Abstract: The present invention relates to microvesicles derived from natural tumor cells and tumor cells produced in vitro under a stress stimulus, such as radiation, which can be used in an effective manner as a therapeutic vaccine for cancer. The invention also relates to a therapeutic vaccine formulation containing the microvesicles, processes for the preparation and medical use thereof as a therapeutic vaccine to stimulate the antitumor immune system and treat cancer.

Abstract: Varicella-zoster virus belongs to the herpesvirus family and its main host are humans, producing 2 different diseases: varicella in children and young adults and zoster in elder or immunodepressed subjects. We reported in the scientific medical literature the unexpected finding that the role of varicella-zoster virus in the pathogeny of Multiple Sclerosis (Archives of Neurology 61: 529-532). This finding allows us to foresee the use of a vaccine against this virus with preventive and therapeutic ends for multiple sclerosis which eventually could also be applicable in the prevention of varicella and zoster.

Abstract: Varicella-zoster virus belongs to the herpesvirus family and its main host are humans, producing 2 different diseases: varicella in children and young adults and zoster in elder or immunodepressed subjects. We reported in the scientific medical literature the unexpected finding that the role of varicella-zoster virus in the pathogeny of Multiple Sclerosis (Archives of Neurology 61: 529-532). This finding allows us to foresee the use of a vaccine against this virus with preventive and therapeutic ends for multiple sclerosis which eventually could also be applicable in the prevention of varicella and zoster.