Patents by Inventor Benoit Crousse

Benoit Crousse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIMERIC DERIVATIVES OF ARTEMISININ AND APPLICATION IN ANTI-CANCER THERAPY
    Publication number: 20110152289
    Abstract: The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I) below: Formula (I) and the pharmaceutically acceptable salts thereof, and also to the preparation method thereof and to the uses thereof, especially in the treatment of cancer.
    Type: Application
    Filed: July 29, 2009
    Publication date: June 23, 2011
    Applicants: PIERRE FABRE MEDICAMENT, UNIVERSITE PARIS-SUD
    Inventors: Jean-Pierre Begue, Daniele Bonnet-Delpon, Benoit Crousse, Anais Fournial, Celine Mordant, Jacques Fahy
  • DERIVATIVES OF ARTEMISININ, AND THEIR USES IN THE TREATMENT OF MALARIA
    Publication number: 20080287433
    Abstract: A new artemisinin derivatives, of following general formula (I): In which: a and b are a single or a double bond, n1 and n2 are 0 or 1, R1 is a fluoroalkyl group or a fluoroaryl group, R2 is a hydrogen atom, or a halogen atom, or a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R3 is a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R4 is H or OH. The invention also relates to the process by which they are obtained, and their uses in pharmaceutical compositions intended for the treatment of malaria.
    Type: Application
    Filed: July 9, 2008
    Publication date: November 20, 2008
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Pierre Begue, Daniele Bonnet-Delpon, Benoit Crousse, Michele Ourevitch, Fatima Chorki, Fabienne Grellepois, Guillaume Magueur
  • Aminated compounds bearing at least an allyl and a difluoromethyl and method used for synthesis thereof
    Publication number: 20060079719
    Abstract: The invention relates to aminated compounds bearing at least an allyl and a difluoromethyl and a method used for synthesis thereof. Said compounds comprise at least one carbon bearing: an amine function, an allyl or propargyl radical, a difluoromethylene group, and a hydrogen or a hydrocarbon radical, advantageously selected among those which are electron donors or hardly electroattractive (; 0. 1). The invention is useful for synthesis of fluorinated compounds.
    Type: Application
    Filed: April 15, 2003
    Publication date: April 13, 2006
    Inventors: Daniele Bonnet-Delpon, Jean-Pierre Begue, Julien Legros, Benoit Crousse, Franck Meyer
  • Novel artemisinine derivatives, and uses thereof for treating malaria
    Publication number: 20050038024
    Abstract: A new artemisinin derivatives, of following general formula (I): In which: a and b represent a single or a double bond, n1 and n2 represent 0 or 1, R1 represents a fluoroalkyl group or a fluoroaryl group, R2 represents a hydrogen atom, or a halogen atom, or a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R3 represents a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R4 represents H or OH. The invention also relates to the process by which they are obtained, and their uses in pharmaceutical compositions intended for the treatment of malaria.
    Type: Application
    Filed: October 25, 2002
    Publication date: February 17, 2005
    Inventors: Jean-Pierre Begue, Daniele Bonnet-Delpon, Benoit Crousse, Michele Ourevitch, Fatima Chorki, Fabienne Grellepois, Guillaume Magueur