Patents by Inventor Benoît Kenda

Benoît Kenda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRM1 inhibitors for treating epilepsy
    Patent number: 11602530
    Abstract: The invention generally relates to the use of nuclear transport modulators, e.g., CRM1 inhibitors, of Formula (I) for treating epilepsy in a subject. Subjects can have unprovoked seizures without prior warning that affect one or both hemispheres of the brain. The disclosed methods can reduce the severity and occurrence of these unprovoked epileptic seizures and can result in resolution of epilepsy. The method comprises administering to the subject an effective amount of a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: March 14, 2023
    Assignee: BIOGEN MA INC.
    Inventors: Sharon Tamir, Margaret Lee, Marc De Ryck, Rafal M. Kaminski, Karine Leclercq, Benoit Kenda
  • CRM1 INHIBITORS FOR TREATING EPILEPSY
    Publication number: 20190374527
    Abstract: The invention generally relates to the use of nuclear transport modulators, e.g., CRM1 inhibitors, of Formula (I) for treating epilepsy in a subject. Subjects can have unprovoked seizures without prior warning that affect one or both hemispheres of the brain. The disclosed methods can reduce the severity and occurrence of these unprovoked epileptic seizures and can result in resolution of epilepsy. The method comprises administering to the subject an effective amount of a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 28, 2017
    Publication date: December 12, 2019
    Inventors: Sharon Tamir, Margaret Lee, Marc De Ryck, Rafal M. Kaminski, Karine Leclercq, Benoit Kenda
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8586623
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: November 19, 2013
    Assignee: UCB Pharma, S.A.
    Inventors: Benoit Kenda, Yannick Quesnel, Ali Ates, Philippe Michel, Laurent Turet, Joel Mercier
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8518943
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: August 27, 2013
    Assignee: UCB Pharma, S.A.
    Inventors: Benoit Kenda, Yannick Quesnel, Ali Ates, Philippe Michel, Laurent Turet, Joel Mercier
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8492416
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: July 23, 2013
    Assignee: UCB Pharma, S.A.
    Inventors: Benoît Kenda, Patrick Pasau, Bénédicte Lallemand
  • Benzoxazolone derivatives, processes for preparing them and their uses
    Patent number: 8293775
    Abstract: The present invention relates to benzoxazolone derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals, in the treatment of movement disorders, in particular in Parkinson's disease.
    Type: Grant
    Filed: May 24, 2005
    Date of Patent: October 23, 2012
    Assignee: UCB Pharma, S.A.
    Inventors: Jean-Philippe Starck, Benoît Kenda
  • 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses
    Publication number: 20120214815
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: April 6, 2012
    Publication date: August 23, 2012
    Applicant: UCB Pharma, S.A.
    Inventors: Benoît KENDA, Yannick QUESNEL, Ali ATES, Philippe MICHEL, Laurent TURET, Joël MERCIER
  • 2-Oxo-1-Pyrrolidine Derivatives, Processes for Preparing Them and Their Uses
    Publication number: 20120196866
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: April 6, 2012
    Publication date: August 2, 2012
    Applicant: UCB PHARMA, S.A.
    Inventors: Benoît Kenda, Yannick Quesnel, Ali Ates, Philippe Michel, Laurent Turet, Joël Mercier
  • Methods for Enhancing the Cognitive Function
    Publication number: 20120171125
    Abstract: A compound having an affinity to a SV2 protein for the treatment of a condition associated with enhancement or improvement of the cognitive ability or to counteract cognitive decline of a mammal. For example, a compound which is covered by formula (I) R1 is an halogen atom, preferably, a chlorine or a fluorine atom; n is equal to 1, 2 or 3; and R2 is cyano.
    Type: Application
    Filed: August 4, 2010
    Publication date: July 5, 2012
    Applicant: UCB PHARMA, S.A.
    Inventors: Benoît Kenda, Alain Matagne
  • 2-oxo-1-pyrrolidine derivatives
    Patent number: 8183241
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: May 22, 2012
    Assignee: UCB Pharma, S.A.
    Inventors: Benoît Kenda, Yannick Quesnel, Ali Ates, Philippe Michel, Laurent Turet, Joël Mercier
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8178533
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: May 15, 2012
    Assignee: UCB Pharma, S.A.
    Inventors: Benoît Kenda, Yannick Quesnel, Ali Ates, Philippe Michel, Laurent Turet, Joël Mercier
  • 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES
    Publication number: 20120035239
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: August 31, 2011
    Publication date: February 9, 2012
    Inventors: Benoît KENDA, Patrick PASAU, Bénédicte LALLEMAND
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8034958
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: October 11, 2011
    Assignee: UOB Pharma, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • Indolone-acetamide derivatives, processes for preparing them and their uses
    Patent number: 7964593
    Abstract: The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: June 21, 2011
    Assignee: UCB Pharma, S.A.
    Inventors: Jean-Philippe Starck, Benoit Kenda
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20100222576
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: February 17, 2010
    Publication date: September 2, 2010
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • New Heterocyclic Derivatives Useful For The Treatment of CNS Disorders
    Publication number: 20100222326
    Abstract: The present invention relates to new compounds, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: April 24, 2008
    Publication date: September 2, 2010
    Applicant: UCB PHARMA, S.A.
    Inventors: Benoit Kenda, Laurent Turet, Yannick Quesnel, Philippe Michel, Ali Ates
  • Imidazole derivatives, processes for preparing them and their uses
    Patent number: 7763644
    Abstract: The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: June 11, 2007
    Date of Patent: July 27, 2010
    Assignee: UCB Pharma, S.A.
    Inventors: Benoît Kenda, Philippe Michel, Yannick Quesnel
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 7692028
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: April 6, 2010
    Assignee: UCB Pharma, S.A.
    Inventors: Edmond Differding, Benoît Kenda, Bénédicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • Indolone-Acetamide Derivatives, Processes for Preparing Them and Their Uses
    Publication number: 20100069375
    Abstract: The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion.
    Type: Application
    Filed: November 20, 2009
    Publication date: March 18, 2010
    Applicant: UCB PHARMA, S.A.
    Inventors: Jean-Philippe Starck, Benoit Kenda
  • Indolone-acetamide derivatives, processes for preparing them and their uses
    Patent number: 7645887
    Abstract: The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: January 12, 2010
    Assignee: UCB Pharma, S.A.
    Inventors: Jean-Philippe Starck, Benoît Kenda