Abstract: A torque transmitting device for a drivetrain for transmitting a drive torque to an output element. The device having: an electric motor with a conversion unit, which comprises a stator and a rotor that is rotatable relative to the stator, for converting electrical energy into mechanical energy; and a torsional vibration damper with a damper mass received on a damper mass support such that the damper mass can be deflected to a limited extent against the action of a restoring force, the damper mass being arranged so as to overlap radially with the conversion unit.

Abstract: A torque transmitting device for a drive train for transmitting an input torque provided by at least one drive element to an output element. The device including: an electric motor having a stator and a rotor which can be rotated relative to said stator for providing a further drive torque; a separating clutch arranged operatively between the first drive element and the electric motor; and at least one centrifugal pendulum which is arranged operatively between the separating clutch and the output element and has at least two pendulum masses which are accommodated so as to be deflectable to a limited extent along a pendulum path and so as to be peripherally adjacent to one another on at least one pendulum mass carrier that can be rotated about an axis of rotation, wherein the peripherally adjacent pendulum masses are coupled to one another via coupling means.

Abstract: The present invention relates to methods of determining the presence or absence of certain cancers in a human individual, as well as to related methods to determine the response to therapy against certain cancers in a human individual, in particular ovarian cancer in a woman. Such methods are based on the detection-from (eg cell-free) DNA of said human individual—of one or more methylated (or un-methylated) CpGs being associated with differentially methylated regions (DMRs) of the present invention; such as methylation (or un-methylation) at one or more or all of certain CpGs being associated with such DMRs. Accordingly, such methods have diagnostic, prognostic and/or predictive utility for detecting or managing certain cancers in women or men, in particular ovarian cancer in women.

Abstract: The present invention relates to methods of determining the presence or absence of an ovarian cancer in a woman, as well as to related methods to determine the response to therapy against ovarian cancer in a woman. Such methods are based on the detection—from cell-free DNA of said woman—of one or more methylated (or un-methylated) CpGs being associated with differentially methylated regions (DMRs) of the present invention;such as methylation (or un-methylation) at one or more or all of certain CpGs being associated with such DMRs. Accordingly, such methods have diagnostic, prognostic and/or predictive utility for detectingor managing ovarian cancer in women.