Abstract: A valving arrangement is provided herein for regulating fluidics of modules usable in a combinatorial drug delivery device. The valving includes a slidable piston valve, adjustable to selectively seal an outlet path from a drug vial and a sealing port, in parallel to a vent, for selectively sealing an inlet path to the drug vial. Advantageously, the subject invention allows for applied negative pressure to adjust the valving to allow flow between serially-connected modules forming a drug delivery device.

Abstract: Embodiments of the systems described herein can implement one or more visitor tearing processes. Visitor tearing can include, among other things, one or more processes by which multiple visitors that may appear to be the same visitor may be separated into different visitor profiles due to the leveraging of one or more unique persistent identifiers.

Abstract: The present invention relates to compounds of Formula I that function as inhibitors of BCL6 (B-cell lymphoma 6) activity: wherein X1, X2, R1, R2 and R3 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which BCL6 activity is implicated.

Abstract: Biodegradable copolymers obtainable via radically initiated emulsion polymerization processes are provided. The biodegradable copolymers contain one or more monomer units of the formula I, and vinyl acetate units. In formula I, n=1 to 3, X1 and X2 independently of one another are the atoms O or S or the group N—R7, R1 and R2 independently of one another are hydrogen, an alkyl, alkenyl, alkoxy or aryl radical or a spirocyclic aliphatic group, and R3, R4, R5, R6 and R7 independently of one another are hydrogen or an alkyl or aryl radical.

Abstract: The present invention relates to compounds of Formula I that function as inhibitors of BCL6 (B-cell lymphoma 6) activity: wherein X1, X2, R1, R2 and R3 are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which BCL6 activity is implicated.

Abstract: A hair care accessory is provided for use in drying and/or styling hair. The hair care accessory can include an elongate frame having a longitudinal axis and an inner lumen extending there through along the longitudinal axis. The hair care accessory can also include a plurality of plates disposed on the elongate frame. The plurality of plates can include a first row of plates that can be spaced circumferentially around a first longitudinal portion of the elongate frame, and at least one second row of plates that can be spaced circumferentially around a second longitudinal portion of the elongate frame. Each plate in the first row of plates can define a first longitudinally extending outlet and each plate in the second row of plates can define a second longitudinally extending outlet. The second longitudinally extending outlet being circumferentially offset from the first longitudinally extending outlet.

Abstract: A hair care accessory is provided for use in drying and/or styling hair. The hair care accessory can include an elongate frame having a longitudinal axis and an inner lumen extending there through along the longitudinal axis. The hair care accessory can also include a plurality of plates disposed on the elongate frame. The plurality of plates can include a first row of plates that can be spaced circumferentially around a first longitudinal portion of the elongate frame, and at least one second row of plates that can be spaced circumferentially around a second longitudinal portion of the elongate frame. Each plate in the first row of plates can define a first longitudinally extending outlet and each plate in the second row of plates can define a second longitudinally extending outlet. The second longitudinally extending outlet being circumferentially offset from the first longitudinally extending outlet.

Abstract: A hair care accessory is provided for use in drying and/or styling hair. The hair care accessory can include an elongate frame having a longitudinal axis and an inner lumen extending there through along the longitudinal axis. The hair care accessory can also include a plurality of plates disposed on the elongate frame. The plurality of plates can include a first row of plates that can be spaced circumferentially around a first longitudinal portion of the elongate frame, and at least one second row of plates that can be spaced circumferentially around a second longitudinal portion of the elongate frame. Each plate in the first row of plates can define a first longitudinally extending outlet and each plate in the second row of plates can define a second longitudinally extending outlet. The second longitudinally extending outlet being circumferentially offset from the first longitudinally extending outlet.

Abstract: A hair care accessory is provided for use in drying and/or styling hair. The hair care accessory can include an elongate frame having a longitudinal axis and an inner lumen extending there through along the longitudinal axis. The hair care accessory can also include a plurality of plates disposed on the elongate frame. The plurality of plates can include a first row of plates that can be spaced circumferentially around a first longitudinal portion of the elongate frame, and at least one second row of plates that can be spaced circumferentially around a second longitudinal portion of the elongate frame. Each plate in the first row of plates can define a first longitudinally extending outlet and each plate in the second row of plates can define a second longitudinally extending outlet. The second longitudinally extending outlet being circumferentially offset from the first longitudinally extending outlet.

Abstract: Various exemplary attachments for hair care appliances and methods of using attachments for hair care appliances are provided. In general, a hair care appliance in an exemplary embodiment is in the form of a hair dryer that has an air inlet and at least one air outlet, and various internal components that facilitate use and operation of the hair care appliance, such as a fan, motor, and heater. In an exemplary embodiment, the hair care appliance is configured to releasably couple to an attachment so that the hair care appliance and the attachment are in electrical communication.

Abstract: A method of fabricating a multijunction solar cell array on a carrier using one or more automated processes, the method comprising providing a first multijunction solar cell including a first contact pad and a second contact pad disposed adjacent the top surface of the multijunction solar cell along a first peripheral edge thereof attaching a first electrical interconnect to the first contact pad of said first multijunction solar cell using a pick and place process attaching a second electrical interconnect to the second contact pad of the first multijunction solar cell using a pick and place process positioning in the first multijunction solar cell over an adhesive region of a permanent carrier using an automated machine/vision apparatus and bonding the first multijunction solar cell to the adhesive region using pressure and/or heat.

Abstract: The present invention relates to compounds that function as inhibitors of BCL6 (B-cell lymphoma 6) activity. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which BCL6 activity is implicated.

Abstract: Embodiments of the systems described herein can implement one or more visitor tearing processes. Visitor tearing can include, among other things, one or more processes by which multiple visitors that may appear to be the same visitor may be separated into different visitor profiles due to the leveraging of one or more unique persistent identifiers.

Abstract: A system and method for removing a backing from a ply of composite material is disclosed. The system includes a roller having a roller axis and a roller surface that circumscribes the roller axis. The system also includes an adhesion feature disposed on the roller surface. The system further includes a roller drive to move the roller along a travel path that is perpendicular to the roller axis and to rotate the roller about the roller axis.

Abstract: A system and method for removing a backing from a ply of composite material is disclosed. The system includes a roller having a roller axis and a roller surface that circumscribes the roller axis. The system also includes an adhesion feature disposed on the roller surface. The system further includes a roller drive to move the roller along a travel path that is perpendicular to the roller axis and to rotate the roller about the roller axis.

Abstract: An exemplary compounding method of controlling a compounding device to prepare an admixture of at least two distinct material sources can include examining material source solutions for incompatibility of the ingredients and operating a first and a second pump to prevent one of the incompatible source solutions from entering a common flow path. The processing method can detect degradation of a fluid line by evaluating one or more of calibration error rate data, cumulative volumetric flow data, or cumulative pump operation data. The processing method can also selectively transfer a first group of source solutions using the first pump, receiving pump data from one or more sensors that sense actions of the pumps, applying fluid correction factors and calculating discrete pump movements, the pump movements being indicative of an amount of source solution displacement by a pump, and operating the pumps to selectively dispense the source solution amounts according to a preparation order.

Abstract: Embodiments of the systems described herein can implement one or more visitor tearing processes. Visitor tearing can include, among other things, one or more processes by which multiple visitors that may appear to be the same visitor may be separated into different visitor profiles due to the leveraging of one or more unique persistent identifiers.

Abstract: A method of fabricating a multijunction solar cell panel by providing a plurality of multijunction solar cells; dispensing out uncured silicone coating on the solar cells using an automated process with visual recognition, and curing the silicone coating on the solar cell to complete the Cell-Interconnect-Cover Glass (CIC) assembly.