Patents by Inventor Benjamin ROSCOE

Benjamin ROSCOE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETING BCL11A DISTAL REGULATORY ELEMENTS WITH A CAS9-CAS9 FUSION FOR FETAL HEMOGLOBIN REINDUCTION
    Publication number: 20210047632
    Abstract: Provided herein are methods and compositions for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level. Also provided herein are methods and compositions relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels.
    Type: Application
    Filed: July 20, 2018
    Publication date: February 18, 2021
    Applicants: THE CHILDREN'S MEDICAL CENTER CORPORATION, UNIVERSITY OF MASSACHUSETTS
    Inventors: Daniel E. BAUER, Scot WOLFE, Mehmet Fatih BOLUKBASI, Benjamin ROSCOE, Pengpeng LIU, Kevin LUK, Yuxuan WU, Jing ZENG