Abstract: The present invention is related to compounds, methods, compositions and uses that are able to inhibit mitochondrial pyruvate carrier (MPC) activity and which are useful for immunotherapy, in particular T-cell therapies, immune check point inhibitors or anti-cancer vaccine.

Abstract: Systems and methods are provided for automatically assigning a task identified from information received from one or more sensors. The automatically assigning including identifying a plurality of matches between the task and more than one of the plurality of individuals based on attributes of the individuals and requirements of the task; and in response to identifying a match, automatically assigning the task to the individual corresponding to a match having a highest ranking, wherein the automatically assigning comprises displaying the task on the display within the mobile application associated with the individual. Additionally, the systems and methods may determine one or more additional tasks that are related to the task and automatically assigning the one or more additional tasks to one or more individuals.

Abstract: Computer-implemented systems and methods are provided for generating automated and real-time graphical user interfaces.

Abstract: Computer-implemented systems and methods are provided for automated task scheduling and management. In some embodiments, a system for automated task scheduling may comprise at least one processor configured to receive a request with information for a task to be performed by a respondent. The one or more processors may retrieve employee information and, based on one or more attributes in the employee information and one or more attributes in the task information, identify one or more employees to complete the task. The one or more processors may assign the task to the identified employee(s), and monitor a status of the task based on periodic inputs from the employee.

Abstract: A device and method for color correction of two camera systems each having an imaging device and an illumination source. The camera systems are separately white balanced with the imaging device outside a scene. Their white balance gains and color correction matrices are saved. Based on the measurements, combined white balance gains and combined color correction matrices are computed and saved. Thereafter, with the imaging devices in a scene, performing white balancing by measuring the R, G, and B values of both imaging devices together, and then white balancing by measuring the R, G, and B values of each separate imaging device with the other camera system's light off. Comparisons are made of each camera's scene measurements against the combined scene measurements. If they are significantly different, the combined light set of white balance gain and color correction matrix is applied to digital signal processing paths of each camera system.

Abstract: An active shooter response robot enabling real-time audio and video data collection and additional functionality for the application threat-elimination tactics, including negotiations, against an active shooter. The active shooter response robot is unmanned and non-autonomous as it is controlled remotely by a human operator. The active shooter response robot provides a bullet-proof compartment for storing offensive deterrence and equipment that can be brought to bear during an active shooting situation.

Abstract: A sideband communication system has been developed for a conveyor system. A controller card controls the operation of a conveyor zone and communicates information about each conveyor in the conveyor zone. The controller card is assigned to control and monitor the operation of one or more of these zones of conveyors. The cards of adjacent zones are daisy-chained together to facilitate communication with one another and with other systems like a programmable logic controller (PLC). In addition to the standard controller area network (CAN) communication protocol, the controller cards further communicate amongst themselves using a sideband communication protocol that is outside the realm of the standard CAN communication protocol. The sideband communication protocol allows the cards to communicate with each other without interfering with normal network communications which provides additional capabilities such as automatic card self-identification.

Abstract: A roller detection system has been developed in which a controller card is configured to automatically detect the type of motorized drive roller being used in the conveyor system. With this automatic detection capability, the controller card is able to automatically control the motorized drive roller without the need for manual reprogramming or reconfiguration. For instance, the controller card can detect whether the motorized drive roller is controlled through an analog or digital signal as well as the voltage required to control or power the motorized drive roller, and based on this roller type detection, the controller card is automatically configured to control the motorized drive roller. The system is further adapted to facilitate a sensor-less or photoeye-less zero pressure (ZP) conveyor system. The controller card is configured to support a secondary power source that allows the motorized drive roller settings during e-stop and other power loss conditions.

Abstract: A data analytics system has been developed for conveyor systems that helps to monitor items along conveyors as well as assist in monitoring the status or health of equipment of the conveyor. Tracking items in conveying systems within a facility can be difficult. Conveyed items can become jammed, lost, or even fall off the conveyor. Based on input from motors and sensors along the conveyor, the data analytics system is able to detect lost or jammed items. With input from the sensors, the data analytics system is also configured to detect equipment wear and damage. The data analytic system further aggregates data from the various conveyor systems to generate statistics as well as other information that can be used for modeling and simulating the conveyor system. The aggregate data can be used to generate measures such as travel efficiency analytics for reporting purposes.

Abstract: This disclosure relates to instruments and methods of performing an endoscopy. An endoscope for producing images of a surgery in vivo may include a hub and an imaging rod extending from the hub, the imaging rod being configured to direct the light to an imaging sensor located adjacent to a distal end of the imaging rod, the hub and the imaging rod being attached to form an assembly having a center of mass established distally of the hub. In other implementations, the hub may be omitted.

Abstract: A device and method for color correction of two camera systems each having an imaging device and an illumination source. The camera systems are separately white balanced with the imaging device outside a scene. Their white balance gains and color correction matrices are saved. Based on the measurements, combined white balance gains and combined color correction matrices are computed and saved. Thereafter, with the imaging devices in a scene, performing white balancing by measuring the R, G, and B values of both imaging devices together, and then white balancing by measuring the R, G, and B values of each separate imaging device with the other camera system's light off. Comparisons are made of each camera's scene measurements against the combined scene measurements. If they are significantly different, the combined light set of white balance gain and color correction matrix is applied to digital signal processing paths of each camera system.

Abstract: This disclosure relates to instruments and methods of performing an endoscopy. An endoscope for producing images of a surgery in vivo may include a hub and an imaging rod extending from the hub, the imaging rod being configured to receive light and direct the light to an imaging sensor located adjacent to a distal end of the imaging rod, the hub and the imaging rod being attached to form an assembly having a center of mass established distally of the hub. In other implementations, the hub may be omitted.

Abstract: A device and method for color correction of two camera systems each having an imaging device and an illumination source. The camera systems are separately white balanced with the imaging device outside a scene. Their white balance gains and color correction matrices are saved. Based on the measurements, combined white balance gains and combined color correction matrices are computed and saved. Thereafter, with the imaging devices in a scene, performing white balancing by measuring the R, G, and B values of both imaging devices together, and then white balancing by measuring the R, G, and B values of each separate imaging device with the other camera system's light off. Comparisons are made of each camera's scene measurements against the combined scene measurements. If they are significantly different, the combined light set of white balance gain and color correction matrix is applied to digital signal processing paths of each camera system.

Abstract: This disclosure relates to instruments and methods of performing an endoscopy. An endoscope for producing images of a surgery in vivo may include a hub and an imaging rod extending from the hub, the imaging rod being configured to receive light and direct the light to an imaging sensor located adjacent to a distal end of the imaging rod, the hub and the imaging rod being attached to form an assembly having a center of mass established distally of the hub. In other implementations, the hub may be omitted.

Abstract: Disclosed herein are new compounds, pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).

Abstract: A device and method for color correction of two camera systems each having an imaging device and an illumination source. The camera systems are separately white balanced with the imaging device outside a scene. Their white balance gains and color correction matrices are saved. Based on the measurements, combined white balance gains and combined color correction matrices are computed and saved. Thereafter, with the imaging devices in a scene, performing white balancing by measuring the R, G, and B values of both imaging devices together, and then white balancing by measuring the R, G, and B values of each separate imaging device with the other camera system's light off. Comparisons are made of each camera's scene measurements against the combined scene measurements. If they are significantly different, the combined light set of white balance gain and color correction matrix is applied to digital signal processing paths of each camera system.

Abstract: A device and method for color correction of two camera systems each having an imaging device and an illumination source. The camera systems are separately white balanced with the imaging device outside a scene. Their white balance gains and color correction matrices are saved. Based on the measurements, combined white balance gains and combined color correction matrices are computed and saved. Thereafter, with the imaging devices in a scene, performing white balancing by measuring the R, G, and B values of both imaging devices together, and then white balancing by measuring the R, G, and B values of each separate imaging device with the other camera system's light off. Comparisons are made of each camera's scene measurements against the combined scene measurements. If they are significantly different, the combined light set of white balance gain and color correction matrix is applied to digital signal processing paths of each camera system.

Abstract: A sorter includes a slat and a shoe disposed along the slat. The shoe includes a base and a bumper. The base has an exterior surface. The bumper is coupled to the base. The shoe moves in a lateral direction along the slat to move an item across the slat. The bumper deflects when a threshold force is applied indicative of a jam to allow the item to slide over the base. A drive system is configured to move the slat in a longitudinal direction. The slat includes slat pins. A slat coupler couples the slat to the drive system. The slat coupler includes a carriage base, a coupler arm, and a retainer clip. The carriage base with pin notches is coupled to the drive system. The coupler arm with pin notches is pivotally coupled to the carriage base. The coupler arm is closed against the carriage base with the slat pins disposed within the pin notches. The retainer clip is clipped to the slat pins.