Patents by Inventor Benoit Smagghe

Benoit Smagghe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-MUC1* ANTIBODY DRUG COMPLEXES AND USES THEREOF
    Publication number: 20250121088
    Abstract: Described herein are anti-MUC1* antibodies or antibody fragments and antibody drug complex (ADC) comprising an anti-MUC1* antibody conjugated via a linker to a toxin. The present disclosure also provides compositions comprising the antibodies and antibody drug complexes and methods for treating diseases and disorders such as cancer.
    Type: Application
    Filed: October 9, 2024
    Publication date: April 17, 2025
    Inventors: Cynthia Bamdad, Benoit Smagghe, Scott Moe, Thomas Jeon
  • ANTI-VARIABLE MUC1* ANTIBODIES AND USES THEREOF
    Publication number: 20250114471
    Abstract: Described herein are methods and compositions for the targeted delivery of therapeutic agents and multispecific antibodies or antibody fragments comprising a binding domain to MUC1* and a binding domain to CD3. The present disclosure also provides compositions comprising antibodies and methods for treating diseases and disorders such as cancer.
    Type: Application
    Filed: April 11, 2023
    Publication date: April 10, 2025
    Inventors: Cynthia Bamdad, Benoit Smagghe, Scott Moe, Thomas Jeon
  • HUMANIZED ANTI-MUC1* ANTIBODIES
    Publication number: 20250026853
    Abstract: The present application discloses humanized antibodies and antibody like proteins and fragments thereof.
    Type: Application
    Filed: April 24, 2024
    Publication date: January 23, 2025
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • ANTI-CANCER PEPTIDE
    Publication number: 20250011469
    Abstract: The present application discloses anti-NME antibodies and their use in treating or preventing diseases.
    Type: Application
    Filed: April 12, 2022
    Publication date: January 9, 2025
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • CHIMERIC ANTIGEN RECEPTOR COMPOSITIONS AND METHODS FOR TREATING MUC1* DISEASES
    Publication number: 20240424025
    Abstract: Disclosed herein are chimeric antigen receptors (CARs) that target MUC1*. In some embodiments, the CARs have been optimized to reduce T cell exhaustion.
    Type: Application
    Filed: September 3, 2024
    Publication date: December 26, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • ANTI-NME ANTIBODY AND METHOD OF TREATING CANCER OR CANCER METASTASIS
    Publication number: 20240392038
    Abstract: The present application discloses anti-NME antibodies and their use in treating or preventing diseases.
    Type: Application
    Filed: June 3, 2024
    Publication date: November 28, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Chimeric antigen receptor compositions and methods for treating MUC1* diseases
    Patent number: 12115192
    Abstract: Disclosed herein are chimeric antigen receptors (CARs) that target MUC1*. In some embodiments, the CARs have been optimized to reduce T cell exhaustion.
    Type: Grant
    Filed: February 1, 2024
    Date of Patent: October 15, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • NUCLEIC ACID ENCODING GENETICALLY ENGINEERED GROWTH FACTOR VARIANTS
    Publication number: 20240294590
    Abstract: The present application discloses a recombinantly made protein construct that preferentially forms multimers.
    Type: Application
    Filed: April 19, 2024
    Publication date: September 5, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • NME INHIBITORS AND METHODS OF USING NME INHIBITORS
    Publication number: 20240277803
    Abstract: The present application discloses inhibitors of NME family of proteins.
    Type: Application
    Filed: February 12, 2024
    Publication date: August 22, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • CHIMERIC ANTIGEN RECEPTOR COMPOSITIONS AND METHODS FOR TREATING MUC1* DISEASES
    Publication number: 20240261406
    Abstract: Disclosed herein are chimeric antigen receptors (CARs) that target MUC1*. In some embodiments, the CARs have been optimized to reduce T cell exhaustion.
    Type: Application
    Filed: January 9, 2024
    Publication date: August 8, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • CHIMERIC ANTIGEN RECEPTOR COMPOSITIONS AND METHODS FOR TREATING MUC1* DISEASES
    Publication number: 20240261331
    Abstract: Disclosed herein are chimeric antigen receptors (CARs) that target MUC1*. In some embodiments, the CARs have been optimized to reduce T cell exhaustion.
    Type: Application
    Filed: February 1, 2024
    Publication date: August 8, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Anti-NME antibody and method of treating cancer or cancer metastasis
    Patent number: 12049514
    Abstract: The present application discloses anti-NME antibodies and their use in treating or preventing diseases.
    Type: Grant
    Filed: June 8, 2021
    Date of Patent: July 30, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • MEDIA FOR STEM CELL PROLIFERATION AND INDUCTION
    Publication number: 20240247229
    Abstract: The present application discloses a cell culture media for growth, maintenance and induction of reversion to a less mature state of a cell comprising a MUC1* activating ligand.
    Type: Application
    Filed: January 3, 2024
    Publication date: July 25, 2024
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Anti-NME antibody and method of treating cancer or cancer metastasis
    Patent number: 12037413
    Abstract: The present application discloses anti-NME antibodies and their use in treating or preventing diseases.
    Type: Grant
    Filed: August 3, 2021
    Date of Patent: July 16, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Humanized anti-MUC1* antibodies
    Patent number: 12006371
    Abstract: The present application discloses humanized antibodies and antibody like proteins and fragments thereof.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: June 11, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Media for stem cell proliferation and induction
    Patent number: 11976295
    Abstract: The present application discloses a cell culture media for growth, maintenance and induction of reversion to a less mature state of a cell comprising a MUC1* activating ligand.
    Type: Grant
    Filed: January 12, 2023
    Date of Patent: May 7, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Humanized anti-MUC1* antibodies
    Patent number: 11897967
    Abstract: The present application discloses humanized antibodies and antibody like proteins and fragments thereof.
    Type: Grant
    Filed: August 4, 2022
    Date of Patent: February 13, 2024
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • MEDIA FOR STEM CELL PROLIFERATION AND INDUCTION
    Publication number: 20230287338
    Abstract: The present application discloses a cell culture media for growth, maintenance and induction of reversion to a less mature state of a cell comprising a MUC1* activating ligand.
    Type: Application
    Filed: January 12, 2023
    Publication date: September 14, 2023
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • HUMANIZED ANTI-MUC1* ANTIBODIES
    Publication number: 20230279142
    Abstract: The present application discloses humanized antibodies and antibody like proteins and fragments thereof.
    Type: Application
    Filed: August 4, 2022
    Publication date: September 7, 2023
    Inventors: Cynthia Bamdad, Benoit Smagghe
  • Humanized anti-MUC1* antibodies
    Patent number: 11746159
    Abstract: The present application discloses humanized antibodies and antibody like proteins and fragments thereof.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: September 5, 2023
    Assignee: MINERVA BIOTECHNOLOGIES CORPORATION
    Inventors: Cynthia Bamdad, Benoit Smagghe