Patents by Inventor Benjamin T. Gravely

Benjamin T. Gravely has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120088980
    Abstract: In an illustrative embodiment, an apparatus for imaging a portion of a mammalian eyelid has an eye contact lenspiece configured to direct the light through an eyelid from posterior to anterior surface to thereby trans-illuminate the eyelid, when the light source illuminates the contact lens. An imaging device receives an image of the eyelid as it is trans-illuminated. Other methods and apparatus are presented in various embodiments, hence this abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
    Type: Application
    Filed: December 14, 2011
    Publication date: April 12, 2012
    Applicant: TearScience, Inc.
    Inventors: Benjamin T. Gravely, Stephen M. Grenon, Timothy R. Willis, John M. Jans, Donald R. Korb
  • Publication number: 20120016275
    Abstract: An apparatus for treating meibomian gland dysfunction caused by meibomian gland obstruction in order to restore the natural flow of secretion from the meibomian gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Application
    Filed: September 23, 2011
    Publication date: January 19, 2012
    Applicant: TearScience, Inc.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely
  • Patent number: 8092023
    Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image. The second image can be subtracted from the first image to reduce and/or eliminate the background signal(s) in the first image to produce a resulting image. The resulting image can be processed and analyzed to measure a TFLT.
    Type: Grant
    Filed: April 1, 2010
    Date of Patent: January 10, 2012
    Assignee: TearScience, Inc.
    Inventors: Donald R. Korb, William L. Weber, Randal B. Chinnock, Benjamin T. Gravely, Stephen M. Grenon, Michael Zelina
  • Patent number: 8083787
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Grant
    Filed: May 15, 2006
    Date of Patent: December 27, 2011
    Assignee: TearScience, Inc.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely
  • Publication number: 20110285961
    Abstract: The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer.
    Type: Application
    Filed: August 1, 2011
    Publication date: November 24, 2011
    Applicant: TEARSCIENCE, INC.
    Inventors: Donald R. Korb, Benjamin T. Gravely
  • Patent number: 8025689
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: September 27, 2011
    Assignee: TearScience, Inc.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely
  • Patent number: 7988294
    Abstract: The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: August 2, 2011
    Assignee: TearScience, Inc.
    Inventors: Donald R. Korb, Benjamin T. Gravely
  • Publication number: 20110137214
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Application
    Filed: February 11, 2011
    Publication date: June 9, 2011
    Applicant: TEARSCIENCE, INC.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely, Stephen M. Grenon
  • Publication number: 20110130729
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Application
    Filed: February 11, 2011
    Publication date: June 2, 2011
    Applicant: TEARSCIENCE, INC.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely, Stephen M. Grenon
  • Publication number: 20100259722
    Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.
    Type: Application
    Filed: April 1, 2010
    Publication date: October 14, 2010
    Applicant: TearScience, Inc.
    Inventors: Donald R. Korb, William L. Weber, Randal B. Chinnock, Benjamin T. Gravely, Stephen M. Grenon
  • Publication number: 20100259723
    Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.
    Type: Application
    Filed: April 1, 2010
    Publication date: October 14, 2010
    Applicant: TearScience, Inc.
    Inventors: Donald R. Korb, William L. Weber, Randal B. Chinnock, Benjamin T. Gravely, Stephen M. Grenon, Michael Zelina
  • Publication number: 20100259721
    Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.
    Type: Application
    Filed: April 1, 2010
    Publication date: October 14, 2010
    Applicant: TearScience, Inc.
    Inventors: Donald R. Korb, William L. Weber, Randal B. Chinnock, Benjamin T. Gravely, Stephen M. Grenon, Michael Zelina
  • Publication number: 20100256552
    Abstract: A method and apparatus for treating gland dysfunction caused by gland obstruction in order to restore the natural flow of secretion from the gland comprises the application of a combination of energy, suction, vibration, heat, aspiration, chemical agents and pharmacological agents to loosen and thereafter remove the obstructive material.
    Type: Application
    Filed: June 23, 2010
    Publication date: October 7, 2010
    Applicant: TEARSCIENCE, INC.
    Inventors: Donald R. Korb, Timothy R. Willis, Benjamin T. Gravely
  • Publication number: 20100253907
    Abstract: Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for measuring a tear film layer thickness (TFLT) of the ocular tear film, including lipid layer thickness (LLT) and/or aqueous layer thickness (ALT). The measured TFLT can be used to diagnosis dry eye syndrome (DES). In certain disclosed embodiments, a multi-wavelength light source can be controlled to illuminate the ocular tear film. Light emitted from the multi-wavelength light source undergoes optical wave interference interactions in the tear film. An imaging device can be focused on the lipid layer of the tear film to capture optical wave interference interactions of specularly reflected light from the tear film combined with a background signal(s) in a first image. The imaging device can also be focused on the lipid layer of the tear film to capture a second image containing the background signal(s) present in the first image.
    Type: Application
    Filed: April 1, 2010
    Publication date: October 7, 2010
    Applicant: TearScience, Inc.
    Inventors: Donald R. Korb, William L. Weber, Randal B. Chinnock, Benjamin T. Gravely, Stephen M. Grenon
  • Patent number: 7758190
    Abstract: The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: July 20, 2010
    Assignee: TearScience, Inc.
    Inventors: Donald R. Korb, Benjamin T. Gravely
  • Publication number: 20100085540
    Abstract: The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer.
    Type: Application
    Filed: December 8, 2009
    Publication date: April 8, 2010
    Applicant: TearScience, Inc.
    Inventors: Donald R. Korb, Benjamin T. Gravely
  • Publication number: 20080319323
    Abstract: The invention comprises a method for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking. Light is directed to the lipid layer of a patient's eye with an illuminator. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. The specularly reflected light is collected and focused using a collector such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer.
    Type: Application
    Filed: September 11, 2007
    Publication date: December 25, 2008
    Inventors: Benjamin T. Gravely, Donald R. Korb
  • Publication number: 20080316499
    Abstract: The invention comprises an apparatus for measuring the relative thickness of the lipid layer component of the precorneal tear film on the surface of an eye after distribution of the lipid layer subsequent to blinking is disclosed. An illuminator directs light to the lipid layer of a patient's eye. The illuminator is a broad spectrum light source covering the visible region and is a lambertion light emitter such that the light source is specularly reflected from the lipid layer and undergoes constructive and destructive interference in the lipid layer. A collector collects and focuses the specularly reflected light such that the interference patterns on the tear film lipid layer are observable. The collector also produces an output signal representative of the specularly reflected light which is suitable for further analysis, such as projection on to a high resolution video monitor or analysis by or storage in a computer.
    Type: Application
    Filed: June 20, 2007
    Publication date: December 25, 2008
    Inventors: Donald R. Korb, Benjamin T. Gravely
  • Publication number: 20080081999
    Abstract: In an illustrative embodiment, an apparatus for imaging a portion of a mammalian eyelid has an eye contact lenspiece configured to direct the light through an eyelid from posterior to anterior surface to thereby trans-illuminate the eyelid, when the light source illuminates the contact lens. An imaging device receives an image of the eyelid as it is trans-illuminated. Other methods and apparatus are presented in various embodiments, hence this abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
    Type: Application
    Filed: August 17, 2007
    Publication date: April 3, 2008
    Inventors: Benjamin T. Gravely, Stephen M. Grenon, Timothy R. Willis, John M. Jans, Donald R. Korb
  • Publication number: 20080081996
    Abstract: A method of evaluating dry eye in humans wherein the flow of naturally occurring secretion to the eye is reduced or stopped due to the presence of an obstruction of a meibomian gland in the eyelid involves applying a pressure to the eyelid that mimics pressure applied during blinking; and simultaneously imaging the glands to diagnose the condition of the meibomian gland. This abstract is not to be considered limiting, since other embodiments may deviate from the features described in this abstract.
    Type: Application
    Filed: September 29, 2006
    Publication date: April 3, 2008
    Inventors: Stephen M. Grenon, Timothy R. Willis, Benjamin T. Gravely, Donald R. Korb