Abstract: Disclosed are a fibroin with increased molecular weight and improved antioxidant activity, tyrosinase inhibitory ability and cytotoxicity to cancer cells, which has a molecular structure modified by irradiation, a method for production thereof, use of the irradiated fibroin in various applications for enhancing antioxidant activity, tyrosinase inhibitory ability and/or cytotoxicity to cancer cells such as foods, cosmetics, medicines, etc.

Abstract: Disclosed are sericin having improved antioxidant and tyrosinase inhibitory abilities and increased molecular weight by irradiation, which causes a modification of a sericin molecular structure, a preparation method thereof and use of the irradiated sericin in various applications including food products, cosmetics and/or pharmaceutical products and medicines to improve antioxidant ability and/or tyrosinase inhibitory functions.

Abstract: Disclosed is an irradiation method which includes addition of vitamin C during sterilization of bone restorative demineralized bone matrix (DBM) with irradiation, so as to inhibit reduction of physical properties of a carrier containing DBM caused by irradiation and protect DBM formable bone morphogenetic protein (BMP) from irradiation. The method according to the present invention can provide bone restorative materials with more excellent stability and effectively controlled modification of physical properties by employing a sterilization process accompanied with addition of vitamin C during irradiation.

Abstract: Disclosed is a method for producing demineralized bone matrix with improvement of releasing bone morphogenetic protein by irradiating the demineralized bone matrix, the demineralized bone matrix produced by the producing method, a method for extracting bone morphogenetic protein using the demineralized bone matrix, and the bone morphogenetic protein extracted by the extracting method. The demineralized bone matrix produced according to the present invention and the bone morphogenetic protein extracted by using the demineralized bone matrix can be advantageously used in manufacturing bone restorative implants, bone growth accelerating compositions, and/or health aids or supplementary food products.