Abstract: The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a melanoma; an ovarian cancer; or a colorectal cancer). More specifically, the invention concerns the treatment of patients having cancer with an anti-TIGIT antagonist antibody, including treatment with an anti-TIGIT antagonist antibody in a combination therapy.

Abstract: The present application relates to embodiments for detecting firewall drift. In some embodiments, a first set of firewall rules of a first firewall for a first instance of a distributed application, a second set of firewall rules of a second firewall for a second instance of the distributed application, and a mapping of IP addresses to identifiers of services from amongst a first set of services of the first instance and a second set of services of the second instance may be obtained. First connectivity data and second connectivity data may be generated indicating, for each of IP address associated with the first and second set of firewall rules, a respective port number over which communications between a respective IP address are transmitted, and generating comparison data indicating whether firewall drift is detected based on a comparison of the first connectivity data and the second connectivity data.

Abstract: The present application relates to embodiments for detecting firewall drift. In some embodiments, a first set of firewall rules of a first firewall for a first instance of a distributed application, a second set of firewall rules of a second firewall for a second instance of the distributed application, and a mapping of IP addresses to identifiers of services from amongst a first set of services of the first instance and a second set of services of the second instance may be obtained. First connectivity data and second connectivity data may be generated indicating, for each of IP address associated with the first and second set of firewall rules, a respective port number over which communications between a respective IP address are transmitted, and generating comparison data indicating whether firewall drift is detected based on a comparison of the first connectivity data and the second connectivity data.

Abstract: The present application relates to embodiments for detecting firewall drift. In some embodiments, a first set of firewall rules of a first firewall for a first instance of a distributed application, a second set of firewall rules of a second firewall for a second instance of the distributed application, and a mapping of IP addresses to identifiers of services from amongst a first set of services of the first instance and a second set of services of the second instance may be obtained. First connectivity data and second connectivity data may be generated indicating, for each of IP address associated with the first and second set of firewall rules, a respective port number over which communications between a respective IP address are transmitted, and generating comparison data indicating whether firewall drift is detected based on a comparison of the first connectivity data and the second connectivity data.

Abstract: An organ lengthening device comprising a spring-like structure, wherein the surface of the device is covered with micron-size anchors such as hooks, studs or wires made from a biodegradable polymer. The anchors are configured to engage the surface of the organ so that the device will be anchored to the organ. The device, which is inserted into the organ in a compressed position, gradually lengthens over time, thereby lengthening the organ, wherein the anchors are configured to degrade away and eventually allow the device to become disengaged from the organ.

Abstract: In various embodiments, an inference application reconstructs representations of items in a spectral domain. The inference application maps a first set of data points associated with a both an item and the spectral domain to conditioning information via a first trained machine learning model. The inference application updates a second trained machine learning model based on the conditioning information to generate a model that represents the item within the spectral domain. The inference application generates a second set of data points associated with both the item and the spectral domain via the model. The inference application constructs an image associated with the item based on the second set of data points.

Abstract: In various embodiments, a training application generates a trained machine learning model that represents items in a spectral domain. The training application executes a first neural network on a first set of data points associated with both a first item and the spectral domain to generate a second neural network. Subsequently, the training application generates a set of predicted data points that are associated with both the first item and the spectral domain via the second neural network. The training application generates the trained machine learning model based on the first neural network, the second neural network, and the set of predicted data points. The trained machine learning model maps one or more positions within the spectral domain to one or more values associated with an item based on a set of data points associated with both the item and the spectral domain.

Abstract: In various embodiments, an inference application constructs medical images. The inference application executes a first trained machine learning model on a set of data points associated with a both a medical item and a spectral domain to generate a second model that represents the medical item within the spectral domain. The inference application maps a set of positions to a set of predicted values associated with both the medical item and the spectral domain via the second model. The inference application constructs an image of the medical item based on the first set of predicted values.

Abstract: To assist a machine learning environment in modelling a complex physical simulation (such as a numerical simulation or physics simulation), a correlation between input coordinates is determined. For example, a discrete solution (e.g., the correlation between the plurality of input coordinates) may be obtained from a non-discrete (e.g., continuous) physics space by performing a conversion from the physics space to a grid space. This correlation is input along with the coordinates into a machine learning environment to obtain results from the simulation. As a result, instead of implementing resource and power-intensive simulations to solve these computation problems, a machine learning environment implemented using less power and computing resources may solve these computation problems in a faster and more efficient manner.

Abstract: Methods and systems for processing data to distinguish between a plurality of conditions in lung ultrasound images and, in particular, lung ultrasound images containing B lines. Neural network systems and methods, in which the processor is trained using lung ultrasound images to distinguish between acute respiratory distress syndrome due to COVID-19, acute respiratory distress syndrome due to non-COVID-19 causes, and hydrostatic pulmonary edema.

Abstract: The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a melanoma; an ovarian cancer; or a colorectal cancer). More specifically, the invention concerns the treatment of patients having cancer with an anti-TIGIT antagonist antibody, including treatment with an anti-TIGIT antagonist antibody in a combination therapy.

Abstract: The application discloses an implantable device, comprising a galvanic redox system formed on a body substrate of the implantable device. The implantable device has a non-zero surface potential when it is deployed. The galvanic redox system comprises a first metal site and a second metal site, the first metal site comprising a first metal having a first metal electrode potential (FMEP) and the second metal site comprising a second metal having a second metal electrode potential (SMEP), which FMEP being lower than SMEP and SMEP being substantially different such that the implantable device is galvanized when it is deployed. Methods of making and using the implantabe device are also disclosed.

Abstract: An organ lengthening device comprising a spring-like structure, wherein the surface of the device is covered with micron-size anchors such as hooks, studs or wires made from a biodegradable polymer. The anchors are configured to engage the surface of the organ so that the device will be anchored to the organ. The device, which is inserted into the organ in a compressed position, gradually lengthens over time, thereby lengthening the organ, wherein the anchors are configured to degrade away and eventually allow the device to become disengaged from the organ.

Abstract: A differential global positioning system (DGPS) processor can include an almost fixed integer ambiguity (AFIA) module for generating in real-time a multiple dimensional state vector of integer ambiguities and multiple dimensional corrections. The AFIA module can use double difference (DD) measurements for pseudo-range (PR) and carrier phase (CP) pairs generated from at least three global positioning system (GPS) receivers. A DGPS processor can be included in a high data rate real time attitude determination (RTAD) system to achieve high heading accuracy with high integrity.

Abstract: Liquid titanium oxide compositions, methods for forming such compositions, and methods for etching material layers using such compositions are provided. In accordance with an exemplary embodiment, a liquid titanium oxide composition contains a solvent system, an organotitanate, and a high boiling point solvent having a boiling point in the range of about 140° C. to about 400° C.

Abstract: A system includes a client device and a server including a communication module configured to be accessed by the client device through which a user of the client device connects to another user via one of a plurality of communication services connected to the server, wherein one of the plurality of communication services is telephony.

Abstract: A differential global positioning system (DGPS) processor can include an almost fixed integer ambiguity (AFIA) module for generating in real-time a multiple dimensional state vector of integer ambiguities and multiple dimensional corrections. The AFIA module can use double difference (DD) measurements for pseudo-range (PR) and carrier phase (CP) pairs generated from at least three global positioning system (GPS) receivers. A DGPS processor can be included in a high data rate real time attitude determination (RTAD) system to achieve high heading accuracy with high integrity.

Abstract: A method and system for monitoring and managing applications and services. A repository comprising information identifying a plurality of assets and one or more relationships among the assets is maintained. One or more assets used to support an application are identified, along with one or more applications that are included in a service. Event and performance data are collected by a plurality of tools that perform monitoring and/or managing of the identified assets, the application, and/or the service. The gathered event and performance data is aggregated. The user is provided with a portal to access the aggregated event and performance data. Through this portal, the user can determine an impact of an event or a performance issue on the application or service based on the aggregated event or performance data and the relationships among the assets.

Abstract: A method and system for monitoring and managing applications and services. A repository comprising information identifying a plurality of assets and one or more relationships among the assets is maintained. One or more assets used to support an application are identified, along with one or more applications that are included in a service. Event and performance data are collected by a plurality of tools that perform monitoring and/or managing of the identified assets, the application, and/or the service. The gathered event and performance data is aggregated. The user is provided with a portal to access the aggregated event and performance data. Through this portal, the user can determine an impact of an event or a performance issue on the application or service based on the aggregated event or performance data and the relationships among the assets.

Abstract: A method and system for monitoring and managing applications and services. A repository comprising information identifying a plurality of assets and one or more relationships among the assets is maintained. One or more assets used to support an application are identified, along with one or more applications that are included in a service. Event and performance data are collected by a plurality of tools that perform monitoring and/or managing of the identified assets, the application, and/or the service. The gathered event and performance data is aggregated. The user is provided with a portal to access the aggregated event and performance data. Through this portal, the user can determine an impact of an event or a performance issue on the application or service based on the aggregated event or performance data and the relationships among the assets.