Abstract: A method and system for analysing gait patterns of a subject by measuring head acceleration in vertical direction. The system comprises an accelerometer mounted on the head of the subject. The analysis includes calculating a signature from the acceleration data, using a Fourier transform, including energy of the first harmonics and comparing the signature with the baseline signature. Baseline signature is a representative of previously stored signatures. The comparison is done in order to monitor changes in the gait signatures over time. The entropy of the signatures may be used to perform the comparison. A self organised map is used to classify the measured gait signals.

Abstract: A humanised antibody capable of binding to the MUC1 mucin antigen comprises a light chain and a heavy chain. The variable region of the light chain (VL) comprising an amino acid sequence which is substantially homologous with the sequence of FIG. 1A and the variable region of the heavy chain (VH) comprising an amino acid sequence which is substantially homologous with the sequence of FIG. 1B. The amino acid residue at position 46 on VL is backmutated to arginine, and the amino acid residue at position 47 on VH is backmutated to leucine. The humanised antibody has use in the diagnosis and/or treatment of cancer.