Patents by Inventor Benjamin Rubin

Benjamin Rubin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210290569
    Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.
    Type: Application
    Filed: June 2, 2021
    Publication date: September 23, 2021
    Applicants: MESHABERASE, LLC, United States Department of Health and Human Services, National Institutes of Health
    Inventors: Benjamin Rubin, Mark Gilbert, Jinkyu Jung
  • Publication number: 20210267529
    Abstract: Systems and methods are provided for a multi-modal sleep system comprising a data processor for operating in a plurality of operating modes. The data processor may detect at least one sensor providing data to the data processor and determine a sensor type associated with each of the at least one sensor. The data processor may select a mode of operation based on the determined sensor type of the detected at least one sensor and of each of the at least one sensor. A first of the plurality of operating modes may be selected in response to determining that the at least one detected sensor includes a first sensor type or combination of sensor types. The data processor may be configured to receive data from the at least one detected sensor and process the received data according to the selected mode of operation to output a characterization of a user's sleep.
    Type: Application
    Filed: January 19, 2021
    Publication date: September 2, 2021
    Applicant: Resmed Sensor Technologies Limited
    Inventor: Benjamin RUBIN
  • Patent number: 11052057
    Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: July 6, 2021
    Assignees: MESHABERASE, LLC, The United States of America, as Represented by the Secretary, Dept of Health and Human Services
    Inventors: Benjamin Rubin, Raj Puri, Bharat Joshi
  • Publication number: 20210196652
    Abstract: Methods for treating or inhibiting dysfunctional tear syndrome (DTS) or symptoms associated therewith, and compositions for use in the methods.
    Type: Application
    Filed: December 11, 2020
    Publication date: July 1, 2021
    Applicant: MESHABERASE, LLC
    Inventor: Benjamin RUBIN
  • Publication number: 20210082305
    Abstract: System and method for a user to monitor and/or modify his or her sleep. In one embodiment, the sleep coaching system comprises a sensor for sensing a physiological signal of a sleeping user such as an EEG, computer memory databases for storing user and sleep-related data and advice, and a processor that generates a set of advice to improve user sleep satisfaction based on the user and sleep-related data. The advice to improve user sleep satisfaction, which may be communicated to the user, may comprise a sleep coaching plan, which may include one or more sleep coaching workshops that the user may undertake.
    Type: Application
    Filed: August 27, 2020
    Publication date: March 18, 2021
    Applicant: RESMED SENSOR TECHNOLOGIES LIMITED
    Inventors: David DICKINSON, Jason DONAHUE, Stephan FABREGAS, Benjamin RUBIN, John SHAMBROOM, Eric SHASHOUA
  • Publication number: 20200147010
    Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.
    Type: Application
    Filed: October 7, 2019
    Publication date: May 14, 2020
    Applicants: MESHABERASE, LLC, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES
    Inventors: Benjamin RUBIN, Raj PURI, Bharat JOSHI
  • Publication number: 20190142769
    Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.
    Type: Application
    Filed: January 10, 2019
    Publication date: May 16, 2019
    Applicants: MESHABERASE, LLC, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES
    Inventors: Benjamin RUBIN, Raj PURI, Bharat JOSHI
  • Publication number: 20180042870
    Abstract: The present disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or derivatives thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.
    Type: Application
    Filed: September 8, 2017
    Publication date: February 15, 2018
    Applicant: Meshaberase, LLC
    Inventors: Benjamin RUBIN, Raj PURI, Bharat JOSHI
  • Publication number: 20160184242
    Abstract: The present disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or derivatives thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.
    Type: Application
    Filed: March 9, 2016
    Publication date: June 30, 2016
    Inventors: Raj K. Puri, Bharat H. Joshi, Benjamin Rubin
  • Publication number: 20150051453
    Abstract: Systems and methods are provided for a multi-modal sleep system comprising a data processor for operating in a plurality of operating modes. The data processor may detect at least one sensor providing data to the data processor and determine a sensor type associated with each of the at least one sensor. The data processor may select a mode of operation based on the determined sensor type of the detected at least one sensor and of each of the at least one sensor. A first of the plurality of operating modes may be selected in response to determining that the at least one detected sensor includes a first sensor type or combination of sensor types. The data processor may be configured to receive data from the at least one detected sensor and process the received data according to the selected mode of operation to output a characterization of a user's sleep.
    Type: Application
    Filed: September 26, 2014
    Publication date: February 19, 2015
    Inventor: Benjamin Rubin
  • Patent number: 8870764
    Abstract: Systems and methods are provided for a multi-modal sleep system comprising a data processor for operating in a plurality of operating modes. The data processor may detect at least one sensor providing data to the data processor and determine a sensor type associated with each of the at least one sensor. The data processor may select a mode of operation based on the determined sensor type of the detected at least one sensor and of each of the at least one sensor. A first of the plurality of operating modes may be selected in response to determining that the at least one detected sensor includes a first sensor type or combination of sensor types. The data processor may be configured to receive data from the at least one detected sensor and process the received data according to the selected mode of operation to output a characterization of a user's sleep.
    Type: Grant
    Filed: September 6, 2011
    Date of Patent: October 28, 2014
    Assignee: ResMed Sensor Technologies Limited
    Inventor: Benjamin Rubin
  • Publication number: 20140314841
    Abstract: The present disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or derivatives thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.
    Type: Application
    Filed: April 18, 2014
    Publication date: October 23, 2014
    Applicant: The United States of America, as Represented by the Secretary, Department of Health and Human Serv
    Inventors: Raj K. Puri, Bharat H. Joshi, Benjamin Rubin
  • Publication number: 20130344465
    Abstract: System and method for a user to monitor and/or modify his or her sleep. In one embodiment, the sleep coaching system comprises a sensor for sensing a physiological signal of a sleeping user such as an EEG, computer memory databases for storing user and sleep-related data and advice, and a processor that generates a set of advice to improve user sleep satisfaction based on the user and sleep-related data. The advice to improve user sleep satisfaction, which may be communicated to the user, may comprise a sleep coaching plan, which may include one or more sleep coaching workshops that the user may undertake.
    Type: Application
    Filed: August 23, 2013
    Publication date: December 26, 2013
    Applicant: ResMed Sensor Technologies Limited
    Inventors: David Dickinson, Jason Donahue, Stephen Fabregas, Benjamin Rubin, John Shambroom, Eric Shashoua
  • Publication number: 20130060097
    Abstract: Systems and methods are provided for a multi-modal sleep system comprising a data processor for operating in a plurality of operating modes. The data processor may detect at least one sensor providing data to the data processor and determine a sensor type associated with each of the at least one sensor. The data processor may select a mode of operation based on the determined sensor type of the detected at least one sensor and of each of the at least one sensor. A first of the plurality of operating modes may be selected in response to determining that the at least one detected sensor includes a first sensor type or combination of sensor types. The data processor may be configured to receive data from the at least one detected sensor and process the received data according to the selected mode of operation to output a characterization of a user's sleep.
    Type: Application
    Filed: September 6, 2011
    Publication date: March 7, 2013
    Applicant: Zeo, Inc.
    Inventor: Benjamin Rubin
  • Publication number: 20100099954
    Abstract: System and method for a user to monitor and/or modify his or her sleep. In one embodiment, the sleep coaching system comprises a sensor for sensing a physiological signal of a sleeping user such as an EEG, computer memory databases for storing user and sleep-related data and advice, and a processor that generates a set of advice to improve user sleep satisfaction based on the user and sleep-related data. The advice to improve user sleep satisfaction, which may be communicated to the user, may comprise a sleep coaching plan, which may include one or more sleep coaching workshops that the user may undertake.
    Type: Application
    Filed: May 6, 2009
    Publication date: April 22, 2010
    Applicant: Zeo, Inc.
    Inventors: David Dickinson, Jason Donahue, Stephen Fabregas, Benjamin Rubin, John Shambroom, Eric Shashoua
  • Patent number: 7652070
    Abstract: A treatment method for pathologies in which increased levels of MMP production are implicated in pathogenesis. Examples of such pathologies include pterygium, kerataconus, and macular degeneration. Treatment is based on administration of cysteamine in therapeutically effective amounts. Treatment may be in one of several alternative forms, including eye drops and oral applications. Administration in the form of eye drops may be preferred for pathologies affecting the eyes.
    Type: Grant
    Filed: April 2, 2007
    Date of Patent: January 26, 2010
    Inventor: Benjamin Rubin
  • Publication number: 20080242735
    Abstract: A treatment method for pathologies in which increased levels of MMP production are implicated in pathogenesis. Examples of such pathologies include pterygium, kerataconus, and macular degeneration. Treatment is based on administration of cysteamine in therapeutically effective amounts. Treatment may be in one of several alternative forms, including eye drops and oral applications. Administration in the form of eye drops may be preferred for pathologies affecting the eyes.
    Type: Application
    Filed: April 2, 2007
    Publication date: October 2, 2008
    Inventor: Benjamin Rubin
  • Publication number: 20080127978
    Abstract: This invention relates to systems and methods for treating sleep apnea, which include a first dry electrode for detecting EEG signals of a user, positioned at or near a head of a user; a sleep stage processor for determining a sleep stage of the user based, at least in part, on the EEG signals detected by the first dry electrode, and a pressure delivery device for delivering a controllable stream of air to at least one of a nose and a mouth of the user, the stream of air having a pressure selected based, at least in part, on the sleep stage determined by the sleep stage processor.
    Type: Application
    Filed: December 5, 2007
    Publication date: June 5, 2008
    Inventors: Benjamin Rubin, Paolo DePetrillo
  • Publication number: 20070249952
    Abstract: Systems and methods for monitoring EEG signals include dry electrodes that can be used in sleep monitoring systems. In one aspect, a system for sleep stage monitoring and measurement includes a first dry electrode for detecting EEG signals of a user, a housing, and a sleep stage processor disposed within the housing. The first dry electrode is positioned at or near a head of the user. The sleep stage processor processes the EEG signals to determine a sleep stage of the user.
    Type: Application
    Filed: October 24, 2006
    Publication date: October 25, 2007
    Inventors: Benjamin Rubin, Paolo DePetrillo, Sheldon Provost, Daniel Rothman, Jason Donahue, Julie Penner
  • Publication number: 20070239187
    Abstract: A guard for use with a surgical cutting system. The guard includes a housing and wiring. The housing defines a longitudinal passageway, and is configured for releasable attachment to an instrument handpiece. The wiring is coupled to the housing and includes an electrically conductive wire and an insulative material. The wire defines opposing, first and second ends, with the first end being positioned within the passageway. The insulative material covers the wire apart from the first end such that the first end of the wire is exposed within the passageway. The first end of the wire establishes an electrical connection with a cutting tool shank upon placement within the passageway.
    Type: Application
    Filed: June 8, 2007
    Publication date: October 11, 2007
    Inventors: William Brunnett, Kevin McFarlin, Benjamin Rubin, Robert Vaccaro