Patents by Inventor Benjamin Vieira

Benjamin Vieira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY-OLIGONUCLEOTIDE COMPLEXES AND USES THEREOF
    Publication number: 20240100177
    Abstract: Provided herein are oligonucleotide-antibody complexes, methods of preparing the complexes, and methods of using the complexes (e.g., treating muscle diseases). In particular, provided are compounds of Formula (I) and various methods for the preparation of the compounds. Also provided are pharmaceutical compositions comprising compounds of Formula (I) and methods of treating muscle disease in a subject by administering a compound or composition described herein.
    Type: Application
    Filed: December 3, 2021
    Publication date: March 28, 2024
    Applicant: Dyne Therapeutics, Inc.
    Inventors: Scott Hilderbrand, John Najim, Qifeng Qiu, Benjamin Vieira, Timothy Weeden, Sean Spring
  • METHODS OF PREPARING PROTEIN-OLIGONUCLEOTIDE COMPLEXES
    Publication number: 20230330562
    Abstract: Aspects of the disclosure relate to methods of purifying complexes comprising a protein (e.g., antibody) covalently linked to a molecular payload (e.g., a charge-neutral oligonucleotide, a charged oligonucleotide, or a hydrophobic small molecule) using mixed-mode resin that comprises positively-charged metal sites and negatively charged ionic sites, e.g., hydroxyapatite resin. Methods of producing the complexes are also provided.
    Type: Application
    Filed: September 3, 2021
    Publication date: October 19, 2023
    Applicant: Dyne Therapeutics, Inc.
    Inventors: Timothy Weeden, Scott Hilderbrand, Sean Spring, Peiyi Shen, Benjamin Vieira