Patents by Inventor Benno Muller-Hill

Benno Muller-Hill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Positive selection vector based on the caps gene, pCAPs vector and its use
    Patent number: 5891687
    Abstract: A vector according to the invention with a positive selection possibility for cloning a DNA sequence into a host cell transformed with the vector, wherein the vector contains suitable restriction cleavage sites within a selection gene the functional expression of which is prevented by insertion of the foreign gene is characterized in that it contains a modified cap gene as the selection gene which codes for a CAP protein with modified DNA binding specificity the expression of which is lethal for adenylate-cyclase-positive host cells.
    Type: Grant
    Filed: July 14, 1997
    Date of Patent: April 6, 1999
    Assignee: Boehringer Mannheim GmbH
    Inventors: Daniel Schlieper, Harlad Sobek, Manfred Schmidt, Brigitte von Wilcken-Bergmann, Benno Muller-Hill
  • DNA encoding for the precursor protein of APC polypeptide associated with Alzheimer's disease
    Patent number: 5218100
    Abstract: The present invention relates to the precursor protein of amyloid plaque core (APC) polypeptide, to fragments of the precursor protein and to the diagnostic use of the precursor protein and of the fragments. Furthermore, the invention relates to the DNA coding for the precursor protein, to fragments of this DNA and to the diagnostic use of the DNA and of the fragments.
    Type: Grant
    Filed: January 15, 1988
    Date of Patent: June 8, 1993
    Assignee: Bayer Aktiengesellschaft
    Inventors: Benno Muller-Hill, Jie Kang, Hans-Georg Lemaire, Axel Unterbeck