Patents by Inventor Benjamin T. Walters

Benjamin T. Walters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIPOLE MOMENT BASED COARSE GRAINED REPRESENTATION OF ANTIBODY ELECTROSTATICS
    Publication number: 20220148676
    Abstract: The present disclosure relates to polypeptide therapeutics, and in particular to techniques for prediction of polypeptide properties that may make for suitable polypeptide therapeutics using a model representative of electrostatics of a polypeptide. Particularly, aspects of the present disclosure are directed to ascertaining molecular multipole moments of an antibody molecule, creating a model of the antibody molecule by selecting sites within a representation of the antibody molecule, calculating a charge for each of the sites, where a combination of calculated charges for the sites approximates the molecular multipole moments of the antibody molecule, and simulating interactions of molecules in a solution. At least one molecule of the molecules in the solution is an instance of the model of the antibody molecule and the interactions are simulated based on the charges calculated for each of the sites within the representation of the antibody molecule.
    Type: Application
    Filed: January 28, 2022
    Publication date: May 12, 2022
    Applicant: GENENTECH, INC.
    Inventors: Saeed IZADI, Thomas W. PATAPOFF, Benjamin T. WALTERS
  • ANTI-KLK5 ANTIBODIES AND METHODS OF USE
    Publication number: 20210301032
    Abstract: The invention provides anti-KLK5 antibodies and methods of using the same.
    Type: Application
    Filed: November 17, 2020
    Publication date: September 30, 2021
    Applicant: Genentech, Inc.
    Inventors: Cecilia P.C. Chiu, Hilda Y. Hernandez-Barry, David B. Iaea, Moulay Hicham Alaoui-Ismaili, James T. Koerber, Wei Yu Lin, Kelly Loyet, Yonglian Sun, Benjamin T. Walters, Jawahar Sudhamsu
  • ANTI-KLK5 ANTIBODIES AND METHODS OF USE
    Publication number: 20200040103
    Abstract: The invention provides anti-KLK5 antibodies and methods of using the same.
    Type: Application
    Filed: March 13, 2019
    Publication date: February 6, 2020
    Applicant: Genentech, Inc.
    Inventors: Cecilia P. C. Chiu, Hilda Y. Hernandez-Barry, David B. Iaea, Moulay Hicham Alaoui-Ismaili, James T. Koerber, Wei Yu Lin, Kelly Loyet, Yonglian Sun, Benjamin T. Walters, Jawahar Sudhamsu