Patents by Inventor Bent Erling Nielsen

Bent Erling Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6932893
    Abstract: The present invention relates to a high through-put system for determining and/or monitoring electrophysiological properties of ion channels of ion channel-containing membranes, typically lipid membrane-containing structures such as cells. In particular, the invention provides a substrate which provides means for automatically positioning cells at measuring sites using electroosmotic flow in canals formed on or in the substrate. The electroosmotic flow is generated and controlled by electroosmotic flow pumps integrated on the substrate or positioned in relation thereto. Thereby, cells can be positioned in favorable measurement configuration at a plurality of sites for performing testing and measurements. Also, the invention relates to a main electric circuit for performing testing and measurements on a plurality of cells in parallel.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: August 23, 2005
    Assignee: Sophion Bioscience A/S
    Inventors: Morten Bech, Jørgen Due, Lars Thomsen, Jonatan Kutchinsky, Rafael Taboryski, Bent Erling Nielsen, John Shaw, John Dodgson
  • Publication number: 20020063067
    Abstract: The present invention relates to a high through-put system for determining and/or monitoring electrophysiological properties of ion channels of ion channel-containing membranes, typically lipid membrane-containing structures such as cells. In particular, the invention provides a substrate which provides means for automatically positioning cells at measuring sites using electroosmotic flow in canals formed on or in the substrate. The electroosmotic flow is generated and controlled by electroosmotic flow pumps integrated on the substrate or positioned in relation thereto. Thereby, cells can be positioned in favorable measurement configuration at a plurality of sites for performing testing and measurements. Also, the invention relates to a main electric circuit for performing testing and measurements on a plurality of cells in parallel.
    Type: Application
    Filed: October 2, 2001
    Publication date: May 30, 2002
    Inventors: Morten Bech, Jorgen Due, Lars Thomsen, Jonatan Kutchinsky, Rafael Taboryski, Bent Erling Nielsen, John Shaw, John Dodgson