Patents by Inventor Benoit Kenda

Benoit Kenda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRM1 inhibitors for treating epilepsy
    Patent number: 11602530
    Abstract: The invention generally relates to the use of nuclear transport modulators, e.g., CRM1 inhibitors, of Formula (I) for treating epilepsy in a subject. Subjects can have unprovoked seizures without prior warning that affect one or both hemispheres of the brain. The disclosed methods can reduce the severity and occurrence of these unprovoked epileptic seizures and can result in resolution of epilepsy. The method comprises administering to the subject an effective amount of a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: March 14, 2023
    Assignee: BIOGEN MA INC.
    Inventors: Sharon Tamir, Margaret Lee, Marc De Ryck, Rafal M. Kaminski, Karine Leclercq, Benoit Kenda
  • CRM1 INHIBITORS FOR TREATING EPILEPSY
    Publication number: 20190374527
    Abstract: The invention generally relates to the use of nuclear transport modulators, e.g., CRM1 inhibitors, of Formula (I) for treating epilepsy in a subject. Subjects can have unprovoked seizures without prior warning that affect one or both hemispheres of the brain. The disclosed methods can reduce the severity and occurrence of these unprovoked epileptic seizures and can result in resolution of epilepsy. The method comprises administering to the subject an effective amount of a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: November 28, 2017
    Publication date: December 12, 2019
    Inventors: Sharon Tamir, Margaret Lee, Marc De Ryck, Rafal M. Kaminski, Karine Leclercq, Benoit Kenda
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8586623
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: November 19, 2013
    Assignee: UCB Pharma, S.A.
    Inventors: Benoit Kenda, Yannick Quesnel, Ali Ates, Philippe Michel, Laurent Turet, Joel Mercier
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Patent number: 8518943
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: August 27, 2013
    Assignee: UCB Pharma, S.A.
    Inventors: Benoit Kenda, Yannick Quesnel, Ali Ates, Philippe Michel, Laurent Turet, Joel Mercier
  • Indolone-acetamide derivatives, processes for preparing them and their uses
    Patent number: 7964593
    Abstract: The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: June 21, 2011
    Assignee: UCB Pharma, S.A.
    Inventors: Jean-Philippe Starck, Benoit Kenda
  • New Heterocyclic Derivatives Useful For The Treatment of CNS Disorders
    Publication number: 20100222326
    Abstract: The present invention relates to new compounds, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: April 24, 2008
    Publication date: September 2, 2010
    Applicant: UCB PHARMA, S.A.
    Inventors: Benoit Kenda, Laurent Turet, Yannick Quesnel, Philippe Michel, Ali Ates
  • Indolone-Acetamide Derivatives, Processes for Preparing Them and Their Uses
    Publication number: 20100069375
    Abstract: The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion.
    Type: Application
    Filed: November 20, 2009
    Publication date: March 18, 2010
    Applicant: UCB PHARMA, S.A.
    Inventors: Jean-Philippe Starck, Benoit Kenda
  • 2-OXO-1-PYRROLIDINE DERIVATIVES
    Publication number: 20090156607
    Abstract: The present invention concerns 2-oxo-1-pyrrolidine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: May 31, 2006
    Publication date: June 18, 2009
    Applicant: UCB, S.A.
    Inventors: Benoit Kenda, Yannick Quesnel, Ali Ates, Philippe Michel, Laurent Turet, Joel Mercier
  • Xanthine Derivatives, Processes For Preparing Them And Their Uses
    Publication number: 20090018148
    Abstract: The present invention concerns xanthine derivatives, having formula (I), processes for preparing them, pharmaccutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: November 30, 2006
    Publication date: January 15, 2009
    Applicant: UCB PHARMA, S.A.
    Inventors: Florence Moureau, Benoit Kenda, Frank Driessens, Luc Quere
  • Indolone Derivatives, Processes For Preparing Them And Their Uses
    Publication number: 20090012147
    Abstract: The present invention relates to indolone derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: July 14, 2005
    Publication date: January 8, 2009
    Applicant: UCB PHARMA, S.A.
    Inventors: Benoit Kenda, Jean-Philippe Starck
  • 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20080097109
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: December 13, 2007
    Publication date: April 24, 2008
    Inventors: Edmon Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrick Talaga
  • Imidazole derivatives, processes for preparing them and their uses
    Publication number: 20080081832
    Abstract: The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: June 11, 2007
    Publication date: April 3, 2008
    Inventors: Benoit Kenda, Philippe Michel, Yannick Quesnel
  • Benzoxazolone Derivatives, Processes For Preparing Them And Their Uses
    Publication number: 20070299118
    Abstract: The present invention relates to benzoxazolone derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals, in the treatment of movement disorders, in particular in Parkinson's disease.
    Type: Application
    Filed: May 24, 2005
    Publication date: December 27, 2007
    Applicant: UCB, S.A.
    Inventors: Jean-Philippe Starck, Benoit Kenda
  • Imidazole derivatives, processes for preparing them and their uses
    Patent number: 7244747
    Abstract: The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: July 17, 2007
    Assignee: UCB, S.A.
    Inventors: Benoit Kenda, Philippe Michel, Yannick Quesnel
  • Indolone-acetamide derivatives, processes for preparing them and their uses
    Publication number: 20070043038
    Abstract: The present invention relates to indolone-acetamide derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as for the treatment of epilepsy, epileptogenesis, seizure disorders and convulsion.
    Type: Application
    Filed: March 16, 2004
    Publication date: February 22, 2007
    Applicant: UCB, S.A.
    Inventors: Jean-Philippe Starck, Benoit Kenda
  • 2-Oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders
    Publication number: 20060258704
    Abstract: This invention relates to new 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives of formula (1) having anticonvulsant activity which are useful as therapeutic agents for the treatment or prevention of epilepsy and other neurological disorders. The invention also concerns processes for preparing these derivatives and novel intermediates used in the preparation of these derivatives.
    Type: Application
    Filed: June 15, 2006
    Publication date: November 16, 2006
    Inventors: Philippe Michel, Benoit Kenda
  • N-alkylated GABA compounds, processes for their preparation and their use as medicaments
    Patent number: 7112612
    Abstract: The present invention relates to N-alkylated GABA (Gamma-aminobutyric acid) compounds, to processes for their preparation, to their use in therapy and to pharmaceutical compositions containing them. More particularly these compounds are useful for treatment of disorders of the central and/or peripheral nervous system. Of particular interest is their potent anticonvulsant activity.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: September 26, 2006
    Assignee: UCB S.A.
    Inventors: Benoit Kenda, Philippe Michel, Luc Quere
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20050171187
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 4, 2005
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
    Publication number: 20050171188
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.
    Type: Application
    Filed: January 27, 2005
    Publication date: August 4, 2005
    Inventors: Edmond Differding, Benoit Kenda, Benedicte Lallemand, Alain Matagne, Philippe Michel, Patrick Pasau, Patrice Talaga
  • Imidazole derivatives, processes for preparing them and their uses
    Publication number: 20050137241
    Abstract: The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: November 30, 2004
    Publication date: June 23, 2005
    Inventors: Benoit Kenda, Philippe Michel, Yannick Quesnel