 20210198332
    Abstract: Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.
    Type: Application
    Filed: November 27, 2020
    Publication date: July 1, 2021
    Inventors: Benjamin Pang-Hsien TU, Rita PY CHEN, Joseph Jen-Tse HUANG, Yijuang CHERN, Yu-Song JANG, Xiang-Me LAI, Tai-Yan LIAO, Te-Hsien KUNG
  • Bipartite molecules and uses thereof in treating diseases associated with abnormal protein aggregates
    Patent number: 10882890
    Abstract: Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.
    Type: Grant
    Filed: July 24, 2015
    Date of Patent: January 5, 2021
    Assignee: ACADEMIA SINICA
    Inventors: Benjamin Pang-Hsien Tu, Rita Py Chen, Joseph Jen-Tse Huang, Yijuang Chern, Yu-Song Jang, Xiang-Me Lai, Tai-Yan Liao, Te-Hsien Kung
  • Compounds for use in prevention and treatment of neurodegenerative diseases and pain
    Patent number: 10301348
    Abstract: Compounds for use in prevention and treatment of neurodegenerative disease and pain are disclosed. In one embodiment of the invention, the compound is selected from the group consisting of N6-[(3-halothien-2-yl)methyl]adenosine, N6-[(4-halothien-2-yl)methyl]adenosine, and N6-[(5-halothien-2-yl)methyl]adenosine. In another embodiment of the invention, the compound is selected from the group consisting of N6-[(2-bromothien-3-yl)methyl]adenosine, N6-[(4-bromothien-3-yl)methyl]adenosine, N6-[(5-bromothien-3-yl)methyl]adenosine N6-[(2-chlorothien-3-yl)methyl]adenosine, N6-[(4-chlorothien-3-yl)methyl]adenosine, and N6-[(5-chlorothien-3-yl)methyl]adenosine. Also disclosed are methods of making and using the same.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: May 28, 2019
    Assignee: ACADEMIA SINICA
    Inventors: Jim-Min Fang, Yun-Lian Lin, Jung-Hsin Lin, Chun-Jung Lin, Yijuang Chern, Nai-Kuei Huang, Hung-Li Wang, Benjamin Pang-hsien Tu, Chih-Cheng Chen
  • BIPARTITE MOLECULES AND USES THEREOF IN TREATING DISEASES ASSOCIATED WITH ABNORMAL PROTEIN AGGREGATES
    Publication number: 20180086801
    Abstract: Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.
    Type: Application
    Filed: July 24, 2015
    Publication date: March 29, 2018
    Applicant: Academia Sinica
    Inventors: Benjamin Pang-hsien Tu, Rita PY Chen, Joseph Jen-Tse Huang, Yijuang Chern, Yu-Song Jang, Xiang-Me Lai, Tai-Yan Liao, Te-Hsien Kung
  • BIPARTITE MOLECULES AND USES THEREOF IN TREATING DISEASES ASSOCIATED WITH ABNORMAL PROTEIN AGGREGATES
    Publication number: 20170226169
    Abstract: Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.
    Type: Application
    Filed: July 24, 2015
    Publication date: August 10, 2017
    Applicant: Academia Sinica
    Inventors: Benjamin Pang-hsien Tu, Rita PY Chen, Joseph Jen-Tse Huang, Yijuang Chern, Yu-Song Jang, Xiang-Me Lai, Tai-Yan Liao, Te-Hsien Kung
  • COMPOUNDS FOR USE IN PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES AND PAIN
    Publication number: 20160264613
    Abstract: Compounds for use in prevention and treatment of neurodegenerative disease and pain are disclosed. In one embodiment of the invention, the compound is selected from the group consisting of N6-[(3-halothien-2-yl)methyl]adenosine, N6-[(4-halothien-2-yl)methyl]adenosine, and N6-[(5-halothien-2-yl)methyl]adenosine. In another embodiment of the invention, the compound is selected from the group consisting of N6-[(2-bromothien-3-yl)methyl]adenosine, N6-[(4-bromothien-3-yl)methyl]adenosine, N6-[(5-bromothien-3-yl)methyl]adenosine N6-[(2-chlorothien-3-yl)methyl]adenosine, N6-[(4-chlorothien-3-yl)methyl]adenosine, and N6-[(5-chlorothien-3-yl)methyl]adenosine. Also disclosed are methods of making and using the same.
    Type: Application
    Filed: October 22, 2014
    Publication date: September 15, 2016
    Inventors: Jim-Min Fang, Yun-Lian LIn, Jung-Hsin Lin, Chun-Jung Lin, Yijuang Chem, Nai-Kuei Huang, Hung-Li Wang, Benjamin Pang-hsien Tu, Chih-Cheng Chen