Patents by Inventor Benwen CAO

Benwen CAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Deuterated diaminopyrimidine compounds and pharmaceutical compositions comprising such compounds
    Patent number: 10618884
    Abstract: Deuterated diaminopyrimidine compounds, and intermediates thereof are described. In particular, disclosed are deuterated diaminopyrimidine compounds of formula (I), and pharmaceutical compositions containing such compounds or crystal forms, pharmaceutically acceptable salt, hydrates or solvates thereof. The disclosed deuterated diaminopyrimidine compounds can be used for treating and/or preventing protein kinase-associated diseases, such as cell proliferative disease, cancer, immune disease and the like.
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: April 14, 2020
    Assignee: Suzhou Zelgen Biopharmaceuticals Co., Ltd.
    Inventors: Binhua Lv, Chengwei Li, Benwen Cao, Xudong Pang
  • DEUTERATED DIAMINOPYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS
    Publication number: 20180044323
    Abstract: Deuterated diaminopyrimidine compounds, and intermediates thereof are described. In particular, disclosed are deuterated diaminopyrimidine compounds of formula (I), and pharmaceutical compositions containing such compounds or crystal forms, pharmaceutically acceptable salt, hydrates or solvates thereof. The disclosed deuterated diaminopyrimidine compounds can be used for treating and/or preventing protein kinase-associated diseases, such as cell proliferative disease, cancer, immune disease and the like.
    Type: Application
    Filed: October 23, 2017
    Publication date: February 15, 2018
    Inventors: Binhua LV, Chengwei LI, Benwen CAO, Xudong PANG
  • Deuterated diaminopyrimidine compounds and pharmaceutical compositions comprising such compounds
    Patent number: 9809572
    Abstract: Deuterated diaminopyrimidine compounds and pharmaceutical compositions containing such compounds are described. In particular, disclosed are deuterated diaminopyrimidine compounds of formula (I), and pharmaceutical compositions containing such compounds or crystal forms, pharmaceutically acceptable salt, hydrates or solvates thereof. The disclosed deuterated diaminopyrimidine compounds can be used for treating and/or preventing protein kinase-associated diseases, such as cell proliferative disease, cancer, immune disease and the like.
    Type: Grant
    Filed: April 22, 2014
    Date of Patent: November 7, 2017
    Assignee: Suzhou Zelgen Biopharmaceuticals Co., Ltd.
    Inventors: Binhua Lv, Chengwei Li, Benwen Cao, Xudong Pang
  • Deuterated phenyl amino pyrimidine compound and pharmaceutical composition containing the same
    Patent number: 9604935
    Abstract: The present invention relates to a deuterated phenyl amino pyrimidine compound and pharmaceutical composition containing the same. Specifically provided are a deuterated phenyl amino pyrimidine compound as represented by formula (I), and pharmaceutical composition containing the compound, or polymorph, pharmaceutically acceptable salt, hydrate or solvate thereof. The compound of the present invention can treat and/or prevent JAK kinase-related diseases, such as bone marrow proliferative disease, cancer, immunologic diseases and the like.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: March 28, 2017
    Assignee: Suzhou Zelgen Biopharmaceuticals Co., Ltd.
    Inventors: Binhua LV, Zelin Sheng, Benwen Cao
  • DEUTERATED DIAMINOPYRIMIDINE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS
    Publication number: 20160185753
    Abstract: Deuterated diaminopyrimidine compounds and pharmaceutical compositions containing such compounds are described. In particular, disclosed are deuterated diaminopyrimidine compounds of formula (I), and pharmaceutical compositions containing such compounds or crystal forms, pharmaceutically acceptable salt, hydrates or solvates thereof. The disclosed deuterated diaminopyrimidine compounds can be used for treating and/or preventing protein kinase-associated diseases, such as cell proliferative disease, cancer, immune disease and the like.
    Type: Application
    Filed: April 22, 2014
    Publication date: June 30, 2016
    Applicant: SUZHOU ZELGEN BIOPHARMACEUTICALS CO., LTD.
    Inventors: Binhua LV, Chengwei LI, Benwen CAO, Xudonf PANG
  • DEUTERATED PHENYL AMINO PYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
    Publication number: 20160060227
    Abstract: The present invention relates to a deuterated phenyl amino pyrimidine compound and pharmaceutical composition containing the same. Specifically provided are a deuterated phenyl amino pyrimidine compound as represented by formula (I), and pharmaceutical composition containing the compound, or polymorph, pharmaceutically acceptable salt, hydrate or solvate thereof. The compound of the present invention can treat and/or prevent JAK kinase-related diseases, such as bone marrow proliferative disease, cancer, immunologic diseases and the like.
    Type: Application
    Filed: January 28, 2014
    Publication date: March 3, 2016
    Inventors: Binhua LV, Zelin SHENG, Benwen CAO