Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of NETs in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating NET mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRI)). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of NET mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g., mCBS.

Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.

Abstract: The present disclosures are directed to personal care compositions comprising crosslinked silicone elastomer; personal care compositions comprising a crosslinked silicone elastomer powder that is free of surfactant; and personal care compositions that are free of a polyether compound. The present disclosures are further directed to personal care compositions comprising one or more of oils, an aqueous phase, sunscreens, film formers, waxes, emulsifiers, particulates, pigments, dyes, and preservatives.

Abstract: Diagnosis, treatment and prophylaxis of diseases and conditions associated with smooth muscle cell (SMC) dysfunction are provided through the inhibition or IL-11-mediated signalling.

Abstract: The invention relates to a method for providing at least one piece of information about a hydraulic apparatus (1), wherein the following stages are performed: Performing a detection (201) of detection values (210) at the apparatus (1), wherein the detection values (210) are specific for measurements at different measuring points and at different apparatus components (120) of the apparatus (1), Performing a transmission (202) of the detected detection values (210) to a processing component (300), Providing an apparatus information (211) about a specification of the apparatus (1) and/or the measurements, wherein providing the apparatus information (211) is performed at the processing component (300) to provide the transmitted detection values (210) with the apparatus information (211).

Abstract: Diagnosis, treatment and prophylaxis of diseases and conditions associated with smooth muscle cell (SMC) dysfunction are provided through the inhibition of IL-11-mediated signalling.

Abstract: An electric motor, in particular a separately excited synchronous motor, has a rotor shaft with at least one slip ring and at least one electrically conductive contact element, in particular a carbon brush, which bears against the slip ring and is accommodated in a channel-like guide formed in a housing and extending radially with respect to the rotor shaft and which carbon brush is radially tensioned against the slip ring by means of a spring element, wherein a roller is provided which is tensioned laterally against the contact element via a further spring element and via which the contact element is tensioned against a wall of the guide.

Abstract: An electric motor, in particular a separately excited synchronous motor, comprises a rotor shaft with at least one slip ring and at least one electrically conductive contact element, in particular a carbon brush, which bears against the slip ring and is accommodated in a channel-like guide formed in a housing and extending radially with respect to the rotor shaft and which carbon brush is radially tensioned against the slip ring by means of a spring element, wherein a roller is provided which is tensioned laterally against the contact element via a further spring element and via which the contact element is tensioned against a wall of the guide.

Abstract: Diagnosis, treatment and prophylaxis of diseases and conditions associated with smooth muscle cell (SMC) dysfunction are provided through the inhibition of IL-11-mediated signalling.