Patents by Inventor Benjamin Woolven

Benjamin Woolven has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY DISORDERS
    Publication number: 20090258012
    Abstract: The invention relates to compositions and methods for treating inflammatory disorders. More specifically, the invention relates to antibody compositions and their use in the treatment of inflammatory disorders.
    Type: Application
    Filed: March 24, 2009
    Publication date: October 15, 2009
    Applicant: Domantis Limited
    Inventors: Olga Ignatovich, Rudolf Maria Theodora de Wildt, Benjamin Woolven, Steven Grant, Philip C. Jones, Amrik Basran, Neil Brewis
  • DOMAIN ANTIBODY CONSTRUCT
    Publication number: 20070202105
    Abstract: The present invention provides a domain antibody construct which binds to human TNF-?, the construct comprising: (a) a domain antibody (dAb) which binds to human TNF-?; (b) a modified hinge region sequence; (c) a human or primate heavy chain constant region sequence having a truncated CH1 domain of not more than 20 residues, wherein said modified hinge region sequence contains either a deletion or a single amino acid substitution of at least one cysteine residue which normally facilitates disulfide bond formation between heavy and light antibody chains.
    Type: Application
    Filed: February 1, 2007
    Publication date: August 30, 2007
    Applicant: Peptech Limited
    Inventors: ANTHONY DOYLE, Benjamin Woolven, Jennifer Lee, Ian Tomlinson, Philip Jennings
  • Compositions and methods for treating inflammatory disorders
    Publication number: 20060073141
    Abstract: The invention relates to compositions and methods for treating inflammatory disorders. More specifically, the invention relates to antibody compositions and their use in the treatment of inflammatory disorders.
    Type: Application
    Filed: April 4, 2005
    Publication date: April 6, 2006
    Inventors: Olga Ignatovich, Rudolf de Wildt, Benjamin Woolven, Steven Grant, Philip Jones, Amrik Basran, Neil Brewis
  • Tumor Necrosis Factor Receptor 1 antagonists and methods of use therefor
    Publication number: 20060002935
    Abstract: The invention provides methods for treating inflammatory diseases (e.g., chronic inflammatory diseases) comprising administering an antagonist of Tumor Necrosis Factor Receptor 1. The invention also provides antagonists of Tumor Necrosis Factor Receptor 1, such as ligands that contain an immunoglobulin single variable domain or domain antibody (dAb) monomer that binds Tumor Necrosis Factor Receptor 1, and methods of using the ligands. Also provided are nucleic acids encoding the ligands, recombinant host cells and methods for preparing the ligands.
    Type: Application
    Filed: November 10, 2004
    Publication date: January 5, 2006
    Applicant: Domantis Limited
    Inventors: Neil Brewis, Benjamin Woolven, Steve Holmes, Ian Tomlinson
  • Compositions and methods for treating inflammatory disorders
    Publication number: 20050271663
    Abstract: The invention relates to compositions and methods for treating inflammatory disorders. More specifically, the invention relates to antibody compositions and their use in the treatment of inflammatory disorders.
    Type: Application
    Filed: August 24, 2004
    Publication date: December 8, 2005
    Inventors: Olga Ignatovich, Rudolf de Wildt, Benjamin Woolven, Steven Grant, Philip Jones, Amrik Basran, Neil Brewis