Abstract: The invention provides new benzimidazole compositions, comprising: (a) a core containing said benzimidazole active ingredient; (b) an intermediate layer; and (c) an enteric layer; said core being substantially free of binder. The invention also provides a process for manufacturing the composition of the invention.

Abstract: The invention provides new benzimidazole compositions, comprising: (a) a core containing said benzimidazole active ingredient; (b) an intermediate layer; and (c) an enteric layer; said core being substantially free of binder. The invention also provides a process for manufacturing the composition of the invention.

Abstract: A process for the manufacture of compositions containing niacin, the process including a first compaction step of niacin or a pharmaceutically acceptable salt thereof, then a second compaction step of a dry blend comprising niacin and microcrystalline cellulose and a further compression step into tablets. Stable tablet compositions including niacin are capable of extended release of niacin.

Abstract: The manufacture of compositions containing montelukast and to stable tablet compositions resulting thereof are disclosed, which include a first compaction step of a dry blend including, montelukast or a pharmaceutically acceptable salt thereof, and microcrystalline cellulose, and a further compression step into tablets.

Abstract: The invention provides new benzimidazole compositions, comprising: (a) a core containing said benzimidazole active ingredient; (b) an intermediate layer; and (c) an enteric layer; said core being substantially free of binder. The invention also provides a process for manufacturing the composition of the invention.

Abstract: A communication device for an electromagnetic telemetry system for use in a well is adapted to be attached to a conductive pipe of the well and includes at least one transmitter unit for emitting a modulated electrical current in the pipe and at least one receiver unit for receiving the modulated electrical current transmitted in the pipe, the transmitter unit and the receiver unit each comprising an antenna with a magnetic core and a winding around the magnetic core, wherein the antenna is oriented such that the magnetic moment of the winding is tangential to the cross-section of the pipe for respectively emitting and receiving the modulated electrical current.

Abstract: A subsurface formation monitoring system and method is described. The system includes a conductive piping structure positionable within a borehole extending into a subsurface formation. The conductive piping structure is electrically decoupled from a production tubing by an insulating packer. The system also includes a downhole installed conductive casing sub that has one or more sensors. The conductive casing sub is electrically coupled to the conductive piping structure. The system further includes a surface installed power and communication module that has an alternate current generator. The power and communication module is electrically coupled to the conductive piping structure via a downhole intermediate module. The alternate current generator can inject a current signal that flows downhole to the conductive casing sub and then returns with sensor measurements to the surface power and communication module via a grounded return electrode that is coupled to the subsurface formation.

Abstract: A subsurface formation monitoring system and method is provided. The system comprises a conductive piping structure having a conductive tubing, a surface installed power and communication module coupled to the conductive piping structure, and a downhole installed conductive tubing sub.

Abstract: A subsurface formation monitoring system comprises a conductive piping positioned within a borehole extending into the formation, a surface installed power and communication module, a downhole installed conductive casing or tubing sub comprising sensor(s) mounted on the sub, a data communication module for wireless communication of sensor measurements to the surface module, and a battery for providing power to the data communication module and the sensor. The surface module is coupled to the conductive piping and to a grounded return electrode coupled to the formation, and comprises an alternate current generator that defines an ingoing signal path along the conductive piping and sub, the ingoing signal flowing from the surface module to the sub and transmitting power from the generator to the sub. A return signal comprising sensor measurements is transmitted through a return signal path flowing from the sub to the surface module.

Abstract: The present invention relates to an improved statin or salt thereof composition, especially an atorvastatin composition, which exhibits enhanced dissolution properties in acidic media. It comprises a statin active ingredient and an aminoalkyl methacrylate copolymer dispersed therein, such as dimethyl aminoethyl methacrylate. The invention also relates to a process for preparing the improved composition and to methods of using it for the treatment of dyslipidemia.

Abstract: The invention provides a sartan or salt thereof composition having a dissolution in acetate buffer at pH 4.

Abstract: The invention provides a xetine or salt thereof composition having a dissolution in a phosphate buffer at pH 6.8, using USP basket 10 Mesh at 75 rpm, of at least 15% at 60 minutes, of at least 40% at 120 minutes, of at least 70% at 300 minutes.

Abstract: A subsurface formation monitoring system comprises: a conductive piping structure 2 comprising either a conductive casing or a non conductive casing fitted with a conductive tubing, the conductive piping being positioned within a borehole BH extending into the subsurface formation GF, a surface installed power and communication module 3, and a downhole installed conductive casing or tubing sub 4A, 4B, 4C comprising at least one sensor 5, 15 mounted on the sub, a data communication module 6 for wireless communication of the sensor measurements to the surface installed power and communication module, and a powering means 7 for providing power to the data communication module 6 and the sensor 5, 15.

Abstract: An electric motor for use in a borehole tool, comprising: a housing; a plurality of stator windings spaced along the inside of the housing; an output shaft located in the housing; a plurality of rotors disposed on the output shaft and aligned with the stators so as to define a plurality of motor sub-units; and separate power supplies and control systems for each motor sub-unit; wherein each motor sub-unit is separately controllable by means of its associated power supply and control system. The output shaft can comprise a single shaft with the rotors disposed thereon or a plurality of sub-shafts connected end to end with each rotor can be disposed on an associated sub-shaft. The sub-shafts can connected by means of articulated connections, and the housing can be articulated in the region of the connections.

Abstract: The invention relates to a novel benzimidazole formulation and to a process for its production. The benzimidazole formulation comprises a layer comprising the benzimidazole compound together with an acidic reacting compound.

Abstract: The invention provides an extended release pharmaceutical tablet containing: (i) a core comprising by weight, based on the core weight, about 70% to about 99% metformin and pharmaceutically acceptable excipients; and (ii) a coating surrounding said core, wherein said coating is permeable to metformin. The extended release tablets of the invention exhibit a dissolution profile such that after about 2 hours, from about 7% to about 60% of the metformin is released; after about 4 hours, from about 15% to about 90% of the metformin is released; after about 8 hours, from about 50% to about 100% of the metformin is released; after about 12 hours, more than about 75% of the metformin is released.

Abstract: The invention relates to a novel benzimidazole formulation and to a process for its production. The benzimidazole formulation comprises a layer comprising the benzimidazole compound together with an acidic reacting compound.