Patents by Inventor Benno Guggenheimer
Benno Guggenheimer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9040284Abstract: Systems and methods of sample processing and temperature control are disclosed. The invention may especially relate to temperature control, and may in some embodiments be methods of temperature control of an automated sample processing system and methods of automated sample processing. Specifically, the present invention provides temperature control in relation to sample processing systems and methods of processing samples, and in some embodiments provides temperature control in relation to sample carriers and processing materials such as reagents. Corresponding systems and devices are disclosed, including sample processing systems (1), sample carrier temperature regulation systems (60), reagent temperature regulation systems, sample processing control systems, and temperature regulation devices, among other embodiments.Type: GrantFiled: September 24, 2012Date of Patent: May 26, 2015Assignee: DAKO DENMARK A/SInventors: Kristopher Buchanan, Marc Key, John Favuzzi, Rosanne Welcher, Benno Guggenheimer, Robert Clark, Michael Barber, Bob Lathrop
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Publication number: 20140286838Abstract: The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.Type: ApplicationFiled: June 9, 2014Publication date: September 25, 2014Inventors: Lars Winther, Marc Key, Kristopher Buchanan, John Favuzzi, Benno Guggenheimer
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Patent number: 8784735Abstract: The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as a slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.Type: GrantFiled: August 12, 2013Date of Patent: July 22, 2014Assignee: Dako Denmark A/SInventors: Lars Winther, Marc Key, Kristopher Buchanan, John Favuzzi, Benno Guggenheimer
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Publication number: 20130330252Abstract: The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as a slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.Type: ApplicationFiled: August 12, 2013Publication date: December 12, 2013Inventors: Lars Winther, Marc Key, Kristopher Buchanan, John Favuzzi, Benno Guggenheimer
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Patent number: 8529836Abstract: The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as a slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.Type: GrantFiled: June 11, 2012Date of Patent: September 10, 2013Assignee: DAKO Denmark A/SInventors: Lars Winther, Marc Key, Kristopher Buchanan, John Favuzzi, Benno Guggenheimer
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Publication number: 20120310422Abstract: The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as a slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.Type: ApplicationFiled: June 11, 2012Publication date: December 6, 2012Inventors: Lars Winther, Marc Key, Kristopher Buchanan, John Favuzzi, Benno Guggenheimer
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Patent number: 8298815Abstract: Systems and methods of sample processing and temperature control are disclosed. The invention may especially relate to temperature control, and may in some embodiments be methods of temperature control of an automated sample processing system and methods of automated sample processing. Specifically, the present invention provides temperature control in relation to sample processing systems and methods of processing samples, and in some embodiments provides temperature control in relation to sample carriers and processing materials such as reagents. Corresponding systems and devices are disclosed, including sample processing systems (1), sample carrier temperature regulation systems (60), reagent temperature regulation systems, sample processing control systems, and temperature regulation devices, among other embodiments.Type: GrantFiled: December 22, 2003Date of Patent: October 30, 2012Assignee: DAKO Denmark A/SInventors: Kristopher Buchanan, Marc Key, John Favuzzi, Rosanne Welcher, Benno Guggenheimer, Robert Clark, Michael Barber, Bob Lathrop
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Patent number: 8216512Abstract: The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as a slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.Type: GrantFiled: December 19, 2003Date of Patent: July 10, 2012Assignee: DAKO Denmark A/SInventors: Lars Winther, Marc Key, Kristopher S. Buchanan, John Favuzzi, Benno Guggenheimer
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Patent number: 7758809Abstract: The present invention concerns a method and an apparatus for automatic staining of at least one tissue sample accommodated on a slide by applying reagents. The system may include at least one slide provided in a slide rack, a fluid containment element, a slide holder, a vertical slide positioner to pivot the slides to a vertical position, and a slide immerser element to immerse the vertical slide into a fluid containment element or even a dip tank. By pivoting the slides from a horizontal to a vertical position, an automated method and apparatus for carrying out a pretreatment in an automated staining apparatus may be provided. The pivoting of slides may ensure an appropriate orientation of the slides for both the pretreatment and the staining processes.Type: GrantFiled: December 3, 2009Date of Patent: July 20, 2010Assignee: Dako Cytomation Denmark A/SInventors: John Favuzzi, Benno Guggenheimer, Jeff Rau, Marc Key, Robert Lathrop, Rosanne Welcher
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Publication number: 20100081167Abstract: The present invention concerns a method and an apparatus for automatic staining of at least one tissue sample accommodated on a slide by applying reagents. The system may include at least one slide provided in a slide rack, a fluid containment element, a slide holder, a vertical slide positioner to pivot the slides to a vertical position, and a slide immerser element to immerse the vertical slide into a fluid containment element or even a dip tank. By pivoting the slides from a horizontal to a vertical position, an automated method and apparatus for carrying out a pretreatment in an automated staining apparatus may be provided. The pivoting of slides may ensure an appropriate orientation of the slides for both the pretreatment and the staining processes.Type: ApplicationFiled: December 3, 2009Publication date: April 1, 2010Inventors: John Favuzzi, Benno Guggenheimer, Jeff Rau, Marc Key, Robert Lathrop, Rosanne Welcher
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Patent number: 7648678Abstract: The present invention concerns a method and an apparatus for automatic staining of at least one tissue sample accommodated on a slide by applying reagents. The system may include at least one slide provided in a slide rack, a fluid containment element, a slide holder, a vertical slide positioner to pivot the slides to a vertical position, and a slide immerser element to immerse the vertical slide into a fluid containment element or even a dip tank. By pivoting the slides from a horizontal to a vertical position, an automated method and apparatus for carrying out a pretreatment in an automated staining apparatus may be provided. The pivoting of slides may ensure an appropriate orientation of the slides for both the pretreatment and the staining processes.Type: GrantFiled: December 8, 2003Date of Patent: January 19, 2010Assignee: DAKO Denmark A/SInventors: John Favuzzi, Benno Guggenheimer, Jeff Rau, Marc Key, Robert Lathrop, Rosanne Welcher
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Publication number: 20060105359Abstract: The present invention concerns a method and apparatus for automatic processing a biological sample on a carrier, perhaps robotically, by applying predetermined amounts of reagents in a predetermined sequence according to a processing protocol, the processing including pre-treatment steps, under the control of an adaptive processing control system using a sample process parameter input that may be independent and an independent process parameter memory that does not interrupt process operation when being used, such that samples may be added or removed without interrupting the processing of other samples. Also included is an image capture function for sample and reagent identification and process monitoring, as well as temperature regulation and environmental control functions.Type: ApplicationFiled: June 20, 2005Publication date: May 18, 2006Applicant: DakoCytomation Denmark A/SInventors: John Favuzzi, Kristopher Buchanan, Michael Barber, Loren Bland, Dawn Rohrbacker, Robert Clark, Gordon Feingold, Benno Guggenheimer, Marc Key, Merritt Martin, Robert Lathrop, Jeffery Rau, Jonathan Sweda, Douglas Sweet, John Van Bosch, Lars Winther, Rosanne Welcher
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Publication number: 20060045806Abstract: The present invention concerns an apparatus for automatic processing at least one biological sample accommodated on a carrier member, such as a slide by applying a predetermined amount of reagents in a predetermined sequence according to a processing protocol, said apparatus comprising; a housing frame; at least one processing section for accommodating at least one slide, the at least one processing section is provided within the housing; a hood cover protecting the at least one processing section in said housing; wherein the hood cover completely encloses the processing section defining an interior space; and wherein the apparatus further comprises climate control device provided to control the environment within the interior space.Type: ApplicationFiled: December 19, 2003Publication date: March 2, 2006Applicant: DakoCytomation Denmark A/SInventors: Lars Winther, Marc Key, Kristopher Buchanan, John Favuzzi, Benno Guggenheimer
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Publication number: 20050064535Abstract: The present invention concerns a method and an apparatus for automatic staining of at least one tissue sample accommodated on a slide by applying reagents. The system may include at least one slide provided in a slide rack, a fluid containment element, a slide holder, a vertical slide positioner to pivot the slides to a vertical position, and a slide immerser element to immerse the vertical slide into a fluid containment element or even a dip tank. By pivoting the slides from a horizontal to a vertical position, an automated method and apparatus for carrying out a pretreatment in an automated staining apparatus may be provided. The pivoting of slides may ensure an appropriate orientation of the slides for both the pretreatment and the staining processes.Type: ApplicationFiled: December 8, 2003Publication date: March 24, 2005Applicant: Dako Cytomation Denmark A/SInventors: John Favuzzi, Benno Guggenheimer, Jeff Rau, Marc Key, Robert Lathrop, Rosanne Welcher
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Patent number: 6809823Abstract: An optical system for detecting and coupling light to optical devices, and a method for aligning and calibrating the system. The system includes positioning stages and fiber sensors. The fiber sensors are used to detect the positions of calibration pieces and other sensors in a variety of configurations. From these detected positions, any misalignment of the sensors or positioning stages may be calculated and corrected for. The fiber sensors calibrate the system.Type: GrantFiled: September 28, 2001Date of Patent: October 26, 2004Assignee: Agilent Technologies, Inc.Inventors: William P Kennedy, John Bernard Medberry, David Washburn, Benno Guggenheimer, James D Adams
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Patent number: 6806484Abstract: An edge detector with sub-micron accuracy. The edge detector comprises two single mode optical fibers with an optical path between them. One fiber is coupled to a laser light source, and creates a light beam. The other fiber is coupled to an optical power detector. The optical power reaching the optical power detector is determined by how much of the light beam is obscured by an object. Thus the position of the edge of the object may be determined from the optical power measured by the detector. The edge of an object may be positioned automatically according to the optical power measured by the detector.Type: GrantFiled: August 22, 2001Date of Patent: October 19, 2004Assignee: Agilent Technologies, Inc.Inventors: Edward Steketee, John Bernard Medberry, Benno Guggenheimer
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Patent number: 6778740Abstract: Fiber optic alignment methods and apparatus in accordance with the present invention first identify a target beam width incidence on an end of an optical element. The end of the optical element is placed into a beam of light at an axial location relative to the beam of light. The end of the optical element is subsequently moved transversally (perpendicular) to the beam of light until a position of maximum optical power, as measured through the optical element, is identified. A beam width of the beam of light is measured at that axial location. The movement and measurement sequence is repeated at multiple axial locations relative to the beam of light. Linear regression, or an equivalent approach is used, to predict an axial location relative to the beam of light with the target beam width. The end of the optical element is then moved to the axial location with the target beam width.Type: GrantFiled: July 31, 2002Date of Patent: August 17, 2004Assignee: Agilent Technologies, Inc.Inventors: John Bernard Medberry, Benno Guggenheimer
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Publication number: 20040022498Abstract: Fiber optic alignment methods and apparatus in accordance with the present invention first identify a target beam width incidence on an end of an optical element. The end of the optical element is placed into a beam of light at an axial location relative to the beam of light. The end of the optical element is subsequently moved transversally (perpendicular) to the beam of light until a position of maximum optical power, as measured through the optical element, is identified. A beam width of the beam of light is measured at that axial location. The movement and measurement sequence is repeated at multiple axial locations relative to the beam of light. Linear regression, or an equivalent approach is used, to predict an axial location relative to the beam of light with the target beam width. The end of the optical element is then moved to the axial location with the target beam width.Type: ApplicationFiled: July 31, 2002Publication date: February 5, 2004Inventors: John Bernard Medberry, Benno Guggenheimer
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Publication number: 20030063277Abstract: An optical system for detecting and coupling light to optical devices, and a method for aligning and calibrating the system. The system includes positioning stages and fiber sensors. The fiber sensors are used to detect the positions of calibration pieces and other sensors in a variety of configurations. From these detected positions, any misalignment of the sensors or positioning stages may be calculated and corrected for. The fiber sensors calibrate the system.Type: ApplicationFiled: September 28, 2001Publication date: April 3, 2003Inventors: William P. Kennedy, John Bernard Medberry, David Washburn, Benno Guggenheimer, James D. Adams
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Publication number: 20030042441Abstract: An edge detector with sub-micron accuracy. The edge detector comprises two single mode optical fibers with an optical path between them. One fiber is coupled to a laser light source, and creates a light beam. The other fiber is coupled to an optical power detector. The optical power reaching the optical power detector is determined by how much of the light beam is obscured by an object. Thus the position of the edge of the object may be determined from the optical power measured by the detector. The edge of an object may be positioned automatically according to the optical power measured by the detector.Type: ApplicationFiled: August 22, 2001Publication date: March 6, 2003Inventors: Edward Steketee, John Bernard Medberry, Benno Guggenheimer