Patents by Inventor Benjamin S. Isaacs

Benjamin S. Isaacs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of enhancing solubility of agents
    Publication number: 20080102109
    Abstract: This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions.
    Type: Application
    Filed: October 27, 2006
    Publication date: May 1, 2008
    Inventors: John G. Augustine, Kaliappanadar Nellaiappan, Benjamin S. Isaacs, Indu J. Isaacs
  • Methods of enhancing solubility of compounds
    Patent number: 7345093
    Abstract: This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various advantages over conventionally known compositions.
    Type: Grant
    Filed: April 27, 2004
    Date of Patent: March 18, 2008
    Assignee: Formatech, Inc.
    Inventors: John G. Augustine, Kaliappanadar Nellaiappan, Benjamin S. Isaacs, Indu J. Isaacs
  • Stabilized liquid anti-RSV antibody formulations
    Patent number: 7294336
    Abstract: The present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS® or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention.
    Type: Grant
    Filed: February 24, 2006
    Date of Patent: November 13, 2007
    Assignee: MedImmune, Inc.
    Inventors: Cynthia N. Oliver, Erica Shane, Benjamin S. Isaacs, Christian B. Allan, Stephen T. Chang
  • Stabilized liquid anti-RSV antibody formulations
    Patent number: 7132100
    Abstract: The present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS® or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention.
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: November 7, 2006
    Assignee: MedImmune, Inc.
    Inventors: Cynthia N. Oliver, Erica Shane, Benjamin S. Isaacs, Christian B. Allan, Stephen T. Chang
  • Working pipettor station
    Patent number: 5961927
    Abstract: The invention relates to a working pipettor station comprising an exterior frame and an interior support. The pipettor station is used in conjunction with a pipettor which is in use (i.e., with a pipettor tip attached) and requires temporary and secured positioning or storage. Optionally, an apron can be an additional component of the working pipettor station.
    Type: Grant
    Filed: December 23, 1996
    Date of Patent: October 5, 1999
    Assignee: Formatech, Inc.
    Inventors: Benjamin S. Isaacs, Rachel C. Isaacs, Katrina M. Brown, Joshua N. Isaacs, Jennifer L. Ray, Suzanne P. McKenzie, Heather E. Hughes
  • Pharmaceutical formulations of osteogenic proteins
    Patent number: 5597897
    Abstract: A composition comprising a pharmaceutically acceptable admixture of an osteogenic protein; a polymer matrix component selected from the group consisting of poly(lactic acid), poly(glycolic acid), and copolymers of lactic acid and glycolic acid; and an osteogenic protein-sequestering material.
    Type: Grant
    Filed: June 29, 1993
    Date of Patent: January 28, 1997
    Assignee: Genetics Institute, Inc.
    Inventors: Eyal Ron, Thomas J. Turek, Benjamin S. Isaacs, Himakshi Patel, Richard A. Kenley
  • Pharmaceutical formulations of plasminogen activator proteins
    Patent number: 4980165
    Abstract: Pharmaceutical formulations for intravenous bolus injection are presented that provide thrombolytic proteins, especially "second generation" tPA molecules, in relatively high concentrations at low concentrations of excipients.
    Type: Grant
    Filed: January 27, 1989
    Date of Patent: December 25, 1990
    Assignee: Genetics Institute, Inc.
    Inventors: Benjamin S. Isaacs, Himakshi Patel