Patents by Inventor Benoit Mothes

Benoit Mothes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FULL FLOW-THROUGH PROCESS FOR PURIFYING RECOMBINANT PROTEINS
    Publication number: 20210009634
    Abstract: The present invention concerns a method for purifying a protein comprising in a continuous mode: one filtration step involving the use of at least one chelating agent, an exchanging step involving the use of at least one diafiltration membrane, and a polishing step involving the use of a combination of membrane adsorbers, wherein two membrane adsorbers of said combination are orthogonal in terms of mechanism of action.
    Type: Application
    Filed: March 27, 2019
    Publication date: January 14, 2021
    Inventors: Didier DUTHE, Céline HEMET, Benoit MOTHES, Jérome PEZZINI
  • Continuous multistep process for purifying antibodies
    Patent number: 10793622
    Abstract: The invention provides a three-step chromatography process for small and large-scale purification of proteins, specifically monoclonal antibodies, using only four buffer solutions made from a mother solution.
    Type: Grant
    Filed: May 6, 2014
    Date of Patent: October 6, 2020
    Assignee: SANOFI
    Inventors: Didier Duthe, Celine Hemet, Laure Landric-Burtin, Benoit Mothes
  • PROTEIN PURIFICATION USING BIS-TRIS BUFFER
    Publication number: 20190135942
    Abstract: The invention provides a two-step chromatography process for small and large-scale purification of proteins, specifically monoclonal antibodies, using only four buffer solutions made from a mother solution.
    Type: Application
    Filed: October 4, 2018
    Publication date: May 9, 2019
    Inventors: Didier DUTHE, Laure LANDRIC-BURTIN, Benoit MOTHES
  • Protein purification using bis-tris buffer
    Patent number: 10131714
    Abstract: The invention provides a two-step chromatography process for small and large-scale purification of proteins, specifically monoclonal antibodies, using only four buffer solutions made from a mother solution.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: November 20, 2018
    Assignee: SANOFI
    Inventors: Didier Duthe, Laure Landric-Burtin, Benoit Mothes
  • CONTINUOUS MULTISTEP PROCESS FOR PURIFYING ANTIBODIES
    Publication number: 20160083454
    Abstract: The invention provides a three-step chromatography process for small and large-scale purification of proteins, specifically monoclonal antibodies, using only four buffer solutions made from a mother solution.
    Type: Application
    Filed: May 6, 2014
    Publication date: March 24, 2016
    Inventors: Didier DUTHE, Celine HEMET, Laure LANDRIC-BURTIN, Benoit MOTHES
  • PROTEIN PURIFICATION USING BIS-TRIS BUFFER
    Publication number: 20140323698
    Abstract: The invention provides a two-step chromatography process for small and large-scale purification of proteins, specifically monoclonal antibodies, using only four buffer solutions made from a mother solution.
    Type: Application
    Filed: May 23, 2012
    Publication date: October 30, 2014
    Inventors: Didier Duthe, Laure Landric-Burtin, Benoit Mothes