Patents by Inventor Benjamin Robert TAFT

Benjamin Robert TAFT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and compositions for the treatment of parasitic diseases
    Patent number: 11597733
    Abstract: The present invention provides a compound of formula (Ia) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, solid forms, combinations of pharmacologically active agents, pharmaceutical compositions and methods of using such compounds and solid forms thereof to treat or prevent parasitic diseases, for example malaria.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: March 7, 2023
    Assignee: Novartis AG
    Inventors: Nicole Alice Blaquiere, Richard Yichong Huang, Thomas Martin Kirrane, Jr., Andreas Kordikowski, Anne-Catherine Mata, Christopher Ronald Sarko, Benjamin Robert Taft, Grace Lamprecht Waldron, Fumiaki Yokokawa, Tingying Zhu
  • Tricyclic compounds useful to treat orthomyxovirus infections
    Patent number: 11453677
    Abstract: The present invention provides a compound of Formula (I) including pharmaceutically acceptable salts thereof: (I) and therapeutic uses of these compounds. The invention further provides pharmaceutical compositions comprising these compounds, compositions comprising these compounds with a therapeutic co-agent, and methods of using the compounds and compositions to treat viral infections.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: September 27, 2022
    Assignee: Novartis AG
    Inventors: Rama Jain, Dennis Christofer Koester, James R. Manning, James Clifford Sutton, Benjamin Robert Taft, Lifeng Wan, Qian Zhao
  • Fused tricyclic pyridazinone compounds useful to treat orthomyxovirus infections
    Patent number: 11098051
    Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: August 24, 2021
    Assignee: Novartis AG
    Inventors: Rama Jain, Dennis Christofer Koester, James R. Manning, Vanessa Marx, Daniel Poon, James Clifford Sutton, Benjamin Robert Taft, Lifeng Wan, Aregahegn Yifru, Qian Zhao
  • COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES
    Publication number: 20210115065
    Abstract: The present invention provides a compound of formula (Ia) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, solid forms, combinations of pharmacologically active agents, pharmaceutical compositions and methods of using such compounds and solid forms thereof to treat or prevent parasitic diseases, for example malaria.
    Type: Application
    Filed: October 21, 2020
    Publication date: April 22, 2021
    Inventors: Nicole Alice Blaquiere, Richard Yichong Huang, Thomas Martin Kirrane, JR., Andreas Kordikowski, Anne-Catherine Mata, Christopher Ronald Sarko, Benjamin Robert Taft, Grace Lamprecht Waldron, Fumiaki Yokokawa, Tingying Zhu
  • Tricyclic compounds useful to treat orthomyxovirus infections
    Patent number: 10858366
    Abstract: The present invention provides a compound of Formula (I) including pharmaceutically acceptable salts thereof: and therapeutic uses of these compounds. The invention further provides pharmaceutical compositions comprising these compounds, compositions comprising these compounds with a therapeutic co-agent, and methods of using the compounds and compositions to treat viral infections.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: December 8, 2020
    Assignee: Novartis AG
    Inventors: Rama Jain, Dennis Christofer Koester, James R. Manning, James Clifford Sutton, Benjamin Robert Taft, Lifeng Wan, Qian Zhao
  • Tricyclic Compounds Useful to Treat Orthomyxovirus Infections
    Publication number: 20200347072
    Abstract: The present invention provides a compound of Formula (I) including pharmaceutically acceptable salts thereof: (I) and therapeutic uses of these compounds. The invention further provides pharmaceutical compositions comprising these compounds, compositions comprising these compounds with a therapeutic co-agent, and methods of using the compounds and compositions to treat viral infections.
    Type: Application
    Filed: July 20, 2020
    Publication date: November 5, 2020
    Inventors: Rama JAIN, Dennis Christofer KOESTER, James R. MANNING, James Clifford SUTTON, Benjamin Robert TAFT, Lifeng WAN, Qian ZHAO
  • FUSED TRICYCLIC PYRIDAZINONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS
    Publication number: 20200123167
    Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.
    Type: Application
    Filed: August 25, 2017
    Publication date: April 23, 2020
    Inventors: Rama JAIN, Dennis Christofer KOESTER, James R. MANNING, Vanessa MARX, Daniel POON, James Clifford SUTTON, Benjamin Robert TAFT, Lifeng WAN, Aregahegn YIFRU, Qian ZHAO
  • TRICYCLIC COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS
    Publication number: 20190092780
    Abstract: The present invention provides a compound of Formula (I) including pharmaceutically acceptable salts thereof: and therapeutic uses of these compounds. The invention further provides pharmaceutical compositions comprising these compounds, compositions comprising these compounds with a therapeutic co-agent, and methods of using the compounds and compositions to treat viral infections.
    Type: Application
    Filed: March 7, 2017
    Publication date: March 28, 2019
    Inventors: Rama JAIN, Dennis Christofer KOESTER, James R. MANNING, James Clifford SUTTON, Benjamin Robert TAFT, Lifeng WAN, Qian ZHAO