Abstract: The present disclosure relates to methods of purifying T cells, to T cells and T cell products produced by the methods, and use of the cells and products for therapy. In certain embodiments, the present disclosures provides a method of purifying T cells. The method comprises subjecting a medium comprising the T cells to inertial microfluidic fractionation and obtaining a fraction comprising purified T cells.

Abstract: Disclosed herein are pharmacologically acceptable magnetic nanoparticles suitable for administration to a subject.

Abstract: An electric actuator includes a casing having a base, on which an electric motor is fixed having a stator with radially extending straight teeth and having a plurality of coils and a rotor formed by a plurality of magnets. The coils extend in a plane parallel to the base of the casing and the rotor is extended by a pinion forming a worm gear with an axis perpendicular to the orientation of the coils. The worm gear meshes with a threaded rod extending parallel to the base of the casing, wherein the threaded rod is guided at the rear by a fixed smooth bearing or by a fixed nut, with the smooth bearing or nut being rigidly connected to a cover of the casing. The axial end of the worm gear is guided by the cover and a printed circuit, to which the plurality of coils is connected, is positioned between the stator and the threaded rod.

Abstract: The invention relates to a method for sensing target molecules in an analyte solution, a sensor for sensing target molecules in an analyte solution and a measurement system for sensing target molecules in an analyte solution. The method comprises providing a capture surface, wherein a plurality of capture molecules are arranged on the capture surface, each of the capture molecules being configured to bind to at least one of said target molecules. The method further comprises exposing the capture surface to the analyte solution to allow target molecules to bind to the capture molecules arranged on the capture surface.

Abstract: Provided is an apparatus for inducing and/or controlling flow of a fluid within a microchannel in a microfluidic device. The apparatus includes a fluid reservoir configured for holding a volume of fluid to be transported through said microfluidic channel and also configured for fluid connection to an inlet of said microfluidic channel. The apparatus also includes an evaporation reservoir configured for fluid connection to an outlet of said microfluidic channel. The evaporation reservoir includes at least one wetting, wicking or hydrophilic structure positioned at least partly within the reservoir. The wetting, wicking, or hydrophilic structure is capable of absorbing or conducting a fluid present in the microfluidic channel via wicking action or capillary force and maintaining a substantially constant volume of fluid in the evaporation reservoir.

Abstract: Disclosed herein are pharmacologically acceptable magnetic nanoparticles suitable for administration to a subject.

Abstract: An electric actuator includes a casing having a base, on which an electric motor is fixed having a stator with radially extending straight teeth and having a plurality of coils and a rotor formed by a plurality of magnets. The coils extend in a plane parallel to the base of the casing and the rotor is extended by a pinion forming a worm gear with an axis perpendicular to the orientation of the coils. The worm gear meshes with a threaded rod extending parallel to the base of the casing, wherein the threaded rod is guided at the rear by a fixed smooth bearing or by a fixed nut, with the smooth bearing or nut being rigidly connected to a cover of the casing. The axial end of the worm gear is guided by the cover and a printed circuit, to which the plurality of coils is connected, is positioned between the stator and the threaded rod.

Abstract: An electric actuator includes a threaded rod turned by a motor, the threaded rod having a drive zone extended on each side by threaded zones, one of the threaded zones collaborating with a stationary nut and the other of the threaded zones collaborating with a nut secured to a control member capable of translational movement along an axis parallel to the axis of the threaded zone, the threaded rod being moved with a helical motion.

Abstract: Disclosed is a magnetic sensor for measuring flux density. The sensor comprises at least one tunnelling magnetoresistor, supporting circuitry and an output for outputting a signal from the tunnelling magnetoresistor. In another aspect, there is also provided a sensor probe comprising at least one magnetic sensor. A magnetic probe system is also described, comprising the probe sensor and processing circuitry. Methods of processing the output signal from the magnetic sensor are also described. In one application, the system and method allow for detection of tissue such as lymph nodes that have taken up small quantities of magnetic particles upon injection of a magnetic tracer containing the magnetic particles into a patient, and can be used to identify such tissue that could be affected by certain forms of cancer.

Abstract: Disclosed is a magnetic sensor for measuring flux density. The sensor comprises at least one tunnelling magnetoresistor, supporting circuitry and an output for outputting a signal from the tunnelling magnetoresistor. In another aspect, there is also provided a sensor probe comprising at least one magnetic sensor. A magnetic probe system is also described, comprising the probe sensor and processing circuitry. Methods of processing the output signal from the magnetic sensor are also described. In one application, the system and method allow for detection of tissue such as lymph nodes that have taken up small quantities of magnetic particles upon injection of a magnetic tracer containing the magnetic particles into a patient, and can be used to identify such tissue that could be affected by certain forms of cancer.

Abstract: An electric actuator includes a threaded rod turned by a motor, the threaded rod having a drive zone extended on each side by threaded zones, one of the threaded zones collaborating with a stationary nut and the other of the threaded zones collaborating with a nut secured to a control member capable of translational movement along an axis parallel to the axis of the threaded zone, the threaded rod being moved with a helical motion.

Abstract: An optical system for a motor vehicle, the optical system performing at least one main optical function and including in particular a diffusion screen, at least one light source of the LED type, each LED of the optical system producing a set of rays of light to be propagated in the diffusion screen wherein the screen is in the form of a curved sheet, with an upper lateral flange and a lower lateral flange which meet at a periphery which has in particular a rear face and a front edge and the principal function is performed essentially via an output face constituted by the front edge of the diffusion screen.

Abstract: An optical system for a motor vehicle, the optical system performing at least one main optical function and including in particular a diffusion screen, at least one light source of the LED type, each LED of the optical system producing a set of rays of light to be propagated in the diffusion screen wherein the screen is in the form of a curved sheet, with an upper lateral flange and a lower lateral flange which meet at a periphery which has in particular a rear face and a front edge and the principal function is performed essentially via an output face constituted by the front edge of the diffusion screen.

Abstract: An assembly of at least two electric boards, and in particular two printed circuit boards, the two boards being welded to one another, wherein at least one of the two boards comprises at least one orifice which shows a trace of the welding.

Abstract: An optical system for a motor vehicle, the optical system performing at least one main optical function and including in particular a diffusion screen, at least one light source of the LED type, each LED of the optical system producing a set of rays of light to be propagated in the diffusion screen wherein the screen is in the form of a curved sheet, with an upper lateral flange and a lower lateral flange which meet at a periphery which has in particular a rear face and a front edge and the principal function is performed essentially via an output face constituted by the front edge of the diffusion screen.

Abstract: A lighting or signalling device in which a particular output unit of the device in question is formed, the output unit consisting of a stack of screens, independent of one another; each screen comprises a plurality of optical patterns produced in its thickness, able to divert light signals emitted by a light source; the spread of the light beam emerging from the device in question is thus adjustable in a first diffusion direction (OX), corresponding, for each screen in question, to a direction parallel to a plane defined by the screen and containing the optical patterns, and in a second diffusion direction (OZ), corresponding to a direction parallel to a plane roughly perpendicular to the planes defined by the screens, the spread on the second diffusion plane depending on the relative positions of the various screens. In this way in particular a “block of illuminated material” effect is obtained.