Patents by Inventor Benoît Darblade

Benoît Darblade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240050582
    Abstract: Conjugates (I), useful for pig feeds, include saccharidic chains X(Fuc?2)Gal?k(Y)TV (II) covalently grafted on a linear protein W, wherein: X is absent, or is Gal?3 or GalNAc?3 and when X is absent, then Y is absent; Y is absent or is Fuc?2 or Fuc?4; T is absent or is ZNAc?3; wherein Z is Glc or Gal; and ? is ? or ?; V is absent or is a mono, or an oligosaccharide; n is an integer equal to 8 or more, k is 3 or 4, and wherein the covalent grafting occurs either between V and the linear protein W, when V is present, or between T and the linear protein W, when T is present and V is absent, or between Gal?k and the linear protein W, when both T and V are absent; and wherein the saccharidic unit covalently bonded to the linear protein may be open and acyclic.
    Type: Application
    Filed: March 7, 2022
    Publication date: February 15, 2024
    Inventors: Eric COX, Ut NGUYEN VAN, Benoit DARBLADE, Ludovic BASTIDE, Silvère BONNET
  • Publication number: 20230000088
    Abstract: The invention concerns the use of alginate oligomers in sequence ?(1-4)Guluronane and/or ?(1-4)Mannuronane having a DP greater than 30, as an active ingredient of biocontrol products in plants, and that may be combined with another molecules such as phytohormones, against cryptogamic diseases of plants, in particular of vine (Vitis vinifera), or to protect other species against aggressors such as pathogenic microbes or insects.
    Type: Application
    Filed: December 18, 2020
    Publication date: January 5, 2023
    Inventors: Benoît POINSSOT, Marie-Claire HELOIR, Xavier DAIRE, Benoît DARBLADE, Christelle LEMAITRE-GUILLIER
  • Patent number: 10758890
    Abstract: The present invention provides a substrate for purifying a biological liquid comprising a solid phase onto which molecules of at least one oligosaccharide that is capable of binding to one or more antibodies are grafted by covalent bonding, said solid phase carrying free aldehyde functions —CHO, a method of producing such a substrate, the use of such a substrate to stabilize the antibody/oligosaccharide bond, as well as a method of purifying a biological liquid in which the biological liquid is brought into contact with at least one substrate of the invention, in a manner such as to obtain the capture of antibodies present in said biological liquid by binding with at least certain of the molecules of oligosaccharide(s) grafted onto the solid phase.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: September 1, 2020
    Assignee: ELICITYL
    Inventors: Ludovic Bastide, Silvère Bonnet, Benoit Darblade, Stéphane Havet, Bernard Mandrand, Mialy Randriantsoa
  • Patent number: 10751698
    Abstract: The present invention concerns a method of purifying a biological liquid comprising antibodies corresponding to whole human or animal blood or to a product obtained from human or animal blood, by bringing a biological liquid into contact with at least one substrate comprising a solid phase onto which molecules of at least one oligosaccharide are grafted by covalent bonding, the molecules of the at least one oligosaccharide being capable of binding to one or more of said antibodies present in said biological liquid, in a manner such as to capture at least a portion of said antibodies present in said biological liquid by binding with at least certain of the molecules of oligosaccharide(s) grafted onto said solid phase, characterized in that said solid phase carries free aldehyde functions —CHO.
    Type: Grant
    Filed: May 3, 2016
    Date of Patent: August 25, 2020
    Assignees: ELICITYL, RESEARCH FOUNDATION FOR MEDICAL DEVICES
    Inventors: Ludovic Bastide, Silvère Bonnet, Benoît Darblade, Stéphane Havet, Bernard Mandrand, Mialy Randriantsoa, Jean-Philippe Zeris
  • Publication number: 20180345250
    Abstract: The present invention concerns a method of purifying a biological liquid comprising antibodies corresponding to whole human or animal blood or to a product obtained from human or animal blood, by bringing a biological liquid into contact with at least one substrate comprising a solid phase onto which molecules of at least one oligosaccharide are grafted by covalent bonding, the molecules of the at least one oligosaccharide being capable of binding to one or more of said antibodies present in said biological liquid, in a manner such as to capture at least a portion of said antibodies present in said biological liquid by binding with at least certain of the molecules of oligosaccharide(s) grafted onto said solid phase, characterized in that said solid phase carries free aldehyde functions —CHO.
    Type: Application
    Filed: May 3, 2016
    Publication date: December 6, 2018
    Inventors: Ludovic BASTIDE, Silvère BONNET, Benoît DARBLADE, Stéphane HAVET, Bernard MANDRAND, Mialy RANDRIANTSOA, Jean-Philippe ZERIS
  • Publication number: 20180345249
    Abstract: The present invention provides a substrate for purifying a biological liquid comprising a solid phase onto which molecules of at least one oligosaccharide that is capable of binding to one or more antibodies are grafted by covalent bonding, said solid phase carrying free aldehyde functions —CHO, a method of producing such a substrate, the use of such a substrate to stabilize the antibody/oligosaccharide bond, as well as a method of purifying a biological liquid in which the biological liquid is brought into contact with at least one substrate of the invention, in a manner such as to obtain the capture of antibodies present in said biological liquid by binding with at least certain of the molecules of oligosaccharide(s) grafted onto the solid phase.
    Type: Application
    Filed: May 3, 2016
    Publication date: December 6, 2018
    Inventors: Ludovic BASTIDE, Silvère BONNET, Benoit DARBLADE, Stéphane HAVET, Bernard MANDRAND, Mialy RANDRIANTSOA
  • Patent number: 9011939
    Abstract: The present invention relates to polysaccharides selected from sulphated arabinogalactans, apiogalacturonans and sulphated heteroglycans intended to be used as a drug for the preventive or curative treatment of an influenza virus, as well as to the pharmaceutical compositions including, in particular in combination with at least one pharmaceutically acceptable carrier: either an extract of Codium fragile, including sulphated arabinogalactans, or an extract of Zostera marina or Lemna minor, including apiogalacturonans, or an extract of Caulerpa racemosa, including sulphated heteroglycans.
    Type: Grant
    Filed: January 3, 2012
    Date of Patent: April 21, 2015
    Assignees: Elicityl, Centre National de la Recherche Scientifique, Insititut National de la Sante et de la Recherche Medicale—I.N.S.E.R.M., Commissariat a l'Energie Atomique et aux Energies Alternatives (CEA)
    Inventors: Bruno Lina, Olivier Ferraris, Ho Hong Hai Vo, François-Loïc Cosset, Judit Szecsi, Alain Heyraud, Hugues Lortat-Jacob, Julia Bartoli, Rabia Sadir, Thierry Livache, Benoît Darblade, Stéphane Havet, Silvère Bonnet
  • Publication number: 20140023675
    Abstract: The present invention relates to polysaccharides selected from sulphated arabinogalactans, apiogalacturonans and sulphated heteroglycans intended to be used as a drug for the preventive or curative treatment of an influenza virus, as well as to the pharmaceutical compositions including, in particular in combination with at least one pharmaceutically acceptable carrier: either an extract of Codium fragile, including sulphated arabinogalactans, or an extract of Zostera marina or Lemna minor, including apiogalacturonans, or an extract of Caulerpa racemosa, including sulphated heteroglycans.
    Type: Application
    Filed: January 3, 2012
    Publication date: January 23, 2014
    Applicants: Elicityl, Commissariat A L'Energie Atomique Et Aux Energies Alternatives (CEA), Institut National De La Sante Et De La Recherche Medicale - I.N.S.E.R.M., Centre National De La Recherche Scientifique
    Inventors: Bruno Lina, Olivier Ferraris, Ho Hong Hai Vo, Francois-Loic Cosset, Judit Szecsi, Alain Heyraud, Hugues Lortat-Jacob, Julia Bartoli, Rabia Sadir, Thierry Livache, Benoit Darblade, Stephane Havet, Silvére Bonnet