Abstract: An improved carrier system is provided that includes a plurality of carriers and/or a transport surface having anti-microbial characteristics. In a pneumatic tube carrier system application, the internal surfaces of one or a plurality of selectively openable/closeable carriers may comprise an anti-microbial material The anti-microbial material may be mixed with a base material to form each carrier. Alternatively, the anti-microbial material may be mixed in a coating applied to a base carrier structure. The carrier contact surfaces of the pneumatic tubes and other system componentry may also comprise an anti-microbial material.