Patents by Inventor Bensheng Ju

Bensheng Ju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220256819
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Application
    Filed: February 25, 2022
    Publication date: August 18, 2022
    Applicant: National University of Singapore
    Inventors: Zhiyuan GONG, Jiangyan HE, Bensheng JU, Toong Jin LAM, Yanfei XU, Tie YAN
  • Patent number: 11259509
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: March 1, 2022
    Assignee: National University of Singapore
    Inventors: Zhiyuan Gong, Jiangyan He, Bensheng Ju, Toong Jin Lam, Yanfei Xu, Tie Yan
  • Publication number: 20180064074
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Application
    Filed: August 11, 2017
    Publication date: March 8, 2018
    Applicant: National University of Singapore
    Inventors: Zhiyuan GONG, Jiangyan HE, Bensheng JU, Toong Jin LAM, Yanfei XU, Tie YAN
  • Patent number: 9763430
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: September 19, 2017
    Assignee: National University of Singapore
    Inventors: Zhiyuan Gong, Jiangyan He, Bensheng Ju, Toong Jin Lam, Yanfei Xu, Tie Yan
  • Publication number: 20140007265
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Application
    Filed: January 10, 2013
    Publication date: January 2, 2014
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Zhiyuan GONG, Jiangyan HE, Bensheng JU, Toong Jin LAM, Yanfei XU, Tie YAN
  • Patent number: 8378169
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: February 19, 2013
    Assignee: National University of Singapore
    Inventors: Zhiyuan Gong, Jiangyan He, Bensheng Ju, Toong Jin Lam, Yanfei Xu, Tie Yan
  • Publication number: 20120167241
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Application
    Filed: December 22, 2011
    Publication date: June 28, 2012
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Zhiyuan GONG, Jiangyan HE, Bensheng JU, Toon Jin LAM, Yanfei XU, Tie YAN
  • Patent number: 8153858
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Grant
    Filed: May 15, 2007
    Date of Patent: April 10, 2012
    Assignee: National University of Singapore
    Inventors: Zhiyuan Gong, Jiangyan He, Bensheng Ju, Toong Jin Lam, Yanfei Xu, Tie Yan
  • Patent number: 7834239
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: November 16, 2010
    Assignee: The National University of Singapore
    Inventors: Zhiyuan Gong, Jiangyan He, Bensheng Ju, Toong Jin Lam, Yanfei Xu, Tie Yan
  • Publication number: 20080052787
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Application
    Filed: May 15, 2007
    Publication date: February 28, 2008
    Inventors: Zhiyuan Gong, Jiangyan He, Bensheng Ju, Toong Lam, Yanfei Xu, Tie Yan
  • Patent number: 7135613
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed, respectively, were isolated and ligated to the 5? end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultra-violet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patters, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Grant
    Filed: July 16, 1999
    Date of Patent: November 14, 2006
    Assignee: The National University of Singapore
    Inventors: Zhiyuan Gong, Jiangyan He, Bensheng Ju, Toong Jin Lam, Yanfei Xu, Tie Yan
  • Publication number: 20040143864
    Abstract: Four zebrafish gene promoters, which are skin specific, muscle specific, skeletal muscle specific and ubiquitously expressed respectively, were isolated and ligated to the 5′ end of the EGFP gene. When the resulting chimeric gene constructs were introduced into zebrafish, the transgenic zebrafish emit green fluorescence under a blue light or ultraviolet light according to the specificity of the promoters used. Thus, new varieties of ornamental fish of different fluorescence patterns, e.g., skin fluorescence, muscle fluorescence, skeletal muscle-specific and/or ubiquitous fluorescence, are developed.
    Type: Application
    Filed: October 21, 2003
    Publication date: July 22, 2004
    Applicant: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Zhiyuan Gong, Jiangyan He, Bensheng Ju, Toong Jin Lam, Yanfei Xu, Tie Yan